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Disease Models, Animal
Chronic acid water feeding protects mice against lethal gut-derived sepsis due to Pseudomonas aeruginosa.
Pseudomonas aeruginosa expresses a lethal virulence determinant, the PA-I lectin/adhesin, in the intestinal tract of a stressed host: the role of epithelia cell contact and molecules of the Quorum Sensing Signaling System.
Structure-function aspects of PstS in multi-drug-resistant Pseudomonas aeruginosa.
Surgical injury and metabolic stress enhance the virulence of the human opportunistic pathogen Pseudomonas aeruginosa.
Novel model to study combined effects of microorganisms and oxidants on development of intestinal necrosis.
Pseudomonas aeruginosa potentiates the lethal effect of intestinal ischemia-reperfusion injury: the role of in vivo virulence activation.
High-molecular-weight polyethylene glycol protects cardiac myocytes from hypoxia- and reoxygenation-induced cell death and preserves ventricular function.
Host stress and virulence expression in intestinal pathogens: development of therapeutic strategies using mice and C. elegans.
High molecular weight polyethylene glycol (PEG 15-20) maintains mucosal microbial barrier function during intestinal graft preservation.
Pseudomonas aeruginosa wound infection involves activation of its iron acquisition system in response to fascial contact.
Agent-based model of epithelial host-pathogen interactions in anastomotic leak.
Modeling Acinetobacter baumannii wound infections: The critical role of iron.
Collapse of the Microbiome, Emergence of the Pathobiome, and the Immunopathology of Sepsis.
Oral Polyphosphate Suppresses Bacterial Collagenase Production and Prevents Anastomotic Leak Due to Serratia marcescens and Pseudomonas aeruginosa.
Can Methicillin-resistant Staphylococcus aureus Silently Travel From the Gut to the Wound and Cause Postoperative Infection? Modeling the "Trojan Horse Hypothesis".
Enterococcus faecalis exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets.
Prevention of Anastomotic Leak Via Local Application of Tranexamic Acid to Target Bacterial-mediated Plasminogen Activation: A Practical Solution to a Complex Problem.
Low-fat/high-fibre diet prehabilitation improves anastomotic healing via the microbiome: an experimental model.
Can the Cecal Ligation and Puncture Model Be Repurposed To Better Inform Therapy in Human Sepsis?
Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate.