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One or more keywords matched the following items that are connected to Gajewski, Thomas F.
Item TypeName
Concept Melanoma, Experimental
Concept Melanoma
Concept gp100 Melanoma Antigen
Academic Article Rational development of tumour antigen-specific immunization in melanoma.
Academic Article Monitoring specific T-cell responses to melanoma vaccines: ELISPOT, tetramers, and beyond.
Academic Article Immunization of HLA-A2+ melanoma patients with MAGE-3 or MelanA peptide-pulsed autologous peripheral blood mononuclear cells plus recombinant human interleukin 12.
Academic Article Immunization with Melan-A peptide-pulsed peripheral blood mononuclear cells plus recombinant human interleukin-12 induces clinical activity and T-cell responses in advanced melanoma.
Academic Article Temozolomide for melanoma: new toxicities and new opportunities.
Academic Article Semiquantitative analysis of dynamic contrast enhanced MRI in cancer patients: Variability and changes in tumor tissue over time.
Academic Article Depletion of normal B cells with rituximab as an adjunct to IL-2 therapy for renal cell carcinoma and melanoma.
Academic Article Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro.
Academic Article Innovations and challenges in melanoma: summary statement from the first Cambridge conference.
Academic Article Phase 2 study of the g209-2M melanoma peptide vaccine and low-dose interleukin-2 in advanced melanoma: Cancer and Leukemia Group B 509901.
Academic Article Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.
Academic Article Tumor progression despite massive influx of activated CD8(+) T cells in a patient with malignant melanoma ascites.
Academic Article Phase II study of the Flk-1 tyrosine kinase inhibitor SU5416 in advanced melanoma.
Academic Article Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma.
Academic Article Phase I/II trial of tremelimumab in patients with metastatic melanoma.
Academic Article Melanoma presenting as circulating tumor cells associated with failed angiogenesis.
Academic Article Failure at the effector phase: immune barriers at the level of the melanoma tumor microenvironment.
Academic Article Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment.
Academic Article Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment.
Academic Article A phase II study of oxaliplatin, docetaxel, and GM-CSF in patients with previously treated advanced melanoma.
Academic Article Cross-priming of T cells to intracranial tumor antigens elicits an immune response that fails in the effector phase but can be augmented with local immunotherapy.
Academic Article Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study.
Academic Article Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy.
Academic Article Improved melanoma survival at last! Ipilimumab and a paradigm shift for immunotherapy.
Academic Article Molecular profiling of melanoma and the evolution of patient-specific therapy.
Academic Article Future perspectives in melanoma research. Meeting report from the "Melanoma research: a bridge from Naples to the World. Napoli, December 5th-6th 2011".
Academic Article Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells.
Academic Article Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases.
Academic Article Cellular and molecular requirements for rejection of B16 melanoma in the setting of regulatory T cell depletion and homeostatic proliferation.
Academic Article A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3.
Academic Article CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
Academic Article Immune-mediated red cell aplasia after anti-CTLA-4 immunotherapy for metastatic melanoma.
Academic Article Ocular melanoma metastasis to the cervical spine.
Academic Article Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".
Academic Article Phase II study of the Src kinase inhibitor saracatinib (AZD0530) in metastatic melanoma.
Academic Article Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).
Academic Article Imatinib for melanomas harboring mutationally activated or amplified KIT arising on mucosal, acral, and chronically sun-damaged skin.
Academic Article Phase 2 study of RO4929097, a gamma-secretase inhibitor, in metastatic melanoma: SWOG 0933.
Academic Article Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b study.
Academic Article Future perspectives in melanoma research: meeting report from the "Melanoma Bridge", Napoli, December 5th-8th 2013.
Academic Article Therapeutic activity of high-dose intratumoral IFN-ß requires direct effect on the tumor vasculature.
Academic Article Metabolic response by FDG-PET to imatinib correlates with exon 11 KIT mutation and predicts outcome in patients with mucosal melanoma.
Academic Article The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma.
Academic Article STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Academic Article Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells.
Academic Article Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial.
Academic Article Phase II Study of Nilotinib in Melanoma Harboring KIT Alterations Following Progression to Prior KIT Inhibition.
Academic Article Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints.
Academic Article Melanoma-intrinsic ß-catenin signalling prevents anti-tumour immunity.
Academic Article Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy.
Academic Article Future perspectives in melanoma research: meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014.
Academic Article Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
Academic Article A phase II study of cediranib, an oral VEGF inhibitor, in previously untreated patients with metastatic or recurrent malignant melanoma.
Academic Article Single dose denileukin diftitox does not enhance vaccine-induced T cell responses or effectively deplete Tregs in advanced melanoma: immune monitoring and clinical results of a randomized phase II trial.
Academic Article Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
Academic Article Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.
Academic Article Density of immunogenic antigens does not explain the presence or absence of the T-cell-inflamed tumor microenvironment in melanoma.
Academic Article Relationship between physician-adjudicated adverse events and patient-reported health-related quality of life in a phase II clinical trial (NCT01143402) of patients with metastatic uveal melanoma.
Academic Article Human melanomas and ovarian cancers overexpressing mechanical barrier molecule genes lack immune signatures and have increased patient mortality risk.
Academic Article Phase 2 trial of talabostat in stage IV melanoma.
Academic Article Reciprocal expression of indoleamine-2,3-dioxygenase (IDO) and arginase-I in metastatic melanoma tumors.
Academic Article Efficacy and safety of ipilimumab induction and maintenance dosing in patients with advanced melanoma who progressed on one or more prior therapies.
Academic Article Safety and efficacy of the antiganglioside GD3 antibody ecromeximab (KW2871) combined with high-dose interferon-a2b in patients with metastatic melanoma.
Academic Article Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy.
Academic Article Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy).
Academic Article The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients.
Academic Article Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.
Academic Article Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity.
Academic Article Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy.
Academic Article An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0.
Academic Article Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity.
Academic Article Severe hemophagocytic lymphohistiocytosis in a melanoma patient treated with ipilimumab + nivolumab.
Academic Article WNT/ß-catenin Pathway Activation Correlates with Immune Exclusion across Human Cancers.
Academic Article Major pathologic response on biopsy (MPRbx) in patients with advanced melanoma treated with anti-PD-1: evidence for an early, on-therapy biomarker of response.
Academic Article Phase 1/2 study of epacadostat in combination with ipilimumab in patients with unresectable or metastatic melanoma.
Academic Article Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study.
Academic Article Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th-1 December 1st, 2018, Naples, Italy).
Academic Article Secondary resistance to immunotherapy associated with ß-catenin pathway activation or PTEN loss in metastatic melanoma.
Academic Article Extended 5-Year Follow-up Results of a Phase Ib Study (BRIM7) of Vemurafenib and Cobimetinib in BRAF-Mutant Melanoma.
Academic Article Major pathologic response on biopsy (MPRbx) in patients with advanced melanoma treated with anti-PD-1: evidence for an early, on-therapy biomarker of response.
Academic Article A case of dual-mechanism immune-related anaemia in a patient with metastatic melanoma treated with nivolumab and ipilimumab.
Academic Article Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy).
Academic Article Novel response to neoadjuvant anti-PD1 therapy for a patient with retrocaval melanotic schwannoma.
Academic Article Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma.
Academic Article Cost-Effectiveness Analysis of Adjuvant Therapy for BRAF-Mutant Resected Stage III Melanoma in Medicare Patients.
Academic Article Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd-5th, 2020, Italy).
Academic Article ASO Visual Abstract: Cost-Effectiveness Analysis of Adjuvant Therapy for BRAF-Mutant Resected Stage 3 Melanoma in Medicare Patients.
Academic Article Immune cell and tumor cell-derived CXCL10 is indicative of immunotherapy response in metastatic melanoma.
Academic Article Wilms tumor reveals DNA repair gene hyperexpression is linked to lack of tumor immune infiltration.
Academic Article Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma.
Academic Article Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd - 4th, 2021, Italy).
Academic Article Germline immunomodulatory expression quantitative trait loci (ieQTLs) associated with immune-related toxicity from checkpoint inhibition.
Academic Article Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy).
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  • Melanoma