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Gajewski, Thomas F.
One or more keywords matched the following items that are connected to Gajewski, Thomas F.
Item TypeName
Concept Mice, Knockout
Academic Article Antigen recognition and allogeneic tumor rejection in CD8+ TCR transgenic/RAG(-/-) mice.
Academic Article The immune system as anti-tumor sentinel: molecular requirements for an anti-tumor immune response.
Academic Article Cutting edge: differentiation of antitumor CTL in vivo requires host expression of Stat1.
Academic Article Antigen-specific blockade of T cells in vivo using dimeric MHC peptide.
Academic Article CD28 is not required for c-Jun N-terminal kinase activation in T cells.
Academic Article Cutting edge: spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice.
Academic Article Absence of CTLA-4 lowers the activation threshold of primed CD8+ TCR-transgenic T cells: lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase.
Academic Article Cutting edge: targeted ligation of CTLA-4 in vivo by membrane-bound anti-CTLA-4 antibody prevents rejection of allogeneic cells.
Academic Article Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells.
Academic Article Protein kinase Ctheta focusing at the cSMAC is a consequence rather than cause of TCR signaling and is dependent on the MEK/ERK pathway.
Academic Article ICAM-1 contributes to but is not essential for tumor antigen cross-priming and CD8+ T cell-mediated tumor rejection in vivo.
Academic Article Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells.
Academic Article Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells.
Academic Article Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases.
Academic Article CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells.
Academic Article Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-?1 phosphorylation.
Academic Article Cellular and molecular requirements for rejection of B16 melanoma in the setting of regulatory T cell depletion and homeostatic proliferation.
Academic Article Expression and function of CTLA-4 in Th1 and Th2 cells.
Academic Article PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model.
Academic Article Beta-catenin does not regulate memory T cell phenotype.
Academic Article Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy.
Academic Article Therapeutic activity of high-dose intratumoral IFN-ß requires direct effect on the tumor vasculature.
Academic Article STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
Academic Article STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Academic Article Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints.
Academic Article Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA.
Academic Article Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy.
Academic Article Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity.
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  • Mice Knockout