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One or more keywords matched the following properties of Chmura, Steven
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keywords oligometastases, immunotherapy, radioimmunotherapy,Breast Cancer, @docace911, SBRT, XBOX
overview Dr. Steven J. Chmura is an Associate Professor in the Department of Radiation and Cellular Oncology and Director of Clinical and Translational Research at The University of Chicago. Steven J. Chmura MD, PhD is the director of Clinical and Translational Research for Radiation Oncology at the University of Chicago for over a decade. He has been actively involved in both the clinical implementation of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) and related translational and clinical research, as well as the integration of SRS and SBRT into other systemic therapies. His clinical interests include breast cancer, limited metastatic disease, immunotherapy, and technologic improvements in the delivery of radiotherapy. Dr. Chmura is a leader in the NCI cooperative groups. His work has led to the first international oligmetastatic trials through NRG Oncology examining the safety of treating lung and breast cancer patients as a Phase II/III trial examining potential improvements to progression-free survival and overall survival. Dr. Chmura's work in radio-immunology has also translated into multiple investigator-sponsored trials along with the now accruing NCI-sponsored (A091605) trial randomizing the role of SBRT combined with pembrolizumab in advanced Merkel cell carcinoma; such integration of ablative radiotherapy and immunotherapy along with advancing the search for biomarkers is currently Dr. Chmura's focus.
One or more keywords matched the following items that are connected to Chmura, Steven
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Concept Immunotherapy
Academic Article Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell-mediated killing.
Academic Article Rescue of Immunotherapy-Refractory Metastatic Merkel Cell Carcinoma With Conventionally Fractionated Radiotherapy and Concurrent Pembrolizumab.
Academic Article Integration of radiotherapy and immunotherapy for treatment of oligometastases.
Academic Article Tumor-reprogrammed resident T cells resist radiation to control tumors.
Academic Article The role of immunotherapy in combination with oligometastasis-directed therapy: a narrative review.
Academic Article Radiation treatment planning study to investigate feasibility of delivering Immunotherapy in Combination with Ablative Radiosurgery to Ultra-High DoSes (ICARUS).
Academic Article Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.
Academic Article CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer.
Academic Article Prospective Evaluation of Stereotactic Body Radiotherapy and Immunotherapy for Mediastinal and Hilar Lymph Node Metastases.
Academic Article Stereotactic Body Radiation Therapy and Immunotherapy in Abdominal and Pelvic Lymph Node Metastases.
Academic Article Evaluation of Initial Metastatic Tumor Location and Radiation Response to Determine Outcomes in Patients Who Received Combination Stereotactic Body Radiotherapy and Immunotherapy for NSCLC.
Academic Article Predictors of Pneumonitis in Combined Thoracic Stereotactic Body Radiation Therapy and Immunotherapy.
Academic Article Radiation dose, schedule, and novel systemic targets for radio-immunotherapy combinations.
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  • Immunotherapy