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One or more keywords matched the following properties of He, Yu-Ying
keywords Skin Cancer
overview Our research addresses the fundamental questions: how normal cells respond to environmental carcinogens and evolve into cancerous cells. In particular, our group focuses on the role of epitranscriptomics, epigenetics, and autophagy in regulating genomic integrity and cellular homeostasis and to investigate their impact on cancer development and therapeutic resistance, with an emphasis on skin cancer including squamous cancer and melanoma. Our long-term goal is to identify previously unrecognized, therapeutically accessible molecular regulatory networks that predict susceptibility to skin cancer, and improve our ability to prevent and treat these cancers.
One or more keywords matched the following items that are connected to He, Yu-Ying
Item TypeName
Concept Skin Neoplasms
Academic Article Immunosuppressive cyclosporin A activates AKT in keratinocytes through PTEN suppression: implications in skin carcinogenesis.
Academic Article PTEN positively regulates UVB-induced DNA damage repair.
Academic Article UVA induces lesions resembling seborrheic keratoses in mice with keratinocyte-specific PTEN downregulation.
Academic Article Deregulation of XPC and CypA by cyclosporin A: an immunosuppression-independent mechanism of skin carcinogenesis.
Academic Article Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C.
Academic Article PTEN: new insights into its regulation and function in skin cancer.
Academic Article Autophagy controls p38 activation to promote cell survival under genotoxic stress.
Academic Article Suppression of PTEN transcription by UVA.
Academic Article C/EBPa expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPa confers susceptibility to UVB-induced skin squamous cell carcinomas.
Academic Article Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin.
Academic Article Recent advances in the prevention and treatment of skin cancer using photodynamic therapy.
Academic Article SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer.
Academic Article Autophagy positively regulates DNA damage recognition by nucleotide excision repair.
Academic Article Ultraviolet radiation-induced non-melanoma skin cancer: Regulation of DNA damage repair and inflammation.
Academic Article Molecular regulation of UV-induced DNA repair.
Academic Article Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells.
Academic Article Autophagy in UV Damage Response.
Academic Article Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation.
Academic Article Mechanisms and prevention of UV-induced melanoma.
Academic Article The Autophagy Receptor Adaptor p62 is Up-regulated by UVA Radiation in Melanocytes and in Melanoma Cells.
Academic Article Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer.
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  • Skin Neoplasms