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The University of Chicago

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Sisodia, Sangram

One or more keywords matched the following items that are connected to Sisodia, Sangram

Item Type	Name
Concept	Hydrolysis
Academic Article	Endoproteolytic processing and stabilization of wild-type and mutant presenilin.
Academic Article	Proteolytic processing of familial British dementia-associated BRI variants: evidence for enhanced intracellular accumulation of amyloidogenic peptides.
Academic Article	Familial Alzheimer disease-linked presenilin 1 variants enhance production of both Abeta 1-40 and Abeta 1-42 peptides that are only partially sensitive to a potent aspartyl protease transition state inhibitor of "gamma-secretase".
Academic Article	A sequence within the first transmembrane domain of PEN-2 is critical for PEN-2-mediated endoproteolysis of presenilin 1.
Academic Article	Evidence that the "NF" motif in transmembrane domain 4 of presenilin 1 is critical for binding with PEN-2.
Academic Article	Metabolism of the "Swedish" amyloid precursor protein variant in Madin-Darby canine kidney cells.
Academic Article	The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage.

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Hydrolysis