| Item Type | Name |
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Concept
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Complement System Proteins
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Concept
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Complement Pathway, Classical
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Concept
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Complement C9
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Concept
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Complement C3b
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Concept
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Complement Inactivator Proteins
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Concept
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Complement Activation
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Concept
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Complement C3
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Concept
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Complement C4
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Concept
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Complement C5
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Concept
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Complement Factor B
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Concept
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Receptors, Complement
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Concept
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Complement C5a
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Concept
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Complement Membrane Attack Complex
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Concept
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Complement C3d
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Concept
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Complement Factor H
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Concept
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Complement C5b
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Concept
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Complement Inactivating Agents
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Concept
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Receptors, Complement 3d
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Concept
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Complement C3a
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Concept
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Receptors, Complement 3b
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Concept
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Complement Pathway, Alternative
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Academic Article
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Characterization of C3-binding proteins on mouse neutrophils and platelets.
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Academic Article
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Inhibition of complement regulation is key to the pathogenesis of active Heymann nephritis.
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Academic Article
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Immune complex glomerulonephritis in C4- and C3-deficient mice.
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Academic Article
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Production of the rat complement regulator, Crry, as an active soluble protein in Pichia pastoris.
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Academic Article
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Production and functional analysis of rat CD59 and chimeric CD59-Crry as active soluble proteins in Pichia pastoris.
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Academic Article
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Characterization of C3 receptors on cultured rat glomerular endothelial cells.
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Academic Article
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Renal, central nervous system and pancreatic overexpression of recombinant soluble Crry in transgenic mice. A novel means of protection from complement-mediated injury.
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Academic Article
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Expression of a soluble complement inhibitor protects transgenic mice from antibody-induced acute renal failure.
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Academic Article
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Complement is activated in kidney by endotoxin but does not cause the ensuing acute renal failure.
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Academic Article
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A protein with characteristics of factor H is present on rodent platelets and functions as the immune adherence receptor.
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Academic Article
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Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury.
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Academic Article
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Glomerular complement regulation is overwhelmed in passive Heymann nephritis.
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Academic Article
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A complement-dependent model of thrombotic thrombocytopenic purpura induced by antibodies reactive with endothelial cells.
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Academic Article
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Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.
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Academic Article
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Use of complement inhibitors in tissue injury.
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Academic Article
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The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.
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Academic Article
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Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytes.
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Academic Article
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Excessive matrix accumulation in the kidneys of MRL/lpr lupus mice is dependent on complement activation.
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Academic Article
|
Rat glomerular epithelial cells produce and bear factor H on their surface that is up-regulated under complement attack.
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Academic Article
|
Complement and autoimmune glomerular diseases.
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Academic Article
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Administration of the soluble complement inhibitor, Crry-Ig, reduces inflammation and aquaporin 4 expression in lupus cerebritis.
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Academic Article
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Isolation and characterization of a novel rat factor H-related protein that is up-regulated in glomeruli under complement attack.
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Academic Article
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Complement and the kidney.
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Academic Article
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Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes.
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Academic Article
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Overexpression of complement inhibitor Crry does not prevent cryoglobulin-associated membranoproliferative glomerulonephritis.
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Academic Article
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Role of complement and complement regulatory proteins in glomerulonephritis.
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Academic Article
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Contrasting roles of complement activation and its regulation in membranous nephropathy.
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Academic Article
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Treatment of glomerulonephritis: will we ever have options other than steroids and cytotoxics?
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Academic Article
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Administration of a soluble recombinant complement C3 inhibitor protects against renal disease in MRL/lpr mice.
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Academic Article
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C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist.
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Academic Article
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Mouse podocyte complement factor H: the functional analog to human complement receptor 1.
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Academic Article
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Complement-dependent apoptosis and inflammatory gene changes in murine lupus cerebritis.
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Academic Article
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Distinct and separable roles of the complement system in factor H-deficient bone marrow chimeric mice with immune complex disease.
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Academic Article
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CR1/CR2 deficiency alters IgG3 autoantibody production and IgA glomerular deposition in the MRL/lpr model of SLE.
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Academic Article
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Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure.
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Academic Article
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The role of the complement cascade in endotoxin-induced septic encephalopathy.
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Academic Article
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Absence of functional alternative complement pathway alleviates lupus cerebritis.
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Academic Article
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The many effects of complement C3- and C5-binding proteins in renal injury.
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Academic Article
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Complement inhibitors targeted to the proximal tubule prevent injury in experimental nephrotic syndrome and demonstrate a key role for C5b-9.
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Academic Article
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Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritis.
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Academic Article
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The simple design of complement factor H: Looks can be deceiving.
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Academic Article
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Inhibition of C5a receptor alleviates experimental CNS lupus.
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Academic Article
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C5a alters blood-brain barrier integrity in experimental lupus.
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Academic Article
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Decay-accelerating factor but not CD59 limits experimental immune-complex glomerulonephritis.
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Academic Article
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Complement in lupus nephritis: the good, the bad, and the unknown.
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Academic Article
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New approaches to the treatment of dense deposit disease.
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Academic Article
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Distinct roles for C3a and C5a in complement-induced tubulointerstitial injury.
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Academic Article
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C5a/CD88 signaling alters blood-brain barrier integrity in lupus through nuclear factor-?B.
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Academic Article
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Experimental membranous nephropathy redux.
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Academic Article
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Pathogenic natural antibodies recognizing annexin IV are required to develop intestinal ischemia-reperfusion injury.
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Academic Article
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Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.
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Academic Article
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C3aR inhibition reduces neurodegeneration in experimental lupus.
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Academic Article
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Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes.
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Academic Article
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Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis.
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Academic Article
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The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H-deficient mice.
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Academic Article
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Characterization of rat complement receptors and regulatory proteins. CR2 and Crry are conserved, and the C3b receptor of neutrophils and platelets is distinct from CR1.
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Academic Article
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Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells.
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Academic Article
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Molecular characterization of rat Crry: widespread distribution of two alternative forms of Crry mRNA.
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Academic Article
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Crry and CD59 regulate complement in rat glomerular epithelial cells and are inhibited by the nephritogenic antibody of passive Heymann nephritis.
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Academic Article
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Alteration in kidney glucose and amino acids are implicated in renal pathology in MRL/lpr mice.
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Academic Article
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Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor.
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Academic Article
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Inhibiting the complement system does not reduce injury in renal ischemia reperfusion.
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Academic Article
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Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice.
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Academic Article
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Complement factor h limits immune complex deposition and prevents inflammation and scarring in glomeruli of mice with chronic serum sickness.
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Academic Article
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C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
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Academic Article
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Complement factor H deficiency accelerates development of lupus nephritis.
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Academic Article
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Curcumin alleviates immune-complex-mediated glomerulonephritis in factor-H-deficient mice.
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Academic Article
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CD11b is protective in complement-mediated immune complex glomerulonephritis.
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Academic Article
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Transcriptional profiling reveals that C5a alters microRNA in brain endothelial cells.
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Academic Article
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C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus.
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Academic Article
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Abrogation of immune complex glomerulonephritis by native carboxypeptidase and pharmacological antagonism of the C5a receptor.
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Academic Article
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Complement in Lupus Nephritis: New Perspectives.
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Academic Article
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Complement regulation in renal disease models.
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Academic Article
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Complement activation in the tubulointerstitium: AKI, CKD, and in between.
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Academic Article
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Immunomodulatory Role of Complement Proteins in the Neuropathology Associated with Opiate Abuse and HIV-1 Co-Morbidity.
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Academic Article
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C5a induces caspase-dependent apoptosis in brain vascular endothelial cells in experimental lupus.
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Academic Article
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Muscle, myeloid cells, and complement: a complex interaction.
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Academic Article
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Taming hemodialysis-induced inflammation: Are complement C3 inhibitors a viable option?
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Academic Article
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Absence of complement factor H alters bone architecture and dynamics.
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Academic Article
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Absence of complement factor H reduces physical performance in C57BL6 mice.
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Academic Article
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Local complement factor H protects kidney endothelial cell structure and function.
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Academic Article
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Improving Clinical Trials for Anticomplement Therapies in Complement-Mediated Glomerulopathies: Report of a Scientific Workshop Sponsored by the National Kidney Foundation.
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Academic Article
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Macrophage Depletion Reduces Disease Pathology in Factor H-Dependent Immune Complex-Mediated Glomerulonephritis.
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Grant
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Targeting complement inhibitors to the human proximal tubule
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Grant
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COMPLEMENT ACTIVATION OF THE GLOMERULER EPITHELIAL CELL
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Grant
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Nephrology Research Training Grant
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Grant
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Role of the Complement System in Renal Disease
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Grant
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Pathogenic role of the complement system in murine lupus
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Grant
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Role of the complement system in renal disease
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Academic Article
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Complement: Functions, location and implications.
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