| Item Type | Name |
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Concept
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Mice, Inbred C3H
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Concept
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Mice, Inbred Strains
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Concept
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Mice, Transgenic
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Nude
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Concept
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Mice, Inbred NZB
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Concept
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Mice, Knockout
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Concept
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Mice, Inbred MRL lpr
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Concept
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Mice
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Concept
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Mice, Mutant Strains
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Concept
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Mice, SCID
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Concept
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Mice, Inbred NOD
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Academic Article
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Characterization of C3-binding proteins on mouse neutrophils and platelets.
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Academic Article
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Immune complex glomerulonephritis in C4- and C3-deficient mice.
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Academic Article
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Characterization of C3 receptors on cultured rat glomerular endothelial cells.
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Academic Article
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Renal, central nervous system and pancreatic overexpression of recombinant soluble Crry in transgenic mice. A novel means of protection from complement-mediated injury.
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Academic Article
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Expression of a soluble complement inhibitor protects transgenic mice from antibody-induced acute renal failure.
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Academic Article
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Complement is activated in kidney by endotoxin but does not cause the ensuing acute renal failure.
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Academic Article
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A protein with characteristics of factor H is present on rodent platelets and functions as the immune adherence receptor.
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Academic Article
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Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury.
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Academic Article
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A complement-dependent model of thrombotic thrombocytopenic purpura induced by antibodies reactive with endothelial cells.
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Academic Article
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Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.
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Academic Article
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The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.
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Academic Article
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Excessive matrix accumulation in the kidneys of MRL/lpr lupus mice is dependent on complement activation.
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Academic Article
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Administration of the soluble complement inhibitor, Crry-Ig, reduces inflammation and aquaporin 4 expression in lupus cerebritis.
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Academic Article
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Prominent renal expression of a murine leukemia retrovirus in experimental systemic lupus erythematosus.
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Academic Article
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Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes.
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Academic Article
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Role of Toll-like receptor 4 in endotoxin-induced acute renal failure.
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Academic Article
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Acute renal failure in endotoxemia is dependent on caspase activation.
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Academic Article
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Overexpression of complement inhibitor Crry does not prevent cryoglobulin-associated membranoproliferative glomerulonephritis.
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Academic Article
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Administration of a soluble recombinant complement C3 inhibitor protects against renal disease in MRL/lpr mice.
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Academic Article
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C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist.
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Academic Article
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Mouse podocyte complement factor H: the functional analog to human complement receptor 1.
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Academic Article
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Anti-diabetic effect of ginsenoside Re in ob/ob mice.
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Academic Article
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Complement-dependent apoptosis and inflammatory gene changes in murine lupus cerebritis.
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Academic Article
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Distinct and separable roles of the complement system in factor H-deficient bone marrow chimeric mice with immune complex disease.
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Academic Article
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CR1/CR2 deficiency alters IgG3 autoantibody production and IgA glomerular deposition in the MRL/lpr model of SLE.
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Academic Article
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Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure.
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Academic Article
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The role of the complement cascade in endotoxin-induced septic encephalopathy.
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Academic Article
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Absence of functional alternative complement pathway alleviates lupus cerebritis.
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Academic Article
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Negative regulation of CD40-mediated B cell responses by E3 ubiquitin ligase Casitas-B-lineage lymphoma protein-B.
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Academic Article
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Focal and segmental glomerulosclerosis induced in mice lacking decay-accelerating factor in T cells.
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Academic Article
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Altered thymic selection by overexpressing cellular FLICE inhibitory protein in T cells causes lupus-like syndrome in a BALB/c but not C57BL/6 strain.
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Academic Article
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Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritis.
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Academic Article
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The simple design of complement factor H: Looks can be deceiving.
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Academic Article
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An integrated strategy for the optimization of microarray data interpretation.
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Academic Article
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Inhibition of C5a receptor alleviates experimental CNS lupus.
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Academic Article
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C5a alters blood-brain barrier integrity in experimental lupus.
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Academic Article
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Systemic lupus erythematosus and the brain: what mice are telling us.
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Academic Article
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Decay-accelerating factor but not CD59 limits experimental immune-complex glomerulonephritis.
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Academic Article
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Distinct roles for C3a and C5a in complement-induced tubulointerstitial injury.
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Academic Article
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Renoprotective role of the vitamin D receptor in diabetic nephropathy.
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Academic Article
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Inhibition of NF-kappaB-dependent Bcl-xL expression by clusterin promotes albumin-induced tubular cell apoptosis.
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Academic Article
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C5a/CD88 signaling alters blood-brain barrier integrity in lupus through nuclear factor-?B.
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Academic Article
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Chronic kidney disease induced in mice by reversible unilateral ureteral obstruction is dependent on genetic background.
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Academic Article
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Pathogenic natural antibodies recognizing annexin IV are required to develop intestinal ischemia-reperfusion injury.
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Academic Article
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Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.
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Academic Article
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C3aR inhibition reduces neurodegeneration in experimental lupus.
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Academic Article
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Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes.
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Academic Article
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Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis.
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Academic Article
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The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H-deficient mice.
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Academic Article
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Characterization of rat complement receptors and regulatory proteins. CR2 and Crry are conserved, and the C3b receptor of neutrophils and platelets is distinct from CR1.
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Academic Article
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TNF is a key mediator of septic encephalopathy acting through its receptor, TNF receptor-1.
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Academic Article
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Alteration in kidney glucose and amino acids are implicated in renal pathology in MRL/lpr mice.
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Academic Article
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miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130.
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Academic Article
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MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy.
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Academic Article
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Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor.
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Academic Article
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Inhibiting the complement system does not reduce injury in renal ischemia reperfusion.
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Academic Article
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Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney.
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Academic Article
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Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice.
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Academic Article
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Complement factor h limits immune complex deposition and prevents inflammation and scarring in glomeruli of mice with chronic serum sickness.
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Academic Article
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MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.
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Academic Article
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Altered vitamin D metabolism in type II diabetic mouse glomeruli may provide protection from diabetic nephropathy.
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Academic Article
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C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
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Academic Article
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Renal FcRn reclaims albumin but facilitates elimination of IgG.
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Academic Article
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Characterization of novel VEGF (vascular endothelial growth factor)-C splicing isoforms from mouse.
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Academic Article
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Complement factor H deficiency accelerates development of lupus nephritis.
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Academic Article
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Curcumin alleviates immune-complex-mediated glomerulonephritis in factor-H-deficient mice.
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Academic Article
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Contrasting effects of systemic monocyte/macrophage and CD4+ T cell depletion in a reversible ureteral obstruction mouse model of chronic kidney disease.
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Academic Article
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CD11b is protective in complement-mediated immune complex glomerulonephritis.
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Academic Article
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Transcriptional profiling reveals that C5a alters microRNA in brain endothelial cells.
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Academic Article
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Abrogation of immune complex glomerulonephritis by native carboxypeptidase and pharmacological antagonism of the C5a receptor.
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Academic Article
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Complement regulation in renal disease models.
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Academic Article
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Chronic kidney disease, uremic milieu, and its effects on gut bacterial microbiota dysbiosis.
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Academic Article
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C5a induces caspase-dependent apoptosis in brain vascular endothelial cells in experimental lupus.
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Academic Article
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DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN.
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Academic Article
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Loss of diacylglycerol kinase epsilon in mice causes endothelial distress and impairs glomerular Cox-2 and PGE2 production.
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Academic Article
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Absence of complement factor H alters bone architecture and dynamics.
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Academic Article
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Curcumin aggravates CNS pathology in experimental systemic lupus erythematosus.
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Academic Article
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Absence of complement factor H reduces physical performance in C57BL6 mice.
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Academic Article
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Unconjugated p-cresol activates macrophage macropinocytosis leading to increased LDL uptake.
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Academic Article
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Local complement factor H protects kidney endothelial cell structure and function.
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Academic Article
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Macrophage Depletion Reduces Disease Pathology in Factor H-Dependent Immune Complex-Mediated Glomerulonephritis.
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Grant
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Massively Parallel Gene Expression Analysis
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Grant
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Nephrology Research Training Grant
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Grant
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Role of the Complement System in Renal Disease
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Grant
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Pathogenic role of the complement system in murine lupus
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Grant
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GENETIC AND PATHOLOGIC ALTERATIONS IN MURINE DIABETES
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