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One or more keywords matched the following properties of Rock, Ronald S.
overview Cells use an extensive toolkit of myosin motor proteins to traffic materials, anchor components, and control their shape. The focus of our group is to understand biological motion, specifically how motor proteins navigate the cytoskeleton and dynamically organize cells. We use a multifaceted approach, constructing advanced single-molecule fluorescence microscopes and optical tweezers to watch how myosins move in vitro and in whole cells. We also use structural biology tools to understand how myosin architecture and quaternary structure regulates motility.
One or more keywords matched the following items that are connected to Rock, Ronald S.
Item TypeName
Concept Myosin-Light-Chain Kinase
Concept Myosin Type II
Concept Myosin Subfragments
Concept Myosin Light Chains
Concept Nonmuscle Myosin Type IIB
Concept Myosin Heavy Chains
Concept Myosin Type V
Academic Article Myosin-V is a processive actin-based motor.
Academic Article Myosin-V stepping kinetics: a molecular model for processivity.
Academic Article In vitro assays of processive myosin motors.
Academic Article Myosin VI is a processive motor with a large step size.
Academic Article A crossbridge too far.
Academic Article A myosin motor that selects bundled actin for motility.
Academic Article The stepping pattern of myosin X is adapted for processive motility on bundled actin.
Academic Article Structured post-IQ domain governs selectivity of myosin X for fascin-actin bundles.
Academic Article Mechanosensing through cooperative interactions between myosin II and the actin crosslinker cortexillin I.
Academic Article A flexible domain is essential for the large step size and processivity of myosin VI.
Academic Article Unconventional myosin traffic in cells reveals a selective actin cytoskeleton.
Academic Article Molecular motors: a finicky myosin V chooses its own path.
Academic Article A myosin II mutation uncouples ATPase activity from motility and shortens step size.
Academic Article Unconventional processive mechanics of non-muscle myosin IIB.
Academic Article Myosin VI walks hand-over-hand along actin.
Academic Article Pharmacological activation of myosin II paralogs to correct cell mechanics defects.
Academic Article Actin age orchestrates myosin-5 and myosin-6 run lengths.
Academic Article Competition between Coiled-Coil Structures and the Impact on Myosin-10 Bundle Selection.
Academic Article Myosin light chain kinase steady-state kinetics: comparison of smooth muscle myosin II and nonmuscle myosin IIB as substrates.
Academic Article Investigations of human myosin VI targeting using optogenetically controlled cargo loading.
Academic Article Roux B, ed. Molecular Machines
Academic Article How Actin Tracks Affect Myosin Motors.
Academic Article Pushed to the edge: hundreds of Myosin 10s pack into filopodia and could cause traffic jams on actin.
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  • Nonmuscle Myosin Type IIB