Item Type | Name |
Concept
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Aged, 80 and over
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Concept
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Aged
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Concept
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Middle Aged
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Academic Article
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Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs.
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Academic Article
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Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.
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Academic Article
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Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.
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Academic Article
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Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
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Academic Article
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Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
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Academic Article
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Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
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Academic Article
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Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
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Academic Article
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Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
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Academic Article
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Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.
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Academic Article
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A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma.
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Academic Article
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Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
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Academic Article
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Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
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Academic Article
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Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.
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Academic Article
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Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
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Academic Article
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Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
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Academic Article
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The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
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Academic Article
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HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis.
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Academic Article
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Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
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Academic Article
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Phase I clinical trial using peptide vaccine for human vascular endothelial growth factor receptor 2 in combination with gemcitabine for patients with advanced pancreatic cancer.
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Academic Article
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Successful outcomes using combination therapy of interleukin-2 and interferon-alpha for renal cell carcinoma patients with lung metastasis.
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Academic Article
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Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
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Academic Article
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Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.
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Academic Article
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Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
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Academic Article
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A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
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Academic Article
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Impact of LIMK1, MMP2 and TNF-a variations for intracranial aneurysm in Japanese population.
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Academic Article
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Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
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Academic Article
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Common variation in GPC5 is associated with acquired nephrotic syndrome.
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Academic Article
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Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
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Academic Article
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Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy.
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Academic Article
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Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
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Academic Article
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Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.
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Academic Article
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Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.
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Academic Article
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ADAM8 as a novel serological and histochemical marker for lung cancer.
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Academic Article
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Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
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Academic Article
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Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese.
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Academic Article
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A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
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Academic Article
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Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials.
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Academic Article
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A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
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Academic Article
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Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
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Academic Article
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Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
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Academic Article
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A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
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Academic Article
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Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
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Academic Article
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Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
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Academic Article
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Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
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Academic Article
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New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.
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Academic Article
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A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
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Academic Article
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A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
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Academic Article
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Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
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Academic Article
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Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients.
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Academic Article
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A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
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Academic Article
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A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.
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Academic Article
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A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
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Academic Article
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A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
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Academic Article
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Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.
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Academic Article
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Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.
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Academic Article
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Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese.
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Academic Article
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Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
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Academic Article
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Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer.
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Academic Article
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Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
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Academic Article
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SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis.
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Academic Article
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Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.
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Academic Article
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Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.
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Academic Article
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IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
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Academic Article
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Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level.
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Academic Article
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Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma.
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Academic Article
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Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis.
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Academic Article
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Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy.
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Academic Article
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Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
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Academic Article
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Lack of association between variations of PDE4D and ischemic stroke in the Japanese population.
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Academic Article
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Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1.
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Academic Article
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Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
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Academic Article
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Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
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Academic Article
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IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.
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Academic Article
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A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
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Academic Article
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HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
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Academic Article
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Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer.
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Academic Article
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A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.
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Academic Article
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A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
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Academic Article
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Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.
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Academic Article
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Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy.
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Academic Article
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Nucleotide pyrophosphatase gene polymorphism associated with ossification of the posterior longitudinal ligament of the spine.
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Academic Article
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Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
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Academic Article
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Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
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Academic Article
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Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
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Academic Article
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Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: identification of genes associated with progression and metastasis.
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Academic Article
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Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas.
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Academic Article
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Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
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Academic Article
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[A phase I study of combination-therapy with gemcitabine and epitope peptides derived from human vascular endothelial growth factor receptor for unresectable or recurrent pancreas cancer].
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Academic Article
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Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
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Academic Article
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Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
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Academic Article
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Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.
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Academic Article
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Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
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Academic Article
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Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.
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Academic Article
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A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
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Academic Article
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Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
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Academic Article
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Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
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Academic Article
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A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
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Academic Article
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Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
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Academic Article
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Serum REG4 level is a predictive biomarker for the response to preoperative chemoradiotherapy in patients with pancreatic cancer.
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Academic Article
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Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.
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Academic Article
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Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
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Academic Article
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An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
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Academic Article
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Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
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Academic Article
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Impact of four loci on serum tamsulosin hydrochloride concentration.
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Academic Article
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High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
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Academic Article
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Variations in the FTO gene are associated with severe obesity in the Japanese.
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Academic Article
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PKIB expression strongly correlated with phosphorylated Akt expression in breast cancers and also with triple-negative breast cancer subtype.
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Academic Article
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Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.
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Academic Article
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INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
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Academic Article
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Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
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Academic Article
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Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
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Academic Article
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A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
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Academic Article
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Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
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Academic Article
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Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
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Academic Article
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Impact of PSCA variation on gastric ulcer susceptibility.
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Academic Article
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Genome-wide gene expression profiles of clear cell renal cell carcinoma: identification of molecular targets for treatment of renal cell carcinoma.
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Academic Article
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Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
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Academic Article
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Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
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Academic Article
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Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays.
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Academic Article
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Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
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Academic Article
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ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.
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Academic Article
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HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy.
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Academic Article
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A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
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Academic Article
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TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
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Academic Article
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Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese.
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Academic Article
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Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.
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Academic Article
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Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.
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Academic Article
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Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population.
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Academic Article
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Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
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Academic Article
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Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.
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Academic Article
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Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
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Academic Article
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Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
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Academic Article
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An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
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Academic Article
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Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
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Academic Article
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Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
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Academic Article
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A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population.
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Academic Article
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Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy.
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Academic Article
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Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
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Academic Article
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Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population.
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Academic Article
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Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
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Academic Article
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Comparison of gene expression profiles between Opisthorchis viverrini and non-Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma.
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Academic Article
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Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.
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Academic Article
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Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
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Academic Article
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Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
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Academic Article
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Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.
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Academic Article
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Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
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Academic Article
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Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma.
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Academic Article
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Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).
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Academic Article
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Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
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Academic Article
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Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy.
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Academic Article
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RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.
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Academic Article
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Colorectal cancer metastasis to the thyroid.
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Academic Article
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A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
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Academic Article
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Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
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Academic Article
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Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor.
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Academic Article
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Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition.
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Academic Article
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Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
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Academic Article
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Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer.
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Academic Article
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A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.
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Academic Article
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Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.
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Academic Article
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Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas.
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Academic Article
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Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
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Academic Article
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Genetic polymorphisms in the IL22 gene are associated with psoriasis vulgaris in a Japanese population.
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Academic Article
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[Phase I study of combination therapy with peptide vaccine and anti-cancer drug for colorectal cancer].
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Academic Article
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Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
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Academic Article
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Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma.
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Academic Article
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Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
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Academic Article
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Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers.
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Academic Article
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Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
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Academic Article
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Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes.
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Academic Article
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A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
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Academic Article
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Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.
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Academic Article
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A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
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Academic Article
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A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
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Academic Article
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Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
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Academic Article
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A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
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Academic Article
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Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
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Academic Article
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Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.
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Academic Article
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Plasma low-molecular-weight proteome profiling identified neuropeptide-Y as a prostate cancer biomarker polypeptide.
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Academic Article
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Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
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Academic Article
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A functional polymorphism in IL-18 is associated with severity of bronchial asthma.
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Academic Article
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Tumor budding is a significant indicator of a poor prognosis in lung squamous cell carcinoma patients.
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Academic Article
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Prediction of response to imatinib by cDNA microarray analysis.
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Academic Article
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Genome-wide association study of breast cancer in the Japanese population.
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Academic Article
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Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
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Academic Article
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Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
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Academic Article
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Prevalence of allergic rhinitis and sensitization to common aeroallergens in a Japanese population.
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Academic Article
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[S-1/CDDP combined neoadjuvant chemotherapy and surgical resection for advanced gastric cancer. Analysis of 12 patients with lymph node metastasis in Saitama Red Cross Hospital].
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Academic Article
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Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
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Academic Article
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Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer.
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Academic Article
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Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
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Academic Article
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MRG-binding protein contributes to colorectal cancer development.
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Academic Article
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IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C.
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Academic Article
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Enhanced SMYD3 expression is essential for the growth of breast cancer cells.
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Academic Article
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Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
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Academic Article
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ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
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Academic Article
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A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
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Academic Article
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Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
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Academic Article
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Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
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Academic Article
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Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.
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Academic Article
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A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.
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Academic Article
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A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
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Academic Article
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Detection of novel cancer-testis antigen-specific T-cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carcinoma.
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Academic Article
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A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
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Academic Article
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Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
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Academic Article
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Prediction of outcome of advanced cervical cancer to thermoradiotherapy according to expression profiles of 35 genes selected by cDNA microarray analysis.
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Academic Article
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Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix.
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Academic Article
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Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.
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Academic Article
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Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers.
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Academic Article
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A phase ?I study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study).
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Academic Article
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Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
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Academic Article
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Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
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Academic Article
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Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients.
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Academic Article
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Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy.
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Academic Article
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Germline PARP4 mutations in patients with primary thyroid and breast cancers.
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Academic Article
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Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
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Academic Article
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Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
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Academic Article
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Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
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Academic Article
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Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer.
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Lobectomy of pulmonary metastasis of endometrial stromal sarcoma.
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Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation.
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Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
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Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.
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Recurrence in regional pulmonary lymph nodes after surgery for isolated pulmonary metastasis from hepatocellular carcinoma.
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Lobectomy of second primary cancer in survivor of small cell lung cancer with brain metastasis.
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Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations.
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Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors.
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Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy.
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Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
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Myasthenic crisis and polymyositis induced by one dose of nivolumab.
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[A case with an ovarian cancer patient who could receive anti-cancer therapy and palliative care simultaneously at home through seamless collaboration in healthcare linkage].
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Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
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Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells.
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Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma.
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Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
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Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study.
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Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study.
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T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
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Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project.
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Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
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Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan.
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Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection.
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Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases.
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Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan.
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Statin use and all-cause and cancer mortality: BioBank Japan cohort.
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Overview of the BioBank Japan Project: Study design and profile.
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Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project.
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Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer.
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Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project.
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Characteristics of patients with liver cancer in the BioBank Japan project.
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Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project.
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Tracheal Bronchus: Beware of Anomalous Venous Drainage!
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Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project.
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Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
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Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort.
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Clinical and histopathological characteristics of patients with prostate cancer in the BioBank Japan project.
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Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.
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Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
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SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
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Case of malignant melanoma that developed the ability to secrete granulocyte colony-stimulating factor.
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Phase I clinical trial of cell division associated 1 (CDCA1) peptide vaccination for castration resistant prostate cancer.
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[A case of inoperable gastric small cell carcinoma effectively treated by chemotherapy and radiotherapy].
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Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients.
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The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
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A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
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Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.
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Phase I Study of Multiple Epitope Peptide Vaccination in Patients With Recurrent or Persistent Cervical Cancer.
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GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
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Free-floating cancer cells in lymph node sinuses of hilar lymph node-positive patients with non-small cell lung cancer.
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A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients.
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Diagnostic utility and pitfalls of intraoperative pulmonary imprint cytology based on final pathological diagnoses.
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Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
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Significant differences in T cell receptor repertoires in lung adenocarcinomas with and without epidermal growth factor receptor mutations.
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A biosafety algorithm for the protection of pathology staff during intraoperative examinations of pulmonary lesions.
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Immune profiles in primary squamous cell carcinoma of the head and neck.
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Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients.
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Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
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Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.
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Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy.
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Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?
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Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites.
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CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
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Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects.
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High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo.
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Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer.
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Neoantigens elicit T cell responses in breast cancer.
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Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis.
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Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer.
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