| Item Type | Name |
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Concept
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Apoptosis
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Concept
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Apoptosis Regulatory Proteins
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Concept
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TNF-Related Apoptosis-Inducing Ligand
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Academic Article
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A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
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Academic Article
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Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
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Academic Article
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Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53.
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Academic Article
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MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
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Academic Article
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Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
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Academic Article
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Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
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Academic Article
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Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia.
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Academic Article
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Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
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Academic Article
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Maturational sequence of neuroblastoma revealed by molecular analysis on cDNA microarrays.
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Academic Article
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p53AIP1 regulates the mitochondrial apoptotic pathway.
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Academic Article
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Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
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Academic Article
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Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
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Academic Article
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WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
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Academic Article
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Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.
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Academic Article
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p53RDL1 regulates p53-dependent apoptosis.
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Academic Article
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Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
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Academic Article
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Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
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Academic Article
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Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
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Academic Article
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Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
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Academic Article
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EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.
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Academic Article
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Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.
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Academic Article
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Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
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Academic Article
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Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
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Academic Article
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Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.
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Academic Article
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Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
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Academic Article
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The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
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Academic Article
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Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.
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Academic Article
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Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1.
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Academic Article
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Prediction of outcome of advanced cervical cancer to thermoradiotherapy according to expression profiles of 35 genes selected by cDNA microarray analysis.
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Academic Article
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Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
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Academic Article
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Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
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Academic Article
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Isolation of a novel gene, CABC1, encoding a mitochondrial protein that is highly homologous to yeast activity of bc1 complex.
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Academic Article
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Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
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Academic Article
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Isolation of p53-target genes and their functional analysis.
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Academic Article
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Herpes simplex virus-induced, death receptor-dependent apoptosis and regression of transplanted human cancers.
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Academic Article
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Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
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Academic Article
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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
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Academic Article
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Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
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Academic Article
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GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
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Academic Article
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Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.
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Academic Article
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Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
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Academic Article
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MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
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Academic Article
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Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
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Academic Article
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WHSC1 monomethylates histone H1 and induces stem-cell like features in squamous cell carcinoma of the head and neck.
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