Item Type | Name |
Concept
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Genetic Association Studies
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Concept
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Genome-Wide Association Study
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Academic Article
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Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.
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Academic Article
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Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients.
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Academic Article
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Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
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Academic Article
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Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
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Academic Article
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Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia.
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Academic Article
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Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
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Academic Article
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Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies.
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Academic Article
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A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma.
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Academic Article
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Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
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Academic Article
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Making a haplotype catalog with estimated frequencies based on SNP homozygotes.
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Academic Article
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Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
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Academic Article
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Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
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Academic Article
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Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
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Academic Article
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The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
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Academic Article
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Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
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Academic Article
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Genome-wide association study of intracranial aneurysm identifies three new risk loci.
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Academic Article
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Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand.
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Academic Article
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Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
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Academic Article
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Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
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Academic Article
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A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
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Academic Article
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Establishment of a standardized system to perform population structure analyses with limited sample size or with different sets of SNP genotypes.
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Academic Article
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Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
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Academic Article
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Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
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Academic Article
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A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
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Academic Article
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Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
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Academic Article
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Common variation in GPC5 is associated with acquired nephrotic syndrome.
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Academic Article
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Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
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Academic Article
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Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
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Academic Article
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A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
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Academic Article
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SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
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Academic Article
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Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.
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Academic Article
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Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
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Academic Article
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Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese.
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Academic Article
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A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
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Academic Article
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Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis.
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Academic Article
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Genome-wide association study of epirubicin-induced leukopenia in Japanese patients.
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Academic Article
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Genome-wide association meta-analysis identifies new endometriosis risk loci.
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Academic Article
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Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
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Academic Article
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A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
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Academic Article
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Evaluating genetic risk for prostate cancer among Japanese and Latinos.
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Academic Article
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A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
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Academic Article
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A genome-wide association study identifies three new risk loci for Kawasaki disease.
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Academic Article
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Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
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Academic Article
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SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
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Academic Article
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Multiple loci are associated with white blood cell phenotypes.
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Academic Article
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Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
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Academic Article
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Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.
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Academic Article
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New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.
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Academic Article
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A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
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Academic Article
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Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response.
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Academic Article
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A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
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Academic Article
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Meta-analysis identifies common variants associated with body mass index in east Asians.
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Academic Article
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A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis.
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Academic Article
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A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
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Academic Article
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Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing.
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Academic Article
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A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
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Academic Article
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Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.
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Academic Article
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Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
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Academic Article
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Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.
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Academic Article
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PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
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Academic Article
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A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
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Academic Article
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A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.
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Academic Article
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Prostate cancer genomics, biology, and risk assessment through genome-wide association studies.
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Academic Article
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A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
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Academic Article
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A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
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Academic Article
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Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
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Academic Article
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Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.
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Academic Article
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Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes.
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Academic Article
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A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
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Academic Article
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Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
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Academic Article
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Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
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Academic Article
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Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.
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Academic Article
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Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.
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Academic Article
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Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
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Academic Article
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Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.
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Academic Article
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Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
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Academic Article
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A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.
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Academic Article
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Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
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Academic Article
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Functional variants in NFKBIE and RTKN2 involved in activation of the NF-?B pathway are associated with rheumatoid arthritis in Japanese.
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Academic Article
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High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population.
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Academic Article
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Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
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Academic Article
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Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.
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Academic Article
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Genome-wide association study of hematological and biochemical traits in a Japanese population.
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Academic Article
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A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
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Academic Article
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A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.
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Academic Article
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Replication study for the association between four Loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes.
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Academic Article
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Genome-wide association study of pancreatic cancer in Japanese population.
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Academic Article
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Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).
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Academic Article
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Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.
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Academic Article
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Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
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Academic Article
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Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.
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Academic Article
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Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population.
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Academic Article
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Lack of association between variations of PDE4D and ischemic stroke in the Japanese population.
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Academic Article
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A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.
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Academic Article
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Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
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Academic Article
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Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
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Academic Article
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Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.
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Academic Article
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A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
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Academic Article
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HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
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Academic Article
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A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
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Academic Article
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Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
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Academic Article
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Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
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Academic Article
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A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.
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Academic Article
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A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
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Academic Article
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Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
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Academic Article
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Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.
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Academic Article
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Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
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Academic Article
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Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy.
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Academic Article
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Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
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Academic Article
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Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
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Academic Article
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A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
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Academic Article
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Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
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Academic Article
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Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
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Academic Article
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A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
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Academic Article
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Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
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Academic Article
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Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
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Academic Article
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Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
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Academic Article
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Impact of four loci on serum tamsulosin hydrochloride concentration.
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Academic Article
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High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
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Academic Article
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Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
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Academic Article
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Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.
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Academic Article
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Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
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Academic Article
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A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
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Academic Article
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Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
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Academic Article
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Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
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Academic Article
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Impact of PSCA variation on gastric ulcer susceptibility.
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Academic Article
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Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
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Academic Article
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Genome wide association study of age at menarche in the Japanese population.
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Academic Article
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Association of the RIP2 gene with childhood atopic asthma.
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Academic Article
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Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
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Academic Article
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Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.
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Academic Article
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ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.
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Academic Article
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A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
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Academic Article
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TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
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Academic Article
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Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.
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Academic Article
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High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
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Academic Article
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Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
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Academic Article
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Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population.
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Academic Article
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The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
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Academic Article
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Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
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Academic Article
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Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
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Academic Article
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An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
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Academic Article
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Seven new loci associated with age-related macular degeneration.
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Academic Article
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Pathway analysis of genome-wide data improves warfarin dose prediction.
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Academic Article
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Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
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Academic Article
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Trans-ethnic meta-analysis of white blood cell phenotypes.
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Academic Article
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A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population.
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Academic Article
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New gene functions in megakaryopoiesis and platelet formation.
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Academic Article
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Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
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Academic Article
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Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
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Academic Article
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Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease.
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Academic Article
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Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
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Academic Article
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DNA variations in human and medical genetics: 25 years of my experience.
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Academic Article
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Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population.
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Academic Article
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Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
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Academic Article
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Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.
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Academic Article
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Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
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Academic Article
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Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes.
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Academic Article
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Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.
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Academic Article
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A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
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Academic Article
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Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
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Academic Article
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Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
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Academic Article
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Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
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Academic Article
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Genome-wide association study of breast cancer in the Japanese population.
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Academic Article
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No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.
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Academic Article
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Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
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Academic Article
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Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
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Academic Article
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Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
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Academic Article
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HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
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Academic Article
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The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort.
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Academic Article
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Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
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Academic Article
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VAV3 mediates resistance to breast cancer endocrine therapy.
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Academic Article
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HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese.
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Academic Article
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A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
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Academic Article
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Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
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Academic Article
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A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
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Academic Article
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Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix.
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Academic Article
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Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.
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Academic Article
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New correction algorithms for multiple comparisons in case-control multilocus association studies based on haplotypes and diplotype configurations.
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Academic Article
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An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway.
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Academic Article
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Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP Maps, of 199 drug-related genes in 752 subjects: the analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs.
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Academic Article
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Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
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Academic Article
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Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.
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Academic Article
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Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
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Academic Article
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Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
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Academic Article
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Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
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Academic Article
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Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
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Academic Article
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Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
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Academic Article
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SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
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Academic Article
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The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
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Academic Article
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Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
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Academic Article
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Breast cancer: The translation of big genomic data to cancer precision medicine.
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Academic Article
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Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
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Academic Article
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Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population.
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Academic Article
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Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.
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Academic Article
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Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
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Academic Article
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A cross-population atlas of genetic associations for 220 human phenotypes.
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Academic Article
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Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension.
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