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Nakamura, Yusuke
One or more keywords matched the following items that are connected to Nakamura, Yusuke
Item TypeName
Concept DNA Damage
Concept DNA-Binding Proteins
Concept DNA, Mitochondrial
Concept DNA, Ribosomal
Concept DNA Repair
Concept DNA Mutational Analysis
Concept DNA, Neoplasm
Concept DNA
Concept DNA Polymerase III
Concept DNA Replication
Concept DNA, Viral
Concept DNA Fingerprinting
Concept DNA Modification Methylases
Concept DNA, Antisense
Concept DNA Probes
Concept Sequence Analysis, DNA
Concept DNA, Complementary
Concept DNA Breaks, Double-Stranded
Concept DNA Fragmentation
Concept DNA Copy Number Variations
Concept DNA Methylation
Concept DNA Mismatch Repair
Concept DNA Helicases
Concept DNA Primers
Academic Article The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
Academic Article Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs.
Academic Article Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
Academic Article Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
Academic Article Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Academic Article Predicting response to docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
Academic Article Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
Academic Article Criterion values for multiplex SNP genotyping by the invader assay.
Academic Article Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression.
Academic Article Automated SNPs typing system based on the Invader assay.
Academic Article The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
Academic Article Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.
Academic Article Common variation in GPC5 is associated with acquired nephrotic syndrome.
Academic Article Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese.
Academic Article New pharmacogenetic test for detecting an HLA-A*31: 01 allele using the InvaderPlus assay.
Academic Article Physical localization of 70 polymorphic markers to human chromosome 5 by fluorescence in situ hybridization.
Academic Article PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
Academic Article A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
Academic Article CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection.
Academic Article A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
Academic Article Replication study for the association between four Loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes.
Academic Article Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).
Academic Article Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis.
Academic Article Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
Academic Article Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
Academic Article Development of new HLA-B*3505 genotyping method using Invader assay.
Academic Article Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
Academic Article Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray.
Academic Article Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
Academic Article Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.
Academic Article Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
Academic Article Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors.
Academic Article Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas.
Academic Article Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
Academic Article Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
Academic Article Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.
Academic Article Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes.
Academic Article Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene.
Academic Article Functional haplotypes of IL-12B are associated with childhood atopic asthma.
Academic Article Identification of 156 novel SNPs in 29 genes encoding G-protein coupled receptors.
Academic Article Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
Academic Article Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
Academic Article Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro.
Academic Article Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
Academic Article An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
Academic Article Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
Academic Article Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
Academic Article Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
Academic Article C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
Academic Article Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
Academic Article Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
Academic Article Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
Academic Article Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
Academic Article Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
Academic Article Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
Academic Article Identification of CAG repeat-containing genes expressed in human brain as candidate genes for autosomal dominant spinocerebellar ataxias and other neurodegenerative diseases.
Academic Article Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
Academic Article Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
Academic Article Cyclin K as a direct transcriptional target of the p53 tumor suppressor.
Academic Article Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.
Academic Article Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
Academic Article Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
Academic Article p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
Academic Article Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
Academic Article Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
Academic Article Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8.
Academic Article Maturational sequence of neuroblastoma revealed by molecular analysis on cDNA microarrays.
Academic Article CD40 ligand gene and Kawasaki disease.
Academic Article Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
Academic Article Catalog of 238 variations among six human genes encoding solute carriers ( hSLCs) in the Japanese population.
Academic Article Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
Academic Article ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
Academic Article DNA variations in human and medical genetics: 25 years of my experience.
Academic Article Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.
Academic Article Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomas.
Academic Article 906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.
Academic Article A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
Academic Article Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
Academic Article p53RDL1 regulates p53-dependent apoptosis.
Academic Article A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
Academic Article Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
Academic Article Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
Academic Article Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
Academic Article Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
Academic Article Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
Academic Article Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.
Academic Article Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.
Academic Article Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma.
Academic Article Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface.
Academic Article Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
Academic Article Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
Academic Article Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
Academic Article PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
Academic Article Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
Academic Article Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Academic Article Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs).
Academic Article Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
Academic Article Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
Academic Article Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
Academic Article Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
Academic Article WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
Academic Article hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
Academic Article Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.
Academic Article The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
Academic Article EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.
Academic Article Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
Academic Article Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.
Academic Article Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
Academic Article Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Academic Article The BioBank Japan Project.
Academic Article High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.
Academic Article Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
Academic Article Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
Academic Article Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
Academic Article Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
Academic Article Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
Academic Article [BioBank Japan project].
Academic Article Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
Academic Article Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
Academic Article Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
Academic Article Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
Academic Article The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Academic Article Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
Academic Article The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells.
Academic Article A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability.
Academic Article A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
Academic Article Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Academic Article Population-genetic nature of copy number variations in the human genome.
Academic Article Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.
Academic Article The p53 family member genes are involved in the Notch signal pathway.
Academic Article A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
Academic Article Identification of semaphorin3B as a direct target of p53.
Academic Article Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
Academic Article Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix.
Academic Article The DNA binding site specificity and antiproliferative property of ternary Pt(II) and Zn(II) complexes of phenanthroline and N,N'-ethylenediaminediacetic acid.
Academic Article Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
Academic Article Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
Academic Article SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
Academic Article Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus.
Academic Article International network of cancer genome projects.
Academic Article Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.
Academic Article Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
Academic Article Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
Academic Article DNA micropatterning on polycrystalline diamond via one-step direct amination.
Academic Article Catalog of 77 single-nucleotide polymorphisms (SNPs) in the carbohydrate sulfotransferase 1 (CHST1) and carbohydrate sulfotransferase 3 (CHST3) genes.
Academic Article Isolation of a novel gene, CABC1, encoding a mitochondrial protein that is highly homologous to yeast activity of bc1 complex.
Academic Article Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues.
Academic Article Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
Academic Article Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
Academic Article Re: Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA.
Academic Article Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
Academic Article Regulation of iron homeostasis by the p53-ISCU pathway.
Academic Article Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
Academic Article Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
Academic Article Isolation of p53-target genes and their functional analysis.
Academic Article Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
Academic Article Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins.
Academic Article Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy.
Academic Article Construction and characterization of a vestibular-specific cDNA library using T7-based RNA amplification.
Academic Article Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors.
Academic Article HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.
Academic Article Accurate automated clustering of two-dimensional data for single-nucleotide polymorphism genotyping by a combination of clustering methods: evaluation by large-scale real data.
Academic Article WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
Academic Article WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
Academic Article The Transcriptional Landscape of p53 Signalling Pathway.
Academic Article A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
Academic Article Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
Academic Article Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?
Academic Article CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
Academic Article Detection of circulating tumor DNA in patients of operative colorectal and gastric cancers.
Academic Article Clinicopathologic significance of protein lysine methyltransferases in cancer.
Academic Article Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer.
Academic Article Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome.
Academic Article Clinical implementation and current advancement of blood liquid biopsy in cancer.
Academic Article Serial circulating tumor DNA monitoring of CDK4/6 inhibitors response in metastatic breast cancer.
Academic Article Rapid genomic profiling of circulating tumor DNA in non-small cell lung cancer using Oncomine Precision Assay with Genexus™ integrated sequencer.
Academic Article Tumor-Informed Approach Improved ctDNA Detection Rate in Resected Pancreatic Cancer.
Academic Article Tumor-informed or tumor-agnostic circulating tumor DNA as a biomarker for risk of recurrence in resected colorectal cancer patients.
Concept Circulating Tumor DNA
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