Item Type | Name |
Concept
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DNA Damage
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Concept
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DNA-Binding Proteins
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Concept
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DNA, Mitochondrial
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Concept
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DNA, Ribosomal
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Concept
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DNA Repair
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Concept
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DNA Mutational Analysis
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Concept
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DNA, Neoplasm
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Concept
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DNA
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Concept
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DNA Polymerase III
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Concept
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DNA Replication
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Concept
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DNA, Viral
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Concept
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DNA Fingerprinting
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Concept
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DNA Modification Methylases
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Concept
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DNA, Antisense
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Concept
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DNA Probes
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Concept
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Sequence Analysis, DNA
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Concept
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DNA, Complementary
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Concept
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DNA Breaks, Double-Stranded
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Concept
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DNA Fragmentation
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Concept
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DNA Copy Number Variations
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Concept
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DNA Methylation
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Concept
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DNA Mismatch Repair
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Concept
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DNA Helicases
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Concept
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DNA Primers
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Academic Article
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The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
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Academic Article
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Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs.
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Academic Article
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Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
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Academic Article
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Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
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Academic Article
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Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
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Academic Article
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Predicting response to docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling.
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Academic Article
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Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
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Academic Article
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Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
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Academic Article
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Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
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Academic Article
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Criterion values for multiplex SNP genotyping by the invader assay.
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Academic Article
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Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression.
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Academic Article
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Automated SNPs typing system based on the Invader assay.
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Academic Article
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The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
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Academic Article
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Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.
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Academic Article
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Common variation in GPC5 is associated with acquired nephrotic syndrome.
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Academic Article
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Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese.
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Academic Article
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New pharmacogenetic test for detecting an HLA-A*31: 01 allele using the InvaderPlus assay.
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Academic Article
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Physical localization of 70 polymorphic markers to human chromosome 5 by fluorescence in situ hybridization.
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Academic Article
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PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
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Academic Article
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A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
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Academic Article
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CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection.
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Academic Article
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A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
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Academic Article
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Replication study for the association between four Loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes.
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Academic Article
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Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).
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Academic Article
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Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis.
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Academic Article
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Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
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Academic Article
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Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
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Academic Article
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Development of new HLA-B*3505 genotyping method using Invader assay.
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Academic Article
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Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
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Academic Article
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Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray.
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Academic Article
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Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
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Academic Article
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Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.
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Academic Article
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Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
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Academic Article
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Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors.
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Academic Article
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Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas.
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Academic Article
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Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
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Academic Article
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Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
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Academic Article
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Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.
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Academic Article
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Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes.
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Academic Article
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Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene.
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Academic Article
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Functional haplotypes of IL-12B are associated with childhood atopic asthma.
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Academic Article
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Identification of 156 novel SNPs in 29 genes encoding G-protein coupled receptors.
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Academic Article
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Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
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Academic Article
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Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
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Academic Article
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Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro.
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Academic Article
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Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
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Academic Article
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An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
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Academic Article
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Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
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Academic Article
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Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
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Academic Article
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Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
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Academic Article
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C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
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Academic Article
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Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
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Academic Article
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Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
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Academic Article
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Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
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Academic Article
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Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
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Academic Article
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Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
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Academic Article
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Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
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Academic Article
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Identification of CAG repeat-containing genes expressed in human brain as candidate genes for autosomal dominant spinocerebellar ataxias and other neurodegenerative diseases.
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Academic Article
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Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
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Academic Article
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Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
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Academic Article
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Cyclin K as a direct transcriptional target of the p53 tumor suppressor.
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Academic Article
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Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.
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Academic Article
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Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
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Academic Article
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Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
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Academic Article
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p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
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Academic Article
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Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
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Academic Article
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Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
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Academic Article
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Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8.
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Academic Article
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Maturational sequence of neuroblastoma revealed by molecular analysis on cDNA microarrays.
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Academic Article
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CD40 ligand gene and Kawasaki disease.
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Academic Article
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Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
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Academic Article
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Catalog of 238 variations among six human genes encoding solute carriers ( hSLCs) in the Japanese population.
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Academic Article
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Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
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Academic Article
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ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
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Academic Article
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DNA variations in human and medical genetics: 25 years of my experience.
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Academic Article
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Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.
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Academic Article
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Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomas.
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Academic Article
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906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.
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Academic Article
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A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
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Academic Article
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Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
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Academic Article
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p53RDL1 regulates p53-dependent apoptosis.
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Academic Article
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A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
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Academic Article
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Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
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Academic Article
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Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
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Academic Article
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Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
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Academic Article
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Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
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Academic Article
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Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
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Academic Article
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Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.
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Academic Article
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Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.
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Academic Article
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Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma.
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Academic Article
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Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface.
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Academic Article
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Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
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Academic Article
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Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
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Academic Article
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Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
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Academic Article
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PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
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Academic Article
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Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
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Academic Article
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Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
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Academic Article
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Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs).
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Academic Article
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Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
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Academic Article
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Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
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Academic Article
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Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
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Academic Article
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Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
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Academic Article
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WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
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Academic Article
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hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
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Academic Article
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Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.
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Academic Article
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The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
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Academic Article
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EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.
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Academic Article
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Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
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Academic Article
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Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.
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Academic Article
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Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
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Academic Article
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Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
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Academic Article
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The BioBank Japan Project.
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Academic Article
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High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.
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Academic Article
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Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
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Academic Article
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Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
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Academic Article
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Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
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Academic Article
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Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
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Academic Article
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Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
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Academic Article
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[BioBank Japan project].
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Academic Article
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Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
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Academic Article
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Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
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Academic Article
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Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
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Academic Article
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Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
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Academic Article
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The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
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Academic Article
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Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
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Academic Article
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The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells.
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Academic Article
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A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability.
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Academic Article
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A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
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Academic Article
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Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
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Academic Article
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Population-genetic nature of copy number variations in the human genome.
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Academic Article
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Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.
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Academic Article
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The p53 family member genes are involved in the Notch signal pathway.
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Academic Article
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A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
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Academic Article
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Identification of semaphorin3B as a direct target of p53.
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Academic Article
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Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
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Academic Article
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Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix.
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Academic Article
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The DNA binding site specificity and antiproliferative property of ternary Pt(II) and Zn(II) complexes of phenanthroline and N,N'-ethylenediaminediacetic acid.
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Academic Article
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Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
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Academic Article
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Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
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Academic Article
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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
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Academic Article
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Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus.
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Academic Article
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International network of cancer genome projects.
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Academic Article
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Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.
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Academic Article
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Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
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Academic Article
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Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
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Academic Article
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DNA micropatterning on polycrystalline diamond via one-step direct amination.
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Academic Article
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Catalog of 77 single-nucleotide polymorphisms (SNPs) in the carbohydrate sulfotransferase 1 (CHST1) and carbohydrate sulfotransferase 3 (CHST3) genes.
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Academic Article
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Isolation of a novel gene, CABC1, encoding a mitochondrial protein that is highly homologous to yeast activity of bc1 complex.
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Academic Article
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Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues.
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Academic Article
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Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
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Academic Article
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Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
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Academic Article
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Re: Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA.
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Academic Article
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Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
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Academic Article
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Regulation of iron homeostasis by the p53-ISCU pathway.
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Academic Article
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Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
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Academic Article
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Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
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Academic Article
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Isolation of p53-target genes and their functional analysis.
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Academic Article
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Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
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Academic Article
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Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins.
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Academic Article
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Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy.
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Academic Article
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Construction and characterization of a vestibular-specific cDNA library using T7-based RNA amplification.
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Academic Article
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Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors.
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Academic Article
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HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.
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Academic Article
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Accurate automated clustering of two-dimensional data for single-nucleotide polymorphism genotyping by a combination of clustering methods: evaluation by large-scale real data.
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Academic Article
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WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
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Academic Article
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WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
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Academic Article
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The Transcriptional Landscape of p53 Signalling Pathway.
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Academic Article
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A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
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Academic Article
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Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
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Academic Article
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Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?
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Academic Article
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CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
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Academic Article
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Detection of circulating tumor DNA in patients of operative colorectal and gastric cancers.
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Academic Article
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Clinicopathologic significance of protein lysine methyltransferases in cancer.
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Academic Article
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Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer.
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Academic Article
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Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome.
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Academic Article
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Clinical implementation and current advancement of blood liquid biopsy in cancer.
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Academic Article
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Serial circulating tumor DNA monitoring of CDK4/6 inhibitors response in metastatic breast cancer.
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Academic Article
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Rapid genomic profiling of circulating tumor DNA in non-small cell lung cancer using Oncomine Precision Assay with Genexus™ integrated sequencer.
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Academic Article
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Tumor-Informed Approach Improved ctDNA Detection Rate in Resected Pancreatic Cancer.
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Academic Article
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Tumor-informed or tumor-agnostic circulating tumor DNA as a biomarker for risk of recurrence in resected colorectal cancer patients.
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Concept
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Circulating Tumor DNA
|