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Nakamura, Yusuke
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Concept Female
Academic Article Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs.
Academic Article Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.
Academic Article Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.
Academic Article Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice.
Academic Article Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
Academic Article Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Academic Article Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
Academic Article Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
Academic Article Predicting response to docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling.
Academic Article Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
Academic Article Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.
Academic Article A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma.
Academic Article HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients.
Academic Article Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
Academic Article Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
Academic Article Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.
Academic Article Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
Academic Article Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
Academic Article The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
Academic Article HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis.
Academic Article Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
Academic Article Genome-wide association study of intracranial aneurysm identifies three new risk loci.
Academic Article Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand.
Academic Article Phase I clinical trial using peptide vaccine for human vascular endothelial growth factor receptor 2 in combination with gemcitabine for patients with advanced pancreatic cancer.
Academic Article Successful outcomes using combination therapy of interleukin-2 and interferon-alpha for renal cell carcinoma patients with lung metastasis.
Academic Article PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
Academic Article Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
Academic Article Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.
Academic Article Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
Academic Article A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
Academic Article Impact of LIMK1, MMP2 and TNF-a variations for intracranial aneurysm in Japanese population.
Academic Article Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
Academic Article Common variation in GPC5 is associated with acquired nephrotic syndrome.
Academic Article Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
Academic Article Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy.
Academic Article Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
Academic Article SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
Academic Article Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.
Academic Article Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.
Academic Article ADAM8 as a novel serological and histochemical marker for lung cancer.
Academic Article Should CYP2D6 inhibitors be administered in conjunction with tamoxifen?
Academic Article Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
Academic Article A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
Academic Article Genome-wide association study of epirubicin-induced leukopenia in Japanese patients.
Academic Article Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials.
Academic Article Genome-wide association meta-analysis identifies new endometriosis risk loci.
Academic Article A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
Academic Article Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial.
Academic Article Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
Academic Article A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
Academic Article Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
Academic Article Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
Academic Article Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
Academic Article New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor administration.
Academic Article Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response.
Academic Article A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
Academic Article A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
Academic Article Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
Academic Article Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients.
Academic Article A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
Academic Article A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.
Academic Article A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
Academic Article A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
Academic Article Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.
Academic Article Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.
Academic Article CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans.
Academic Article Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
Academic Article High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population.
Academic Article A second generation human haplotype map of over 3.1 million SNPs.
Academic Article Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer.
Academic Article Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
Academic Article SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis.
Academic Article Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.
Academic Article Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.
Academic Article A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
Academic Article IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
Academic Article Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level.
Academic Article Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.
Academic Article Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma.
Academic Article Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis.
Academic Article Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy.
Academic Article Lack of association between variations of PDE4D and ischemic stroke in the Japanese population.
Academic Article Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1.
Academic Article Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
Academic Article Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
Academic Article IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.
Academic Article A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
Academic Article HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
Academic Article Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer.
Academic Article A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.
Academic Article A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
Academic Article Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.
Academic Article Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
Academic Article Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy.
Academic Article Nucleotide pyrophosphatase gene polymorphism associated with ossification of the posterior longitudinal ligament of the spine.
Academic Article Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
Academic Article Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
Academic Article Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: identification of genes associated with progression and metastasis.
Academic Article Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas.
Academic Article [A phase I study of combination-therapy with gemcitabine and epitope peptides derived from human vascular endothelial growth factor receptor for unresectable or recurrent pancreas cancer].
Academic Article Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
Academic Article Involvement of C12orf32 overexpression in breast carcinogenesis.
Academic Article Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
Academic Article Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
Academic Article Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.
Academic Article Functional haplotypes of IL-12B are associated with childhood atopic asthma.
Academic Article A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
Academic Article Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
Academic Article Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
Academic Article Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
Academic Article Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis.
Academic Article A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
Academic Article Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
Academic Article Serum REG4 level is a predictive biomarker for the response to preoperative chemoradiotherapy in patients with pancreatic cancer.
Academic Article Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.
Academic Article Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
Academic Article Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Academic Article An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
Academic Article Common variants in CASP3 confer susceptibility to Kawasaki disease.
Academic Article Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
Academic Article Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
Academic Article Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
Academic Article Impact of four loci on serum tamsulosin hydrochloride concentration.
Academic Article High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
Academic Article Variations in the FTO gene are associated with severe obesity in the Japanese.
Academic Article PKIB expression strongly correlated with phosphorylated Akt expression in breast cancers and also with triple-negative breast cancer subtype.
Academic Article Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.
Academic Article INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
Academic Article Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
Academic Article Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
Academic Article A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
Academic Article Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Academic Article Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
Academic Article Impact of PSCA variation on gastric ulcer susceptibility.
Academic Article Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
Academic Article Genome-wide gene expression profiles of clear cell renal cell carcinoma: identification of molecular targets for treatment of renal cell carcinoma.
Academic Article A genomewide linkage analysis of Kawasaki disease: evidence for linkage to chromosome 12.
Academic Article Genome wide association study of age at menarche in the Japanese population.
Academic Article Association of the RIP2 gene with childhood atopic asthma.
Academic Article Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
Academic Article CYP2D6 genotype and tamoxifen activity: understanding interstudy variability in methodological quality.
Academic Article Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
Academic Article Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays.
Academic Article Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
Academic Article Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
Academic Article Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
Academic Article ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.
Academic Article HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy.
Academic Article Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin.
Academic Article A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
Academic Article TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
Academic Article Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.
Academic Article Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese.
Academic Article Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies.
Academic Article High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
Academic Article Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.
Academic Article Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.
Academic Article Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population.
Academic Article Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
Academic Article Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.
Academic Article Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
Academic Article Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
Academic Article Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Academic Article An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
Academic Article Seven new loci associated with age-related macular degeneration.
Academic Article Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Academic Article Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
Academic Article Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.
Academic Article A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population.
Academic Article Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy.
Academic Article Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
Academic Article Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
Academic Article The Xq22 inversion breakpoint interrupted a novel Ras-like GTPase gene in a patient with Duchenne muscular dystrophy and profound mental retardation.
Academic Article Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population.
Academic Article Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Academic Article Comparison of gene expression profiles between Opisthorchis viverrini and non-Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma.
Academic Article Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.
Academic Article Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease.
Academic Article Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
Academic Article ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
Academic Article Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
Academic Article Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.
Academic Article Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
Academic Article Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma.
Academic Article A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
Academic Article Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).
Academic Article Non-transmissible Sendai virus encoding granulocyte macrophage colony-stimulating factor is a novel and potent vector system for producing autologous tumor vaccines.
Academic Article Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
Academic Article In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy.
Academic Article Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.
Academic Article Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy.
Academic Article RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Colorectal cancer metastasis to the thyroid.
Academic Article A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
Academic Article Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
Academic Article Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population.
Academic Article Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor.
Academic Article Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition.
Academic Article Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
Academic Article Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
Academic Article Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer.
Academic Article Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.
Academic Article Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
Academic Article A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.
Academic Article Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.
Academic Article Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas.
Academic Article Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
Academic Article Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma.
Academic Article Genetic polymorphisms in the IL22 gene are associated with psoriasis vulgaris in a Japanese population.
Academic Article Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
Academic Article Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
Academic Article Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma.
Academic Article Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
Academic Article Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
Academic Article Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers.
Academic Article Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
Academic Article Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Academic Article Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
Academic Article A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
Academic Article Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.
Academic Article A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
Academic Article A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
Academic Article Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
Academic Article A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
Academic Article Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Academic Article Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.
Academic Article Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
Academic Article A functional polymorphism in IL-18 is associated with severity of bronchial asthma.
Academic Article Tumor budding is a significant indicator of a poor prognosis in lung squamous cell carcinoma patients.
Academic Article Prediction of response to imatinib by cDNA microarray analysis.
Academic Article Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
Academic Article Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
Academic Article RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation.
Academic Article Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.
Academic Article Genome-wide association study of breast cancer in the Japanese population.
Academic Article Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
Academic Article Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
Academic Article Prevalence of allergic rhinitis and sensitization to common aeroallergens in a Japanese population.
Academic Article The BioBank Japan Project.
Academic Article [S-1/CDDP combined neoadjuvant chemotherapy and surgical resection for advanced gastric cancer. Analysis of 12 patients with lymph node metastasis in Saitama Red Cross Hospital].
Academic Article Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
Academic Article Recombination rates of genes expressed in human tissues.
Academic Article Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
Academic Article Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer.
Academic Article Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
Academic Article MRG-binding protein contributes to colorectal cancer development.
Academic Article IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C.
Academic Article Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
Academic Article Enhanced SMYD3 expression is essential for the growth of breast cancer cells.
Academic Article Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
Academic Article Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus.
Academic Article ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
Academic Article A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
Academic Article Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
Academic Article Critical roles of T-LAK cell-originated protein kinase in cytokinesis.
Academic Article The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Academic Article Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
Academic Article Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.
Academic Article A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
Academic Article A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
Academic Article A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability.
Academic Article A functional polymorphism in MMP-9 is associated with childhood atopic asthma.
Academic Article Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
Academic Article Prediction of outcome of advanced cervical cancer to thermoradiotherapy according to expression profiles of 35 genes selected by cDNA microarray analysis.
Academic Article Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
Academic Article Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
Academic Article Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix.
Academic Article Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.
Academic Article Heterozygous TGFBR2 mutations in Marfan syndrome.
Academic Article Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers.
Academic Article An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway.
Academic Article Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
Academic Article A phase ?I study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study).
Academic Article PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer.
Academic Article Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues.
Academic Article Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
Academic Article Re: Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA.
Academic Article Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients.
Academic Article Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy.
Academic Article Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
Academic Article Germline PARP4 mutations in patients with primary thyroid and breast cancers.
Academic Article Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
Academic Article Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
Academic Article Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
Academic Article Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.
Academic Article Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer.
Academic Article Lobectomy of pulmonary metastasis of endometrial stromal sarcoma.
Academic Article Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation.
Academic Article Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
Academic Article Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.
Academic Article Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations.
Academic Article Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors.
Academic Article Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy.
Academic Article Deep-sequencing of the T-cell receptor repertoire in patients with haplo-cord and matched-donor transplants.
Academic Article Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
Academic Article Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
Academic Article Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.
Academic Article [A case with an ovarian cancer patient who could receive anti-cancer therapy and palliative care simultaneously at home through seamless collaboration in healthcare linkage].
Academic Article Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
Academic Article Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells.
Academic Article Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma.
Academic Article Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study.
Academic Article Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study.
Academic Article Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL).
Academic Article T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
Academic Article Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project.
Academic Article Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
Academic Article Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan.
Academic Article Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection.
Academic Article Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases.
Academic Article Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan.
Academic Article Statin use and all-cause and cancer mortality: BioBank Japan cohort.
Academic Article Overview of the BioBank Japan Project: Study design and profile.
Academic Article Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project.
Academic Article Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer.
Academic Article Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project.
Academic Article Characteristics of patients with liver cancer in the BioBank Japan project.
Academic Article Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project.
Academic Article Tracheal Bronchus: Beware of Anomalous Venous Drainage!
Academic Article Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project.
Academic Article Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
Academic Article Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
Academic Article Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort.
Academic Article Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.
Academic Article Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
Academic Article SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
Academic Article Toxic epidermal necrolysis in a child 6 months post-hematopoietic stem cell transplantation.
Academic Article Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients.
Academic Article Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor-Engineered T Cells for Ovarian Cancer.
Academic Article The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
Academic Article miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
Academic Article A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
Academic Article Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.
Academic Article Phase I Study of Multiple Epitope Peptide Vaccination in Patients With Recurrent or Persistent Cervical Cancer.
Academic Article GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
Academic Article Video-assisted segmental resection of an intrapulmonary bronchogenic cyst mimicking a middle mediastinal cystic tumor.
Academic Article Free-floating cancer cells in lymph node sinuses of hilar lymph node-positive patients with non-small cell lung cancer.
Academic Article Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy.
Academic Article A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients.
Academic Article Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells.
Academic Article Diagnostic utility and pitfalls of intraoperative pulmonary imprint cytology based on final pathological diagnoses.
Academic Article Breast cancer: The translation of big genomic data to cancer precision medicine.
Academic Article Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
Academic Article Significant differences in T cell receptor repertoires in lung adenocarcinomas with and without epidermal growth factor receptor mutations.
Academic Article A biosafety algorithm for the protection of pathology staff during intraoperative examinations of pulmonary lesions.
Academic Article Immune profiles in primary squamous cell carcinoma of the head and neck.
Academic Article Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
Academic Article Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population.
Academic Article The GALNT6-LGALS3BP axis promotes breast cancer cell growth.
Academic Article Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
Academic Article Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.
Academic Article Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens.
Academic Article Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.
Academic Article Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?
Academic Article Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites.
Academic Article CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
Academic Article Clinicopathologic significance of protein lysine methyltransferases in cancer.
Academic Article Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects.
Academic Article High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo.
Academic Article Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer.
Academic Article Anti-cancer immunotherapy using cancer-derived multiple epitope-peptides cocktail vaccination clinical studies in patients with refractory/persistent disease of uterine cervical cancer and ovarian cancer [phase 2].
Academic Article Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome.
Academic Article Neoantigens elicit T cell responses in breast cancer.
Academic Article Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis.
Academic Article Functional genomics for breast cancer drug target discovery.
Academic Article Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer.
Academic Article Serial circulating tumor DNA monitoring of CDK4/6 inhibitors response in metastatic breast cancer.
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