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Nakamura, Yusuke
One or more keywords matched the following items that are connected to Nakamura, Yusuke
Item TypeName
Concept Alleles
Concept Amino Acid Sequence
Concept Base Sequence
Concept Gene Frequency
Concept Gene Expression Regulation
Concept Genes, Dominant
Concept Genes
Concept Genes, MHC Class II
Concept Oncogenes
Concept Gene Amplification
Concept Genes, MHC Class I
Concept Multigene Family
Concept Molecular Sequence Data
Concept Repetitive Sequences, Nucleic Acid
Concept Major Histocompatibility Complex
Concept Pseudogenes
Concept Sequence Homology, Nucleic Acid
Concept Genome
Concept Sequence Homology, Amino Acid
Concept Gene Rearrangement
Concept Gene Library
Concept Gene Duplication
Concept RNA Splice Sites
Concept Genes, Tumor Suppressor
Concept Gene Products, tax
Concept Genome, Viral
Concept Gene Expression
Concept Genes, APC
Concept Genes, Reporter
Concept Consensus Sequence
Concept Gene Transfer Techniques
Concept Gene Deletion
Concept Genes, MDR
Concept Gene Regulatory Networks
Concept src Homology Domains
Concept Gene Knockout Techniques
Concept Genetic Pleiotropy
Concept Exome
Concept Gene-Environment Interaction
Concept Genes, BRCA1
Concept Gene Expression Profiling
Concept Regulatory Elements, Transcriptional
Concept Open Reading Frames
Concept Molecular Structure
Concept Genome, Human
Concept Gene Expression Regulation, Enzymologic
Concept Gene Expression Regulation, Leukemic
Concept Genes, p53
Concept Gene Silencing
Concept Gene Knockdown Techniques
Concept Gene Targeting
Concept Gene Dosage
Concept Gene Components
Concept Transcriptome
Concept Genes, Neoplasm
Concept vpr Gene Products, Human Immunodeficiency Virus
Concept Gene Expression Regulation, Neoplastic
Concept Conserved Sequence
Concept Polymorphism, Single Nucleotide
Concept Quantitative Trait Loci
Concept Genetic Loci
Concept Nucleotide Motifs
Academic Article The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
Academic Article Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs.
Academic Article An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines.
Academic Article Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs.
Academic Article Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
Academic Article Ring finger protein 43 as a new target for cancer immunotherapy.
Academic Article Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.
Academic Article Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.
Academic Article Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
Academic Article A SNP in the ABCC11 gene is the determinant of human earwax type.
Academic Article Multiplex PCR-based real-time invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions.
Academic Article Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
Academic Article Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Academic Article Genome-wide detection and characterization of positive selection in human populations.
Academic Article Predicting response to docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling.
Academic Article Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
Academic Article Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.
Academic Article Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies.
Academic Article A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
Academic Article Criterion values for multiplex SNP genotyping by the invader assay.
Academic Article Making a haplotype catalog with estimated frequencies based on SNP homozygotes.
Academic Article Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma.
Academic Article Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
Academic Article Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
Academic Article HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis.
Academic Article Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.
Academic Article A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
Academic Article Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
Academic Article Common variation in GPC5 is associated with acquired nephrotic syndrome.
Academic Article Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy.
Academic Article Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
Academic Article SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
Academic Article Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.
Academic Article Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
Academic Article Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
Academic Article SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
Academic Article Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
Academic Article Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
Academic Article Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response.
Academic Article A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
Academic Article A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
Academic Article Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.
Academic Article Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
Academic Article Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.
Academic Article A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
Academic Article Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.
Academic Article Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes.
Academic Article Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
Academic Article Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.
Academic Article Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer.
Academic Article IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.
Academic Article High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population.
Academic Article CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection.
Academic Article Genome-wide association study of hematological and biochemical traits in a Japanese population.
Academic Article A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
Academic Article IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
Academic Article Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.
Academic Article ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations.
Academic Article Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis.
Academic Article Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
Academic Article Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy.
Academic Article Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population.
Academic Article Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
Academic Article Polymorphic human insulin-responsive glucose-transporter gene on chromosome 17p13.
Academic Article IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.
Academic Article Genome-wide gene expression profiles of ovarian carcinoma: Identification of molecular targets for the treatment of ovarian carcinoma.
Academic Article Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer.
Academic Article A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
Academic Article Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.
Academic Article Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
Academic Article Nucleotide pyrophosphatase gene polymorphism associated with ossification of the posterior longitudinal ligament of the spine.
Academic Article Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray.
Academic Article Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
Academic Article Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
Academic Article Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21.
Academic Article Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.
Academic Article Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
Academic Article Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors.
Academic Article Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations.
Academic Article Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: identification of genes associated with progression and metastasis.
Academic Article Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas.
Academic Article Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
Academic Article Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais.
Academic Article Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray.
Academic Article Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
Academic Article Critical roles of mucin 1 glycosylation by transactivated polypeptide N-acetylgalactosaminyltransferase 6 in mammary carcinogenesis.
Academic Article Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
Academic Article Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray.
Academic Article Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
Academic Article Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.
Academic Article Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes.
Academic Article Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene.
Academic Article Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
Academic Article Functional haplotypes of IL-12B are associated with childhood atopic asthma.
Academic Article Identification of 156 novel SNPs in 29 genes encoding G-protein coupled receptors.
Academic Article Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
Academic Article Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
Academic Article Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles.
Academic Article Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer.
Academic Article Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
Academic Article Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis.
Academic Article A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
Academic Article Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro.
Academic Article Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.
Academic Article Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
Academic Article An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
Academic Article Common variants in CASP3 confer susceptibility to Kawasaki disease.
Academic Article EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth.
Academic Article Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs.
Academic Article Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
Academic Article Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
Academic Article Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
Academic Article Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
Academic Article High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
Academic Article Variations in the FTO gene are associated with severe obesity in the Japanese.
Academic Article C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
Academic Article INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
Academic Article Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
Academic Article Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer.
Academic Article Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Academic Article Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
Academic Article A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
Academic Article Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
Academic Article Genome-wide gene expression profiles of clear cell renal cell carcinoma: identification of molecular targets for treatment of renal cell carcinoma.
Academic Article Association of the RIP2 gene with childhood atopic asthma.
Academic Article Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
Academic Article MOCSphaser: a haplotype inference tool from a mixture of copy number variation and single nucleotide polymorphism data.
Academic Article Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
Academic Article Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
Academic Article Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
Academic Article Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.
Academic Article Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.
Academic Article Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
Academic Article Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin.
Academic Article TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
Academic Article Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
Academic Article Identification of CAG repeat-containing genes expressed in human brain as candidate genes for autosomal dominant spinocerebellar ataxias and other neurodegenerative diseases.
Academic Article Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.
Academic Article Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice.
Academic Article Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection.
Academic Article Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
Academic Article A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis.
Academic Article Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
Academic Article Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
Academic Article Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population.
Academic Article Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
Academic Article Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
Academic Article The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
Academic Article Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
Academic Article Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
Academic Article Cyclin K as a direct transcriptional target of the p53 tumor suppressor.
Academic Article Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.
Academic Article Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
Academic Article Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
Academic Article Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.
Academic Article p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
Academic Article Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
Academic Article SMYD3 interacts with HTLV-1 Tax and regulates subcellular localization of Tax.
Academic Article High-resolution SNP map in the 55-kb region containing the selectin gene family on chromosome 1q24-q25.
Academic Article Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells.
Academic Article Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy.
Academic Article New gene functions in megakaryopoiesis and platelet formation.
Academic Article Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
Academic Article Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
Academic Article The Xq22 inversion breakpoint interrupted a novel Ras-like GTPase gene in a patient with Duchenne muscular dystrophy and profound mental retardation.
Academic Article Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell.
Academic Article Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8.
Academic Article Comparison of gene expression profiles between Opisthorchis viverrini and non-Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma.
Academic Article CD40 ligand gene and Kawasaki disease.
Academic Article DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway.
Academic Article Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma.
Academic Article Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth.
Academic Article Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
Academic Article Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
Academic Article Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
Academic Article Catalog of 238 variations among six human genes encoding solute carriers ( hSLCs) in the Japanese population.
Academic Article Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.
Academic Article Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
Academic Article The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
Academic Article ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
Academic Article Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer.
Academic Article Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
Academic Article Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
Academic Article Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.
Academic Article Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomas.
Academic Article Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
Academic Article Twenty single-nucleotide polymorphisms in four genes encoding cardiac ion channels.
Academic Article 906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.
Academic Article Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma.
Academic Article A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
Academic Article Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
Academic Article Oncogenic role of NALP7 in testicular seminomas.
Academic Article Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.
Academic Article Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
Academic Article WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
Academic Article Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy.
Academic Article RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Host molecular defense mechanisms against Chlamydophila pneumoniae and genetic studies of immune-response-related genes in asthma.
Academic Article Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.
Academic Article Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.
Academic Article Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
Academic Article Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
Academic Article Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition.
Academic Article Expression profiles of two types of human knee-joint cartilage.
Academic Article Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
Academic Article High-density SNP map of human ITR, a gene associated with vascular remodeling.
Academic Article Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
Academic Article Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
Academic Article Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.
Academic Article Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.
Academic Article Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism.
Academic Article Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma.
Academic Article Genetic polymorphisms in the IL22 gene are associated with psoriasis vulgaris in a Japanese population.
Academic Article Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface.
Academic Article Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
Academic Article Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
Academic Article Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma.
Academic Article CLCA2 as a p53-inducible senescence mediator.
Academic Article Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
Academic Article Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
Academic Article PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
Academic Article Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
Academic Article Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes.
Academic Article Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs).
Academic Article Analysis of gene-expression profiles after gamma irradiation of normal human fibroblasts.
Academic Article Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.
Academic Article A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
Academic Article Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
Academic Article Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
Academic Article WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
Academic Article Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
Academic Article hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
Academic Article Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.
Academic Article Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.
Academic Article The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
Academic Article Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
Academic Article Prediction of response to imatinib by cDNA microarray analysis.
Academic Article A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.
Academic Article Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
Academic Article Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
Academic Article RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation.
Academic Article Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.
Academic Article Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
Academic Article Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
Academic Article Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Academic Article High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.
Academic Article Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
Academic Article Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
Academic Article Recombination rates of genes expressed in human tissues.
Academic Article Japanese single nucleotide polymorphism database for 267 possible drug-related genes.
Academic Article The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.
Academic Article Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
Academic Article Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
Academic Article Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer.
Academic Article MRG-binding protein contributes to colorectal cancer development.
Academic Article Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
Academic Article Enhanced SMYD3 expression is essential for the growth of breast cancer cells.
Academic Article Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
Academic Article Identification of an HLA-A2-restricted epitope peptide derived from hypoxia-inducible protein 2 (HIG2).
Academic Article Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.
Academic Article HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
Academic Article Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
Academic Article Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
Academic Article Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
Academic Article Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
Academic Article Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
Academic Article Expression profiles of metastatic brain tumor from lung adenocarcinomas on cDNA microarray.
Academic Article The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Academic Article Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
Academic Article Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
Academic Article Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
Academic Article The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Academic Article Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
Academic Article Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.
Academic Article Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1.
Academic Article A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
Academic Article Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Academic Article Population-genetic nature of copy number variations in the human genome.
Academic Article Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
Academic Article Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.
Academic Article Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.
Academic Article A functional polymorphism in MMP-9 is associated with childhood atopic asthma.
Academic Article The p53 family member genes are involved in the Notch signal pathway.
Academic Article A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
Academic Article Identification of semaphorin3B as a direct target of p53.
Academic Article Prediction of outcome of advanced cervical cancer to thermoradiotherapy according to expression profiles of 35 genes selected by cDNA microarray analysis.
Academic Article Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
Academic Article Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
Academic Article Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix.
Academic Article A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.
Academic Article Variation of gene-based SNPs and linkage disequilibrium patterns in the human genome.
Academic Article Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas.
Academic Article Functional impact of IgA nephropathy-associated selectin gene haplotype on leukocyte-endothelial interaction.
Academic Article Gene expression profiles of small-cell lung cancers: molecular signatures of lung cancer.
Academic Article The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
Academic Article Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
Academic Article Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
Academic Article SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
Academic Article Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus.
Academic Article International network of cancer genome projects.
Academic Article Expression profile analysis of colon cancer cells in response to sulindac or aspirin.
Academic Article Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.
Academic Article Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers.
Academic Article Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.
Academic Article Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN.
Academic Article Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas.
Academic Article FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
Academic Article Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
Academic Article Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
Academic Article Molecular target therapy for synovial sarcoma.
Academic Article Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP Maps, of 199 drug-related genes in 752 subjects: the analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs.
Academic Article Catalog of 77 single-nucleotide polymorphisms (SNPs) in the carbohydrate sulfotransferase 1 (CHST1) and carbohydrate sulfotransferase 3 (CHST3) genes.
Academic Article Isolation of a novel gene, CABC1, encoding a mitochondrial protein that is highly homologous to yeast activity of bc1 complex.
Academic Article Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues.
Academic Article Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
Academic Article Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
Academic Article Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
Academic Article Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection.
Academic Article DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
Academic Article SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article Identification of COX17 as a therapeutic target for non-small cell lung cancer.
Academic Article Regulation of iron homeostasis by the p53-ISCU pathway.
Academic Article SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
Academic Article Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy.
Academic Article Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells.
Academic Article HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.
Academic Article Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.
Academic Article Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
Academic Article Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
Academic Article Isolation of p53-target genes and their functional analysis.
Academic Article Retraction. Cloning and expression of soluble recombinant human esophageal cancer-related gene 4 protein and its inhibitory effect on tumor growth in vitro and in vivo in esophageal carcinoma.
Academic Article Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.
Academic Article From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma.
Academic Article Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation.
Academic Article Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
Academic Article Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma.
Academic Article Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
Academic Article Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Academic Article Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
Academic Article Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.
Academic Article Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
Academic Article Characterization of a VNTR polymorphism in the coding region of the CEL gene.
Academic Article Construction and characterization of a vestibular-specific cDNA library using T7-based RNA amplification.
Academic Article Mutations in the gene encoding KIAA1199 protein, an inner-ear protein expressed in Deiters' cells and the fibrocytes, as the cause of nonsyndromic hearing loss.
Academic Article WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
Academic Article Host cell-specific effects of lentiviral accessory proteins on the eukaryotic cell cycle progression.
Academic Article SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1.
Academic Article WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
Academic Article GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Academic Article Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
Academic Article Predicting response of bladder cancers to gemcitabine and carboplatin neoadjuvant chemotherapy through genome-wide gene expression profiling.
Academic Article Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection.
Academic Article Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer.
Academic Article Identification of a set of genes associated with response to interleukin-2 and interferon-a combination therapy for renal cell carcinoma through genome-wide gene expression profiling.
Academic Article Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.
Academic Article The Transcriptional Landscape of p53 Signalling Pathway.
Academic Article Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
Academic Article Characterization of the T-Cell Receptor Repertoire and Immune Microenvironment in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck.
Academic Article Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia.
Academic Article The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
Academic Article miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
Academic Article Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells.
Academic Article Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
Academic Article Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
Academic Article MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
Academic Article The GALNT6-LGALS3BP axis promotes breast cancer cell growth.
Academic Article Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
Academic Article Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens.
Academic Article Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy.
Academic Article Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?
Academic Article Enhancement of Migration and Invasion of Gastric Cancer Cells by IQGAP3.
Academic Article Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
Academic Article Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension.
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