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Nakamura, Yusuke
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Concept Chromosomes, Human, Pair 11
Concept Chromosomes, Human, Pair 2
Concept Chromosomes, Human, Pair 6
Concept Chromosomes, Human, Pair 8
Concept Chromosomes, Human, Pair 1
Concept Chromosomes, Human, Pair 15
Concept Chromosomes, Human, Pair 21
Concept Chromosomes, Human, Pair 3
Concept Chromosomes, Human, Pair 12
Concept Chromosomes, Human, Pair 14
Concept Chromosomes, Human, Pair 13
Concept Chromosomes, Human, Pair 22
Concept Chromosomes, Human, Pair 4
Concept Chromosomes, Human, Pair 5
Concept Chromosomes, Human, Pair 7
Concept Chromosomes, Human, Pair 20
Concept Chromosomes, Human, Pair 10
Concept Chromosomes, Human, Pair 17
Concept Chromosomes, Human, Pair 19
Concept Chromosomes, Human, Pair 9
Concept Humans
Concept Herpesvirus 1, Human
Concept Human Genome Project
Concept Human T-lymphotropic virus 1
Concept Genome, Human
Concept Human papillomavirus 16
Concept vpr Gene Products, Human Immunodeficiency Virus
Concept Chromosomes, Human
Concept Chromosomes, Human, Pair 16
Concept Chromosomes, Human, Pair 18
Concept Chromosomes, Human, X
Concept Mammary Glands, Human
Academic Article The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
Academic Article Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs.
Academic Article An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines.
Academic Article A physical and genetic linkage map of the distal long arm of human chromosome 5.
Academic Article Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs.
Academic Article Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
Academic Article Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.
Academic Article Ring finger protein 43 as a new target for cancer immunotherapy.
Academic Article Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.
Academic Article Mouse homologue of a novel human oncofetal antigen, glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in mice.
Academic Article Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.
Academic Article Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
Academic Article Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients.
Academic Article A SNP in the ABCC11 gene is the determinant of human earwax type.
Academic Article Multiplex PCR-based real-time invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions.
Academic Article Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
Academic Article Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Academic Article When good drugs go bad.
Academic Article A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.
Academic Article Genome-wide detection and characterization of positive selection in human populations.
Academic Article Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
Academic Article Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
Academic Article Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia.
Academic Article Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function.
Academic Article Predicting response to docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling.
Academic Article Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
Academic Article Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.
Academic Article Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies.
Academic Article A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
Academic Article A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma.
Academic Article HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients.
Academic Article Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
Academic Article Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
Academic Article Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
Academic Article Criterion values for multiplex SNP genotyping by the invader assay.
Academic Article Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression.
Academic Article Automated SNPs typing system based on the Invader assay.
Academic Article Making a haplotype catalog with estimated frequencies based on SNP homozygotes.
Academic Article Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.
Academic Article Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
Academic Article Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma.
Academic Article Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
Academic Article Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
Academic Article The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
Academic Article HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis.
Academic Article Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
Academic Article Genome-wide association study of intracranial aneurysm identifies three new risk loci.
Academic Article Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand.
Academic Article Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
Academic Article Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.
Academic Article Phase I clinical trial using peptide vaccine for human vascular endothelial growth factor receptor 2 in combination with gemcitabine for patients with advanced pancreatic cancer.
Academic Article Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
Academic Article Successful outcomes using combination therapy of interleukin-2 and interferon-alpha for renal cell carcinoma patients with lung metastasis.
Academic Article PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
Academic Article Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
Academic Article Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.
Academic Article A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
Academic Article Establishment of a standardized system to perform population structure analyses with limited sample size or with different sets of SNP genotypes.
Academic Article Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
Academic Article Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
Academic Article A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
Academic Article Impact of LIMK1, MMP2 and TNF-a variations for intracranial aneurysm in Japanese population.
Academic Article Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
Academic Article Common variation in GPC5 is associated with acquired nephrotic syndrome.
Academic Article Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
Academic Article Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy.
Academic Article Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
Academic Article A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
Academic Article SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
Academic Article Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.
Academic Article Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
Academic Article Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.
Academic Article ADAM8 as a novel serological and histochemical marker for lung cancer.
Academic Article Should CYP2D6 inhibitors be administered in conjunction with tamoxifen?
Academic Article Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
Academic Article Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese.
Academic Article A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
Academic Article New pharmacogenetic test for detecting an HLA-A*31: 01 allele using the InvaderPlus assay.
Academic Article Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis.
Academic Article Genome-wide association study of epirubicin-induced leukopenia in Japanese patients.
Academic Article Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials.
Academic Article Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese.
Academic Article Genome-wide association meta-analysis identifies new endometriosis risk loci.
Academic Article Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
Academic Article A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
Academic Article Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial.
Academic Article Evaluating genetic risk for prostate cancer among Japanese and Latinos.
Academic Article Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
Academic Article A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
Academic Article A genome-wide association study identifies three new risk loci for Kawasaki disease.
Academic Article Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
Academic Article SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
Academic Article Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
Academic Article Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
Academic Article Multiple loci are associated with white blood cell phenotypes.
Academic Article Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
Academic Article Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.
Academic Article New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article Physical localization of 70 polymorphic markers to human chromosome 5 by fluorescence in situ hybridization.
Academic Article Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor administration.
Academic Article A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
Academic Article Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response.
Academic Article A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
Academic Article A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression.
Academic Article Meta-analysis identifies common variants associated with body mass index in east Asians.
Academic Article A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis.
Academic Article A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
Academic Article Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing.
Academic Article A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
Academic Article Optineurin mutations in Japanese amyotrophic lateral sclerosis.
Academic Article Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.
Academic Article Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
Academic Article Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients.
Academic Article Pharmacogenomics of tamoxifen: roles of drug metabolizing enzymes and transporters.
Academic Article Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.
Academic Article PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
Academic Article A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
Academic Article A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.
Academic Article Prostate cancer genomics, biology, and risk assessment through genome-wide association studies.
Academic Article A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
Academic Article A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
Academic Article Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Academic Article Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.
Academic Article Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes.
Academic Article Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.
Academic Article A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
Academic Article Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
Academic Article Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
Academic Article Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.
Academic Article Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.
Academic Article Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
Academic Article Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer.
Academic Article CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans.
Academic Article Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.
Academic Article IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.
Academic Article Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese.
Academic Article Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
Academic Article A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.
Academic Article Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
Academic Article Pharmacogenomics and patient care: one size does not fit all.
Academic Article Functional variants in NFKBIE and RTKN2 involved in activation of the NF-?B pathway are associated with rheumatoid arthritis in Japanese.
Academic Article Physical and genetic map of 5q31: use of fluorescence in situ hybridization data to identify errors in the CEPH database. Centre d'Etude de Polymorphisme Humain.
Academic Article High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population.
Academic Article A second generation human haplotype map of over 3.1 million SNPs.
Academic Article Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer.
Academic Article Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
Academic Article Activation of placenta-specific transcription factor distal-less homeobox 5 predicts clinical outcome in primary lung cancer patients.
Academic Article SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis.
Academic Article Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.
Academic Article CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection.
Academic Article Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.
Academic Article Genome-wide association study of hematological and biochemical traits in a Japanese population.
Academic Article A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
Academic Article A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.
Academic Article Replication study for the association between four Loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes.
Academic Article Genome-wide association study of pancreatic cancer in Japanese population.
Academic Article IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
Academic Article Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level.
Academic Article Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).
Academic Article Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.
Academic Article Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
Academic Article Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.
Academic Article ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations.
Academic Article Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma.
Academic Article Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis.
Academic Article Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
Academic Article Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy.
Academic Article Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population.
Academic Article Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
Academic Article Lack of association between variations of PDE4D and ischemic stroke in the Japanese population.
Academic Article A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.
Academic Article Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1.
Academic Article Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
Academic Article Polymorphic human insulin-responsive glucose-transporter gene on chromosome 17p13.
Academic Article Development of new HLA-B*3505 genotyping method using Invader assay.
Academic Article Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
Academic Article IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.
Academic Article Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.
Academic Article A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
Academic Article HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
Academic Article A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
Academic Article Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer.
Academic Article Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Academic Article Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
Academic Article A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.
Academic Article A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
Academic Article Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
Academic Article Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.
Academic Article Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
Academic Article Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy.
Academic Article Nucleotide pyrophosphatase gene polymorphism associated with ossification of the posterior longitudinal ligament of the spine.
Academic Article Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray.
Academic Article Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
Academic Article Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
Academic Article Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21.
Academic Article Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.
Academic Article Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
Academic Article Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors.
Academic Article Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations.
Academic Article Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: identification of genes associated with progression and metastasis.
Academic Article Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas.
Academic Article Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
Academic Article Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais.
Academic Article Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction.
Academic Article [A phase I study of combination-therapy with gemcitabine and epitope peptides derived from human vascular endothelial growth factor receptor for unresectable or recurrent pancreas cancer].
Academic Article Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray.
Academic Article Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
Academic Article Critical roles of mucin 1 glycosylation by transactivated polypeptide N-acetylgalactosaminyltransferase 6 in mammary carcinogenesis.
Academic Article Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
Academic Article Involvement of C12orf32 overexpression in breast carcinogenesis.
Academic Article Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray.
Academic Article Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
Academic Article Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.
Academic Article Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes.
Academic Article Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene.
Academic Article Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
Academic Article Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.
Academic Article Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53.
Academic Article Functional haplotypes of IL-12B are associated with childhood atopic asthma.
Academic Article A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
Academic Article Identification of 156 novel SNPs in 29 genes encoding G-protein coupled receptors.
Academic Article Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
Academic Article Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
Academic Article Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles.
Academic Article Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer.
Academic Article Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
Academic Article Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
Academic Article Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis.
Academic Article A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
Academic Article Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro.
Academic Article Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
Academic Article Serum REG4 level is a predictive biomarker for the response to preoperative chemoradiotherapy in patients with pancreatic cancer.
Academic Article Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.
Academic Article Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
Academic Article Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
Academic Article Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Academic Article An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
Academic Article Common variants in CASP3 confer susceptibility to Kawasaki disease.
Academic Article The textile plot: a new linkage disequilibrium display of multiple-single nucleotide polymorphism genotype data.
Academic Article Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
Academic Article EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth.
Academic Article Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs.
Academic Article Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
Academic Article Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
Academic Article Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
Academic Article Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
Academic Article Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring.
Academic Article Impact of four loci on serum tamsulosin hydrochloride concentration.
Academic Article High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
Academic Article Variations in the FTO gene are associated with severe obesity in the Japanese.
Academic Article C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
Academic Article PKIB expression strongly correlated with phosphorylated Akt expression in breast cancers and also with triple-negative breast cancer subtype.
Academic Article Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.
Academic Article A comprehensive peptidome profiling technology for the identification of early detection biomarkers for lung adenocarcinoma.
Academic Article INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
Academic Article Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
Academic Article Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
Academic Article Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.
Academic Article Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
Academic Article Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer.
Academic Article A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
Academic Article Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Academic Article Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
Academic Article Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Academic Article MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
Academic Article Impact of PSCA variation on gastric ulcer susceptibility.
Academic Article Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
Academic Article A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
Academic Article Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
Academic Article Genome-wide gene expression profiles of clear cell renal cell carcinoma: identification of molecular targets for treatment of renal cell carcinoma.
Academic Article A genomewide linkage analysis of Kawasaki disease: evidence for linkage to chromosome 12.
Academic Article Genome wide association study of age at menarche in the Japanese population.
Academic Article Association of the RIP2 gene with childhood atopic asthma.
Academic Article Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
Academic Article CYP2D6 genotype and tamoxifen activity: understanding interstudy variability in methodological quality.
Academic Article Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer.
Academic Article ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.
Academic Article MOCSphaser: a haplotype inference tool from a mixture of copy number variation and single nucleotide polymorphism data.
Academic Article Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
Academic Article Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays.
Academic Article Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
Academic Article Overexpression of the potential kinase serine/ threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer.
Academic Article Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
Academic Article Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.
Academic Article Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.
Academic Article Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
Academic Article ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.
Academic Article HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy.
Academic Article Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin.
Academic Article A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
Academic Article TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
Academic Article Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia.
Academic Article Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.
Academic Article Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese.
Academic Article Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
Academic Article Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk.
Academic Article Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies.
Academic Article High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
Academic Article Identification of CAG repeat-containing genes expressed in human brain as candidate genes for autosomal dominant spinocerebellar ataxias and other neurodegenerative diseases.
Academic Article Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.
Academic Article Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice.
Academic Article Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.
Academic Article Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
Academic Article A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis.
Academic Article Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
Academic Article Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
Academic Article Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population.
Academic Article Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
Academic Article 5alphaDH-DOC (5alpha-dihydro-deoxycorticosterone) activates androgen receptor in castration-resistant prostate cancer.
Academic Article Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
Academic Article The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
Academic Article Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.
Academic Article Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
Academic Article Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis.
Academic Article Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
Academic Article Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Academic Article Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).
Academic Article An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
Academic Article Seven new loci associated with age-related macular degeneration.
Academic Article Pathway analysis of genome-wide data improves warfarin dose prediction.
Academic Article Cyclin K as a direct transcriptional target of the p53 tumor suppressor.
Academic Article Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Academic Article Trans-ethnic meta-analysis of white blood cell phenotypes.
Academic Article Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.
Academic Article Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
Academic Article Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
Academic Article Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
Academic Article An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis.
Academic Article Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.
Academic Article p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
Academic Article A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population.
Academic Article Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
Academic Article SMYD3 interacts with HTLV-1 Tax and regulates subcellular localization of Tax.
Academic Article High-resolution SNP map in the 55-kb region containing the selectin gene family on chromosome 1q24-q25.
Academic Article Crosstalk of EDA-A2/XEDAR in the p53 signaling pathway.
Academic Article Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells.
Academic Article Guidance for peptide vaccines for the treatment of cancer.
Academic Article Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy.
Academic Article New gene functions in megakaryopoiesis and platelet formation.
Academic Article Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
Academic Article Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
Academic Article The Xq22 inversion breakpoint interrupted a novel Ras-like GTPase gene in a patient with Duchenne muscular dystrophy and profound mental retardation.
Academic Article Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population.
Academic Article Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell.
Academic Article Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Academic Article Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8.
Academic Article Maturational sequence of neuroblastoma revealed by molecular analysis on cDNA microarrays.
Academic Article Comparison of gene expression profiles between Opisthorchis viverrini and non-Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma.
Academic Article CD40 ligand gene and Kawasaki disease.
Academic Article DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway.
Academic Article Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma.
Academic Article Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth.
Academic Article Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
Academic Article Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
Academic Article p53AIP1 regulates the mitochondrial apoptotic pathway.
Academic Article Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
Academic Article Catalog of 238 variations among six human genes encoding solute carriers ( hSLCs) in the Japanese population.
Academic Article Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.
Academic Article Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease.
Academic Article Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis.
Academic Article Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
Academic Article The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
Academic Article The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer.
Academic Article ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
Academic Article Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
Academic Article Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.
Academic Article Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer.
Academic Article Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
Academic Article DNA variations in human and medical genetics: 25 years of my experience.
Academic Article Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.
Academic Article Predictive biomarkers for the outcome of vaccination of five therapeutic epitope peptides for colorectal cancer.
Academic Article Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
Academic Article Twenty single-nucleotide polymorphisms in four genes encoding cardiac ion channels.
Academic Article 906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.
Academic Article Linkage disequilibrium of evolutionarily conserved regions in the human genome.
Academic Article Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma.
Academic Article A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
Academic Article Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).
Academic Article Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers.
Academic Article [Therapeutic cancer vaccines against gastro-intestinal cancer].
Academic Article A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction.
Academic Article Non-transmissible Sendai virus encoding granulocyte macrophage colony-stimulating factor is a novel and potent vector system for producing autologous tumor vaccines.
Academic Article Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
Academic Article Oncogenic role of NALP7 in testicular seminomas.
Academic Article Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.
Academic Article Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
Academic Article In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy.
Academic Article [SNP collection, pharmacogenomics, and the future of drug therapy].
Academic Article Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
Academic Article WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
Academic Article Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.
Academic Article p53RDL1 regulates p53-dependent apoptosis.
Academic Article Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy.
Academic Article RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Host molecular defense mechanisms against Chlamydophila pneumoniae and genetic studies of immune-response-related genes in asthma.
Academic Article Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.
Academic Article Colorectal cancer metastasis to the thyroid.
Academic Article Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.
Academic Article A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
Academic Article Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
Academic Article Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
Academic Article Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population.
Academic Article Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor.
Academic Article Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
Academic Article Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition.
Academic Article [Possible role of genetic factors on reduced risk for gastric cancer among duodenal ulcer patients].
Academic Article Expression profiles of two types of human knee-joint cartilage.
Academic Article Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
Academic Article High-density SNP map of human ITR, a gene associated with vascular remodeling.
Academic Article Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
Academic Article Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
Academic Article Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer.
Academic Article Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.
Academic Article Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
Academic Article A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.
Academic Article Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.
Academic Article Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas.
Academic Article Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
Academic Article SNPs in BRAP associated with risk of myocardial infarction in Asian populations.
Academic Article Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.
Academic Article Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.
Academic Article Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism.
Academic Article Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma.
Academic Article Genetic polymorphisms in the IL22 gene are associated with psoriasis vulgaris in a Japanese population.
Academic Article Cancer vaccines.
Academic Article [Phase I study of combination therapy with peptide vaccine and anti-cancer drug for colorectal cancer].
Academic Article Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface.
Academic Article Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
Academic Article Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
Academic Article Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma.
Academic Article CLCA2 as a p53-inducible senescence mediator.
Academic Article Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
Academic Article Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
Academic Article PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
Academic Article Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
Academic Article Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers.
Academic Article Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
Academic Article Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Academic Article Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes.
Academic Article Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
Academic Article A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
Academic Article Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.
Academic Article Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs).
Academic Article Analysis of gene-expression profiles after gamma irradiation of normal human fibroblasts.
Academic Article Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.
Academic Article A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
Academic Article Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
Academic Article A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
Academic Article Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
Academic Article Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis.
Academic Article Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
Academic Article A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
Academic Article Hypoxia-inducible protein 2 (HIG2), a novel diagnostic marker for renal cell carcinoma and potential target for molecular therapy.
Academic Article Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Academic Article Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
Academic Article Plakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancer.
Academic Article WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
Academic Article Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.
Academic Article Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
Academic Article hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
Academic Article Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.
Academic Article A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
Academic Article Plasma low-molecular-weight proteome profiling identified neuropeptide-Y as a prostate cancer biomarker polypeptide.
Academic Article Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.
Academic Article ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence.
Academic Article The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
Academic Article EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.
Academic Article Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
Academic Article Institutional Profile: University of Chicago Center for Personalized Therapeutics: research, education and implementation science.
Academic Article A functional polymorphism in IL-18 is associated with severity of bronchial asthma.
Academic Article Tumor budding is a significant indicator of a poor prognosis in lung squamous cell carcinoma patients.
Academic Article Prediction of response to imatinib by cDNA microarray analysis.
Academic Article Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas.
Academic Article A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.
Academic Article Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma.
Academic Article Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
Academic Article A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Academic Article Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
Academic Article Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
Academic Article RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation.
Academic Article Genome-wide association study of breast cancer in the Japanese population.
Academic Article Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
Academic Article Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
Academic Article Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
Academic Article Prevalence of allergic rhinitis and sensitization to common aeroallergens in a Japanese population.
Academic Article Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Academic Article No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.
Academic Article The BioBank Japan Project.
Academic Article High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.
Academic Article [S-1/CDDP combined neoadjuvant chemotherapy and surgical resection for advanced gastric cancer. Analysis of 12 patients with lymph node metastasis in Saitama Red Cross Hospital].
Academic Article Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
Academic Article Recombination rates of genes expressed in human tissues.
Academic Article Japanese single nucleotide polymorphism database for 267 possible drug-related genes.
Academic Article The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.
Academic Article hzAnalyzer: detection, quantification, and visualization of contiguous homozygosity in high-density genotyping datasets.
Academic Article Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
Academic Article Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
Academic Article Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10.
Academic Article Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer.
Academic Article Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
Academic Article MRG-binding protein contributes to colorectal cancer development.
Academic Article IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C.
Academic Article Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit.
Academic Article Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
Academic Article Enhanced SMYD3 expression is essential for the growth of breast cancer cells.
Academic Article Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
Academic Article Identification of an HLA-A2-restricted epitope peptide derived from hypoxia-inducible protein 2 (HIG2).
Academic Article Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
Academic Article Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.
Academic Article HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
Academic Article [BioBank Japan project].
Academic Article The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort.
Academic Article Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus.
Academic Article Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
Academic Article Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
Academic Article Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
Academic Article ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
Academic Article A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
Academic Article Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
Academic Article Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
Academic Article Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
Academic Article Expression profiles of metastatic brain tumor from lung adenocarcinomas on cDNA microarray.
Academic Article Critical roles of T-LAK cell-originated protein kinase in cytokinesis.
Academic Article The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Academic Article Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
Academic Article Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
Academic Article Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.
Academic Article Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese.
Academic Article A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.
Academic Article A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
Academic Article The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Academic Article Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
Academic Article Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.
Academic Article The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells.
Academic Article Detection of novel cancer-testis antigen-specific T-cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carcinoma.
Academic Article A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
Academic Article Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1.
Academic Article A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability.
Academic Article A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
Academic Article Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Academic Article Population-genetic nature of copy number variations in the human genome.
Academic Article Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
Academic Article Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.
Academic Article Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.
Academic Article A functional polymorphism in MMP-9 is associated with childhood atopic asthma.
Academic Article A single nucleotide polymorphism in KCNQ1 is associated with susceptibility to diabetic nephropathy in japanese subjects with type 2 diabetes.
Academic Article Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
Academic Article The p53 family member genes are involved in the Notch signal pathway.
Academic Article A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
Academic Article Identification of semaphorin3B as a direct target of p53.
Academic Article Prediction of outcome of advanced cervical cancer to thermoradiotherapy according to expression profiles of 35 genes selected by cDNA microarray analysis.
Academic Article Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
Academic Article Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
Academic Article Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix.
Academic Article Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
Academic Article A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.
Academic Article The DNA binding site specificity and antiproliferative property of ternary Pt(II) and Zn(II) complexes of phenanthroline and N,N'-ethylenediaminediacetic acid.
Academic Article Variation of gene-based SNPs and linkage disequilibrium patterns in the human genome.
Academic Article Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas.
Academic Article Functional impact of IgA nephropathy-associated selectin gene haplotype on leukocyte-endothelial interaction.
Academic Article Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.
Academic Article Gene expression profiles of small-cell lung cancers: molecular signatures of lung cancer.
Academic Article SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.
Academic Article The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
Academic Article An algorithm for inferring complex haplotypes in a region of copy-number variation.
Academic Article Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
Academic Article Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
Academic Article New correction algorithms for multiple comparisons in case-control multilocus association studies based on haplotypes and diplotype configurations.
Academic Article Heterozygous TGFBR2 mutations in Marfan syndrome.
Academic Article SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
Academic Article Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus.
Academic Article International network of cancer genome projects.
Academic Article Reevaluation of a lectin antibody ELISA kit for measuring fucosylated haptoglobin in various conditions.
Academic Article Expression profile analysis of colon cancer cells in response to sulindac or aspirin.
Academic Article Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.
Academic Article Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers.
Academic Article Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis.
Academic Article Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.
Academic Article Critical roles of non-histone protein lysine methylation in human tumorigenesis.
Academic Article A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers.
Academic Article Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.
Academic Article Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN.
Academic Article Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas.
Academic Article An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway.
Academic Article FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
Academic Article Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
Academic Article Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
Academic Article Molecular target therapy for synovial sarcoma.
Academic Article Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP Maps, of 199 drug-related genes in 752 subjects: the analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs.
Academic Article Catalog of 77 single-nucleotide polymorphisms (SNPs) in the carbohydrate sulfotransferase 1 (CHST1) and carbohydrate sulfotransferase 3 (CHST3) genes.
Academic Article A phase ?I study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study).
Academic Article Isolation of a novel gene, CABC1, encoding a mitochondrial protein that is highly homologous to yeast activity of bc1 complex.
Academic Article PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer.
Academic Article TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
Academic Article Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues.
Academic Article Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
Academic Article Oncogenic role of MPHOSPH1, a cancer-testis antigen specific to human bladder cancer.
Academic Article Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
Academic Article Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
Academic Article Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
Academic Article Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
Academic Article DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
Academic Article Re: Concordance between CYP2D6 genotypes obtained from tumor-derived and germline DNA.
Academic Article SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
Academic Article Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients.
Academic Article Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.
Academic Article The NSD family of protein methyltransferases in human cancer.
Academic Article PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article Identification of COX17 as a therapeutic target for non-small cell lung cancer.
Academic Article Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
Academic Article Regulation of iron homeostasis by the p53-ISCU pathway.
Academic Article PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP.
Academic Article SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
Academic Article Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases.
Academic Article Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy.
Academic Article Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells.
Academic Article HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.
Academic Article Identification of CDCA1-derived long peptides bearing both CD4+ and CD8+ T-cell epitopes: CDCA1-specific CD4+ T-cell immunity in cancer patients.
Academic Article Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.
Academic Article Understanding the functional significance of ghrelin processing and degradation.
Academic Article Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
Academic Article Germline PARP4 mutations in patients with primary thyroid and breast cancers.
Academic Article Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
Academic Article Importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies.
Academic Article Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
Academic Article Isolation of p53-target genes and their functional analysis.
Academic Article Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
Academic Article Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on radiosensitivity.
Academic Article Retraction. Cloning and expression of soluble recombinant human esophageal cancer-related gene 4 protein and its inhibitory effect on tumor growth in vitro and in vivo in esophageal carcinoma.
Academic Article Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
Academic Article Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.
Academic Article Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.
Academic Article Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: evaluation in comparison with mesothelin.
Academic Article Herpes simplex virus-induced, death receptor-dependent apoptosis and regression of transplanted human cancers.
Academic Article Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer.
Academic Article Identification of HLA-A24-restricted novel T Cell epitope peptides derived from P-cadherin and kinesin family member 20A.
Academic Article Lobectomy of pulmonary metastasis of endometrial stromal sarcoma.
Academic Article From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma.
Academic Article Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation.
Academic Article Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
Academic Article Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapy.
Academic Article The current and future applications of immunopharmacogenomics.
Academic Article Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.
Academic Article Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma.
Academic Article Recurrence in regional pulmonary lymph nodes after surgery for isolated pulmonary metastasis from hepatocellular carcinoma.
Academic Article Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
Academic Article Lobectomy of second primary cancer in survivor of small cell lung cancer with brain metastasis.
Academic Article Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown.
Academic Article Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations.
Academic Article Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors.
Academic Article Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy.
Academic Article Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Academic Article Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Deep-sequencing of the T-cell receptor repertoire in patients with haplo-cord and matched-donor transplants.
Academic Article Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
Academic Article Myasthenic crisis and polymyositis induced by one dose of nivolumab.
Academic Article Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins.
Academic Article Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
Academic Article Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
Academic Article Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells.
Academic Article Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.
Academic Article [A case with an ovarian cancer patient who could receive anti-cancer therapy and palliative care simultaneously at home through seamless collaboration in healthcare linkage].
Academic Article Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
Academic Article p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.
Academic Article The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
Academic Article Pharmacogenomics and drug toxicity.
Academic Article Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells.
Academic Article Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma.
Academic Article Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
Academic Article Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study.
Academic Article Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study.
Academic Article Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy.
Academic Article Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL).
Academic Article T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
Academic Article Characterization of a VNTR polymorphism in the coding region of the CEL gene.
Academic Article Construction and characterization of a vestibular-specific cDNA library using T7-based RNA amplification.
Academic Article Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors.
Academic Article Mutations in the gene encoding KIAA1199 protein, an inner-ear protein expressed in Deiters' cells and the fibrocytes, as the cause of nonsyndromic hearing loss.
Academic Article HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.
Academic Article WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
Academic Article Host cell-specific effects of lentiviral accessory proteins on the eukaryotic cell cycle progression.
Academic Article SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1.
Academic Article TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
Academic Article WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
Academic Article GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Academic Article Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project.
Academic Article Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
Academic Article Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan.
Academic Article Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection.
Academic Article Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases.
Academic Article Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan.
Academic Article Overview of BioBank Japan follow-up data in 32 diseases.
Academic Article Statin use and all-cause and cancer mortality: BioBank Japan cohort.
Academic Article Overview of the BioBank Japan Project: Study design and profile.
Academic Article Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project.
Academic Article Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer.
Academic Article Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project.
Academic Article Characteristics of patients with liver cancer in the BioBank Japan project.
Academic Article Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project.
Academic Article Tracheal Bronchus: Beware of Anomalous Venous Drainage!
Academic Article Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project.
Academic Article Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
Academic Article Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
Academic Article Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort.
Academic Article Clinical and histopathological characteristics of patients with prostate cancer in the BioBank Japan project.
Academic Article Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.
Academic Article Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.
Academic Article Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
Academic Article SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
Academic Article Case of malignant melanoma that developed the ability to secrete granulocyte colony-stimulating factor.
Academic Article Phase I clinical trial of cell division associated 1 (CDCA1) peptide vaccination for castration resistant prostate cancer.
Academic Article Toxic epidermal necrolysis in a child 6 months post-hematopoietic stem cell transplantation.
Academic Article The Transcriptional Landscape of p53 Signalling Pathway.
Academic Article Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
Academic Article Characterization of the T-Cell Receptor Repertoire and Immune Microenvironment in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck.
Academic Article [A case of inoperable gastric small cell carcinoma effectively treated by chemotherapy and radiotherapy].
Academic Article Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients.
Academic Article Third-generation oncolytic herpes simplex virus inhibits the growth of liver tumors in mice.
Academic Article Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia.
Academic Article Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor-Engineered T Cells for Ovarian Cancer.
Academic Article The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
Academic Article miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
Academic Article A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
Academic Article Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.
Academic Article Phase I Study of Multiple Epitope Peptide Vaccination in Patients With Recurrent or Persistent Cervical Cancer.
Academic Article Critical roles of protein methyltransferases and demethylases in the regulation of embryonic stem cell fate.
Academic Article GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
Academic Article Immunoglobulin profiling identifies unique signatures in patients with Kawasaki disease during intravenous immunoglobulin treatment.
Academic Article The era of immunogenomics/immunopharmacogenomics.
Academic Article The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck.
Academic Article Video-assisted segmental resection of an intrapulmonary bronchogenic cyst mimicking a middle mediastinal cystic tumor.
Academic Article Free-floating cancer cells in lymph node sinuses of hilar lymph node-positive patients with non-small cell lung cancer.
Academic Article Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens.
Academic Article Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
Academic Article Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy.
Academic Article A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients.
Academic Article Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.
Academic Article a-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 10.
Academic Article Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells.
Academic Article Diagnostic utility and pitfalls of intraoperative pulmonary imprint cytology based on final pathological diagnoses.
Academic Article Breast cancer: The translation of big genomic data to cancer precision medicine.
Academic Article Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
Academic Article Significant differences in T cell receptor repertoires in lung adenocarcinomas with and without epidermal growth factor receptor mutations.
Academic Article Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
Academic Article MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
Academic Article A biosafety algorithm for the protection of pathology staff during intraoperative examinations of pulmonary lesions.
Academic Article The road map of cancer precision medicine with the innovation of advanced cancer detection technology and personalized immunotherapy.
Academic Article Tamoxifen Metabolism and Breast Cancer Recurrence: A Question Unanswered by CYPTAM.
Academic Article Immune profiles in primary squamous cell carcinoma of the head and neck.
Academic Article Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
Academic Article Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population.
Academic Article The GALNT6-LGALS3BP axis promotes breast cancer cell growth.
Academic Article Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progression-free survival.
Academic Article Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
Academic Article Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.
Academic Article Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens.
Academic Article Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2.
Academic Article Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy.
Academic Article WHSC1 monomethylates histone H1 and induces stem-cell like features in squamous cell carcinoma of the head and neck.
Academic Article Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.
Academic Article Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?
Academic Article Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites.
Academic Article SARS-CoV-2 genomic variations associated with mortality rate of COVID-19.
Academic Article CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
Academic Article Enhancement of Migration and Invasion of Gastric Cancer Cells by IQGAP3.
Academic Article Clinicopathologic significance of protein lysine methyltransferases in cancer.
Academic Article Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects.
Academic Article High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo.
Academic Article Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer.
Academic Article Anti-cancer immunotherapy using cancer-derived multiple epitope-peptides cocktail vaccination clinical studies in patients with refractory/persistent disease of uterine cervical cancer and ovarian cancer [phase 2].
Academic Article Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
Academic Article Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome.
Academic Article Diversity in immunogenomics: the value and the challenge.
Academic Article Clinical implementation and current advancement of blood liquid biopsy in cancer.
Academic Article Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma.
Academic Article Neoantigens elicit T cell responses in breast cancer.
Academic Article Immunogenomics in personalized cancer treatments.
Academic Article Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis.
Academic Article Functional genomics for breast cancer drug target discovery.
Academic Article Contribution of pre-existing neoantigen-specific T cells to a durable complete response after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma.
Academic Article Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer.
Academic Article A cross-population atlas of genetic associations for 220 human phenotypes.
Academic Article FZD10-targeted a-radioimmunotherapy with 225 Ac-labeled OTSA101 achieves complete remission in a synovial sarcoma model.
Academic Article Identification of cytotoxic T cells and their T cell receptor sequences targeting COVID-19 using MHC class I-binding peptides.
Academic Article Serial circulating tumor DNA monitoring of CDK4/6 inhibitors response in metastatic breast cancer.
Academic Article Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension.
Academic Article Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy.
Academic Article Tumor-Informed Approach Improved ctDNA Detection Rate in Resected Pancreatic Cancer.
Academic Article Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials.
Academic Article SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
Academic Article Immunological analysis of hybrid neoantigen peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.
Academic Article One CD4+TCR and One CD8+TCR Targeting Autochthonous Neoantigens Are Essential and Sufficient for Tumor Eradication.
Academic Article Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance).
Academic Article Identification of RNF213 as a Potential Suppressor of Local Invasion in Intrahepatic Cholangiocarcinoma.
Academic Article Characterization of double-negative T cells in colorectal cancers and their corresponding lymph nodes.
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