Item Type | Name |
Concept
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Age Factors
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Concept
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Immunologic Factors
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Concept
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Fibroblast Growth Factors
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Concept
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Nerve Growth Factors
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Concept
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Plasmids
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Concept
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Transcription Factors
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Concept
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Risk Factors
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Concept
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Time Factors
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Concept
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Guanine Nucleotide Exchange Factors
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Concept
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E2F Transcription Factors
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Concept
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ras Guanine Nucleotide Exchange Factors
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Concept
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TATA-Binding Protein Associated Factors
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Concept
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Transcriptional Elongation Factors
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Concept
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GATA Transcription Factors
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Concept
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Interferon Regulatory Factors
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Concept
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SOXB1 Transcription Factors
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Concept
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Kruppel-Like Transcription Factors
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Concept
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Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
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Concept
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TCF Transcription Factors
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Concept
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Sex Factors
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Concept
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NFATC Transcription Factors
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Concept
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Basic Helix-Loop-Helix Transcription Factors
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Concept
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Forkhead Transcription Factors
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Academic Article
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The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
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Academic Article
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Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
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Academic Article
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Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
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Academic Article
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Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
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Academic Article
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A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
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Academic Article
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Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
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Academic Article
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Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma.
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Academic Article
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Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
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Academic Article
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The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
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Academic Article
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Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.
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Academic Article
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Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
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Academic Article
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PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
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Academic Article
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Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
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Academic Article
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A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
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Academic Article
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Impact of LIMK1, MMP2 and TNF-a variations for intracranial aneurysm in Japanese population.
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Academic Article
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Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
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Academic Article
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Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis.
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Academic Article
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Genome-wide association study of epirubicin-induced leukopenia in Japanese patients.
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Academic Article
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Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese.
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Academic Article
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Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
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Academic Article
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Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
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Academic Article
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Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
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Academic Article
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A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
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Academic Article
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A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression.
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Academic Article
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A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
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Academic Article
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Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.
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Academic Article
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A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
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Academic Article
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A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
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Academic Article
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Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
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Academic Article
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A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
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Academic Article
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Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
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Academic Article
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Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese.
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Academic Article
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Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
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Academic Article
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Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
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Academic Article
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Activation of placenta-specific transcription factor distal-less homeobox 5 predicts clinical outcome in primary lung cancer patients.
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Academic Article
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Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.
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Academic Article
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Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level.
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Academic Article
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Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
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Academic Article
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Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.
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Academic Article
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HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
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Academic Article
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A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
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Academic Article
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A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.
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Academic Article
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A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
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Academic Article
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Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy.
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Academic Article
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Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
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Academic Article
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Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction.
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Academic Article
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Functional haplotypes of IL-12B are associated with childhood atopic asthma.
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Academic Article
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A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
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Academic Article
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Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
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Academic Article
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Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
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Academic Article
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Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro.
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Academic Article
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An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
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Academic Article
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Common variants in CASP3 confer susceptibility to Kawasaki disease.
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Academic Article
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Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
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Academic Article
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Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
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Academic Article
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A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
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Academic Article
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Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
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Academic Article
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Genome wide association study of age at menarche in the Japanese population.
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Academic Article
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A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
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Academic Article
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Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
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Academic Article
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The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
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Academic Article
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Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.
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Academic Article
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Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
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Academic Article
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An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
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Academic Article
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Seven new loci associated with age-related macular degeneration.
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Academic Article
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Cyclin K as a direct transcriptional target of the p53 tumor suppressor.
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Academic Article
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Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.
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Academic Article
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Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.
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Academic Article
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Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells.
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Academic Article
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Maturational sequence of neuroblastoma revealed by molecular analysis on cDNA microarrays.
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Academic Article
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DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway.
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Academic Article
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Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
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Academic Article
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Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
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Academic Article
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Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
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Academic Article
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Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.
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Academic Article
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The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
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Academic Article
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ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
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Academic Article
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Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
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Academic Article
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Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers.
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Academic Article
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p53RDL1 regulates p53-dependent apoptosis.
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Academic Article
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RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.
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Academic Article
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Colorectal cancer metastasis to the thyroid.
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Academic Article
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Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
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Academic Article
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[Possible role of genetic factors on reduced risk for gastric cancer among duodenal ulcer patients].
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Academic Article
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Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
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Academic Article
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Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
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Academic Article
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Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer.
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Academic Article
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Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.
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Academic Article
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SNPs in BRAP associated with risk of myocardial infarction in Asian populations.
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Academic Article
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Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.
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Academic Article
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Cancer vaccines.
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Academic Article
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PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
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Academic Article
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Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
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Academic Article
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A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
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Academic Article
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Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
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Academic Article
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Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
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Academic Article
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WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
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Academic Article
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ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence.
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Academic Article
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The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
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Academic Article
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Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
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Academic Article
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Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
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Academic Article
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Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
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Academic Article
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Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
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Academic Article
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A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
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Academic Article
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Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
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Academic Article
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Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
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Academic Article
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A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
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Academic Article
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Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
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Academic Article
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Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
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Academic Article
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The p53 family member genes are involved in the Notch signal pathway.
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Academic Article
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A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.
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Academic Article
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Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
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Academic Article
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A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers.
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Academic Article
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Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
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Academic Article
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Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
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Academic Article
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Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
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Academic Article
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Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.
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Academic Article
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The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
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Academic Article
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Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study.
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Academic Article
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Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection.
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Academic Article
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Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project.
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Academic Article
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Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project.
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Academic Article
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Characteristics of patients with liver cancer in the BioBank Japan project.
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Academic Article
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Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project.
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Academic Article
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Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project.
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Academic Article
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Clinical and histopathological characteristics of patients with prostate cancer in the BioBank Japan project.
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Academic Article
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GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
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Academic Article
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Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
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Academic Article
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Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.
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Academic Article
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MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
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Academic Article
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Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.
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Academic Article
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SARS-CoV-2 genomic variations associated with mortality rate of COVID-19.
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Concept
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RNA Splicing Factors
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Concept
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Regulatory Factor X Transcription Factors
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Concept
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Rho Guanine Nucleotide Exchange Factors
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Academic Article
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Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance).
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