Item Type | Name |
Concept
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RNA, Neoplasm
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Concept
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RNA, Viral
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Concept
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RNA Splicing
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Concept
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RNA
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Concept
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RNA Polymerase II
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Concept
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Carbon-Carbon Ligases
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Concept
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RNA Splice Sites
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Concept
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RNA Interference
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Concept
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RNA-Binding Protein EWS
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Concept
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RNA-Binding Proteins
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Concept
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RNA Helicases
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Concept
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RNA, Double-Stranded
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Concept
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RNA, Messenger
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Concept
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Ubiquitin-Protein Ligases
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Concept
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RNA, Antisense
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Concept
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ATP-Binding Cassette Transporters
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Concept
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RNA, Untranslated
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Concept
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DEAD-box RNA Helicases
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Concept
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RNA-Binding Protein FUS
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Concept
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RNA, Small Interfering
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Concept
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RNA Isoforms
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Concept
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Ligases
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Concept
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RNA, Ribosomal
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Concept
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Sequence Analysis, RNA
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Concept
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RNA Stability
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Academic Article
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The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
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Academic Article
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Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
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Academic Article
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Ring finger protein 43 as a new target for cancer immunotherapy.
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Academic Article
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Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice.
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Academic Article
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Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
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Academic Article
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A SNP in the ABCC11 gene is the determinant of human earwax type.
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Academic Article
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Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
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Academic Article
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Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
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Academic Article
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Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
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Academic Article
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Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
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Academic Article
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Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.
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Academic Article
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Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
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Academic Article
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Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.
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Academic Article
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Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
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Academic Article
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Common variation in GPC5 is associated with acquired nephrotic syndrome.
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Academic Article
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Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
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Academic Article
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ADAM8 as a novel serological and histochemical marker for lung cancer.
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Academic Article
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Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese.
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Academic Article
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Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
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Academic Article
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Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
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Academic Article
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Multiple loci are associated with white blood cell phenotypes.
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Academic Article
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Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
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Academic Article
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Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
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Academic Article
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A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
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Academic Article
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Pharmacogenomics of tamoxifen: roles of drug metabolizing enzymes and transporters.
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Academic Article
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Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer.
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Academic Article
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IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.
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Academic Article
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High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population.
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Academic Article
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Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer.
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Academic Article
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Activation of placenta-specific transcription factor distal-less homeobox 5 predicts clinical outcome in primary lung cancer patients.
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Academic Article
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IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
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Academic Article
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ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations.
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Academic Article
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Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis.
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Academic Article
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Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
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Academic Article
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Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
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Academic Article
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Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
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Academic Article
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Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
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Academic Article
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Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction.
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Academic Article
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Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
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Academic Article
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Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
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Academic Article
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Involvement of C12orf32 overexpression in breast carcinogenesis.
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Academic Article
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Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
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Academic Article
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Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes.
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Academic Article
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Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.
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Academic Article
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Functional haplotypes of IL-12B are associated with childhood atopic asthma.
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Academic Article
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Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.
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Academic Article
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Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
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Academic Article
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EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth.
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Academic Article
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Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs.
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Academic Article
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Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
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Academic Article
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Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.
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Academic Article
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Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
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Academic Article
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Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
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Academic Article
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Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer.
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Academic Article
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A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
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Academic Article
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Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
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Academic Article
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Genome-wide gene expression profiles of clear cell renal cell carcinoma: identification of molecular targets for treatment of renal cell carcinoma.
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Academic Article
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Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer.
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Academic Article
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ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.
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Academic Article
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Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
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Academic Article
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Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.
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Academic Article
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Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
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Academic Article
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HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy.
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Academic Article
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TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
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Academic Article
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Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia.
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Academic Article
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Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
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Academic Article
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Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
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Academic Article
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Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
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Academic Article
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Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis.
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Academic Article
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Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
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Academic Article
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Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
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Academic Article
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Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
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Academic Article
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The Xq22 inversion breakpoint interrupted a novel Ras-like GTPase gene in a patient with Duchenne muscular dystrophy and profound mental retardation.
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Academic Article
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Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell.
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Academic Article
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Comparison of gene expression profiles between Opisthorchis viverrini and non-Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma.
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Academic Article
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Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
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Academic Article
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Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
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Academic Article
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Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis.
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Academic Article
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Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
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Academic Article
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The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
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Academic Article
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The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer.
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Academic Article
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ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
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Academic Article
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Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.
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Academic Article
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A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
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Academic Article
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Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
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Academic Article
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Oncogenic role of NALP7 in testicular seminomas.
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Academic Article
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Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.
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Academic Article
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Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
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Academic Article
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[SNP collection, pharmacogenomics, and the future of drug therapy].
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Academic Article
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Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.
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Academic Article
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Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
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Academic Article
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Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition.
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Academic Article
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Expression profiles of two types of human knee-joint cartilage.
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Academic Article
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High-density SNP map of human ITR, a gene associated with vascular remodeling.
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Academic Article
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Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
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Academic Article
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SNPs in BRAP associated with risk of myocardial infarction in Asian populations.
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Academic Article
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PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
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Academic Article
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Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
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Academic Article
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A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
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Academic Article
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Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
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Academic Article
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Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis.
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Academic Article
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Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
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Academic Article
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Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
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Academic Article
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WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
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Academic Article
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hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
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Academic Article
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A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.
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Academic Article
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Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
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Academic Article
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Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
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Academic Article
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Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
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Academic Article
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Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
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Academic Article
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Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
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Academic Article
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Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
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Academic Article
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Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
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Academic Article
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Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer.
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Academic Article
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Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
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Academic Article
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Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
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Academic Article
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MRG-binding protein contributes to colorectal cancer development.
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Academic Article
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Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit.
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Academic Article
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Enhanced SMYD3 expression is essential for the growth of breast cancer cells.
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Academic Article
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Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
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Academic Article
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ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
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Academic Article
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A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
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Academic Article
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Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
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Academic Article
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The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
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Academic Article
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Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
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Academic Article
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VAV3 mediates resistance to breast cancer endocrine therapy.
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Academic Article
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A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
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Academic Article
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The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
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Academic Article
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Detection of novel cancer-testis antigen-specific T-cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carcinoma.
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Academic Article
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Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1.
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Academic Article
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Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
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Academic Article
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Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.
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Academic Article
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Identification of semaphorin3B as a direct target of p53.
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Academic Article
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Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
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Academic Article
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A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.
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Academic Article
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Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas.
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Academic Article
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The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
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Academic Article
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Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
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Academic Article
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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
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Academic Article
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Expression profile analysis of colon cancer cells in response to sulindac or aspirin.
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Academic Article
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Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.
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Academic Article
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Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.
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Academic Article
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Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
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Academic Article
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Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues.
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Academic Article
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Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
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Academic Article
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Oncogenic role of MPHOSPH1, a cancer-testis antigen specific to human bladder cancer.
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Academic Article
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Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
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Academic Article
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Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
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Academic Article
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DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
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Academic Article
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Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.
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Academic Article
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PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents.
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Academic Article
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T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
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Academic Article
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Identification of COX17 as a therapeutic target for non-small cell lung cancer.
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Academic Article
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Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
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Academic Article
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Regulation of iron homeostasis by the p53-ISCU pathway.
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Academic Article
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SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
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Academic Article
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Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases.
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Academic Article
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Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer.
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Academic Article
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Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells.
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Academic Article
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HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.
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Academic Article
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Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.
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Academic Article
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Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
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Academic Article
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Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.
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Academic Article
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From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma.
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Academic Article
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Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.
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Academic Article
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Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown.
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Academic Article
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Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
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Academic Article
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p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.
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Academic Article
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The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
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Academic Article
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Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL).
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Academic Article
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Construction and characterization of a vestibular-specific cDNA library using T7-based RNA amplification.
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Academic Article
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TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
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Academic Article
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GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
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Academic Article
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Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection.
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Academic Article
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The Transcriptional Landscape of p53 Signalling Pathway.
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Academic Article
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Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
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Academic Article
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The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
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Academic Article
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A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
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Academic Article
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Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.
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Academic Article
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MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
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Academic Article
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The GALNT6-LGALS3BP axis promotes breast cancer cell growth.
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Concept
|
RNA Splicing Factors
|
Concept
|
Nedd4 Ubiquitin Protein Ligases
|
Concept
|
RNA, Long Noncoding
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Concept
|
ATP Binding Cassette Transporter 1
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Academic Article
|
SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
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Academic Article
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Identification of RNF213 as a Potential Suppressor of Local Invasion in Intrahepatic Cholangiocarcinoma.
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