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Activation of inhibitors by sortase triggers irreversible modification of the active site.
Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization.
Flexibility of the DNA-binding domains of trp repressor.
Crystal structure of trp repressor/operator complex at atomic resolution.
Virtual high-throughput ligand screening.
Insights into PG-binding, conformational change, and dimerization of the OmpA C-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi.
A novel polyamine allosteric site of SpeG from Vibrio cholerae is revealed by its dodecameric structure.
Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG.
Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events.
Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2.
Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2.
Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB.
Protein Conformation, alpha-Helical
Protein Conformation, beta-Strand