Item Type | Name |
Concept
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Hydroxymethylglutaryl-CoA Reductase Inhibitors
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Academic Article
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Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia.
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Academic Article
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Efficacy and safety of lovastatin in adolescent males with heterozygous familial hypercholesterolemia: a randomized controlled trial.
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Academic Article
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The lipid-lowering effects of atorvastatin, a new HMG-CoA reductase inhibitor: results of a randomized, double-masked study.
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Academic Article
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A comparison of simvastatin and atorvastatin up to maximal recommended doses in a large multicenter randomized clinical trial.
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Academic Article
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Safety profiles for the HMG-CoA reductase inhibitors: treatment and trust.
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Academic Article
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Efficacy and safety of combination simvastatin and colesevelam in patients with primary hypercholesterolemia.
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Academic Article
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A look to the future: new treatment guidelines and a perspective on statins.
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Academic Article
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Effects of high-dose simvastatin on adrenal and gonadal steroidogenesis in men with hypercholesterolemia.
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Academic Article
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Lipid and apolipoprotein ratios: association with coronary artery disease and effects of rosuvastatin compared with atorvastatin, pravastatin, and simvastatin.
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Academic Article
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Management of hypercholesterolaemia in postmenopausal women.
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Academic Article
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Combination therapy for dyslipidemia: safety and regulatory considerations.
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Academic Article
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Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial).
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Academic Article
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Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II).
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Academic Article
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Effects of simvastatin, an HMG-CoA reductase inhibitor, in patients with hypertriglyceridemia.
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Academic Article
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A multicenter, randomized, double-blind clinical trial comparing the low-density lipoprotein cholesterol-lowering ability of lovastatin 10, 20, and 40 mg/d with fluvastatin 20 and 40 mg/d.
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Academic Article
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Possible differences between fibrates in pharmacokinetic interactions with statins.
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Academic Article
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Combination lipid-lowering therapy in diabetes.
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Academic Article
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Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia.
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Academic Article
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Comparative effects of lipid-lowering therapies.
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Academic Article
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Lipid management and the elderly.
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Academic Article
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Aggressive versus moderate lipid-lowering therapy in hypercholesterolemic postmenopausal women: Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES).
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Academic Article
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Rosuvastatin safety: lessons from the FDA review and post-approval surveillance.
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Academic Article
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Effects of colesevelam hydrochloride on low-density lipoprotein cholesterol and high-sensitivity C-reactive protein when added to statins in patients with hypercholesterolemia.
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Academic Article
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Ezetimibe: a novel option for lowering cholesterol.
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Academic Article
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Reducing residual risk for patients on statin therapy: the potential role of combination therapy.
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Academic Article
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Statin/fibrate combination in patients with metabolic syndrome or diabetes: evaluating the risks of pharmacokinetic drug interactions.
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Academic Article
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Striated muscle safety of ezetimibe/simvastatin (Vytorin).
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Academic Article
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Statin safety: an assessment using an administrative claims database.
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Academic Article
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Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia.
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Academic Article
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Lipid-lowering effects of statins: a comparative review.
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Academic Article
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Efficacy and tolerability of adding prescription omega-3 fatty acids 4 g/d to simvastatin 40 mg/d in hypertriglyceridemic patients: an 8-week, randomized, double-blind, placebo-controlled study.
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Academic Article
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High-density lipoprotein metabolism: potential therapeutic targets.
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Academic Article
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Reducing the residual risk of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor therapy with combination therapy.
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Academic Article
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The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study.
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Academic Article
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Comparative effectiveness of rosuvastatin versus other statin therapies in patients at increased risk of failure to achieve low-density lipoprotein goals.
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Academic Article
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Should every patient with diabetes receive a statin?
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Academic Article
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The editor's roundtable: lipid management beyond statins-reducing residual cardiovascular risk.
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Academic Article
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Reporting rate of rhabdomyolysis with fenofibrate + statin versus gemfibrozil + any statin.
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Academic Article
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A review of lipid management in primary and secondary prevention.
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Academic Article
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Focused atorvastatin therapy in managed-care patients with coronary heart disease and CKD.
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Academic Article
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Titration patterns with rosuvastatin as compared with other statins in clinical practice: a retrospective observational cohort study using an electronic medical record database.
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Academic Article
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Combination therapy in the management of complex dyslipidemias.
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Academic Article
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Lipoprotein management in patients with cardiometabolic risk: consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation.
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Academic Article
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The editor's roundtable: the JUPITER trial--initial results and clinical implications.
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Academic Article
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Treating dyslipidemia in high-risk patients: case reviews and discussion.
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Academic Article
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Management of dyslipidemia in patients with complicated metabolic syndrome.
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Academic Article
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Statin safety: an appraisal from the adverse event reporting system.
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Academic Article
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Combination therapy with ezetimibe and simvastatin to achieve aggressive LDL reduction.
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Academic Article
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Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients.
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Academic Article
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Considerations in the treatment of dyslipidemia associated with chronic kidney failure and renal transplantation.
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Academic Article
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Low-density lipoprotein cholesterol reduction and goal achievement with ezetimibe/simvastatin versus atorvastatin or rosuvastatin in patients with diabetes, metabolic syndrome, or neither disease, stratified by National Cholesterol Education Program risk category.
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Academic Article
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Efficacy and safety of fenofibric acid co-administered with low- or moderate-dose statin in patients with mixed dyslipidemia and type 2 diabetes mellitus: results of a pooled subgroup analysis from three randomized, controlled, double-blind trials.
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Academic Article
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Low high-density lipoprotein cholesterol and increased cardiovascular disease risk: an analysis of statin clinical trials.
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Academic Article
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Underappreciated opportunities for low-density lipoprotein management in patients with cardiometabolic residual risk.
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Academic Article
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Safety of aggressive lipid management.
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Academic Article
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The use of colesevelam hydrochloride in the treatment of dyslipidemia: a review.
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Academic Article
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Targeting high-density lipoprotein cholesterol in the management of cardiovascular disease.
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Academic Article
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High-dose statin therapy: benefits and safety in aggressive lipid lowering.
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Academic Article
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Statin and ezetimibe combination therapy in cardiovascular disease.
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Academic Article
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Counterpoint: Low-density lipoprotein cholesterol goals in patients with diabetes are adequately based on evidence.
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Academic Article
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High-dose statins in acute coronary syndromes.
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Academic Article
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Comparison of low-density lipoprotein cholesterol reduction after switching patients on other statins to rosuvastatin or simvastatin in a real-world clinical practice setting.
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Academic Article
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Clinical utility of inflammatory markers and advanced lipoprotein testing: advice from an expert panel of lipid specialists.
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Academic Article
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One-year efficacy and safety of rosuvastatin + fenofibric acid combination therapy in patients with mixed dyslipidemia: evaluation of dose response.
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Academic Article
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The use of high-sensitivity assays for C-reactive protein in clinical practice.
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Academic Article
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Evaluation of a new formulation of fenofibric acid, ABT-335, co-administered with statins : study design and rationale of a phase III clinical programme.
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Academic Article
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Lp-PLA2: A new target for statin therapy.
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Academic Article
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Pharmacokinetic interactions between statins and fibrates.
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Academic Article
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Effects of combination therapy with rosuvastatin and fenofibric acid in patients with mixed dyslipidemia and high-sensitivity C-reactive protein (= 2 mg/L). cmb@bcm.tmc.edu.
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Academic Article
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Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor.
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Academic Article
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Fluvastatin administration at bedtime versus with the evening meal: a multicenter comparison of bioavailability, safety, and efficacy.
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Academic Article
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Hypercholesterolemia treatment patterns and low-density lipoprotein cholesterol monitoring in patients with a diagnosis of atherosclerosis in clinical practice.
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Academic Article
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Apolipoprotein measurements: is more widespread use clinically indicated?
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Academic Article
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Efficacy and tolerability of atorvastatin/fenofibrate fixed-dose combination tablet compared with atorvastatin and fenofibrate monotherapies in patients with dyslipidemia: a 12-week, multicenter, double-blind, randomized, parallel-group study.
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Academic Article
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Apolipoprotein A-I therapy promise, challenges, and disappointment.
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Academic Article
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The editor's roundtable: JUPITER follow-up.
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Academic Article
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Safety and efficacy of ezetimibe added on to rosuvastatin 5 or 10 mg versus up-titration of rosuvastatin in patients with hypercholesterolemia (the ACTE Study).
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Academic Article
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Treatment of the elderly with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors: focus on drug interactions.
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Academic Article
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Risk for myopathy with statin therapy in high-risk patients.
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Academic Article
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Newer pharmaceutical agents to treat lipid disorders.
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Academic Article
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Differential effects of simvastatin and atorvastatin on high-density lipoprotein cholesterol and apolipoprotein A-I are consistent across hypercholesterolemic patient subgroups.
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Academic Article
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Torcetrapib/atorvastatin combination therapy.
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Academic Article
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Effectiveness of statins in Medicare-eligible patients and patients < 65 years using clinical practice data.
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Academic Article
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Rosuvastatin in elderly patients.
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Academic Article
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Long-term safety and efficacy of a combination of niacin extended release and simvastatin in patients with dyslipidemia: the OCEANS study.
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Academic Article
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Is it over for ezetimibe?
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Academic Article
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Is LDL-C passed its prime? The emerging role of non-HDL, LDL-P, and ApoB in CHD risk assessment.
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Academic Article
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Efficacy and safety of ABT-335 (fenofibric acid) in combination with rosuvastatin in patients with mixed dyslipidemia: a phase 3 study.
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Academic Article
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A review of the current status of the management of mixed dyslipidemia associated with diabetes mellitus and metabolic syndrome.
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Academic Article
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Concomitant use of statins and CYP3A4 inhibitors in administrative claims and electronic medical records databases.
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Academic Article
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Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in mouse uterine epithelial cells.
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Academic Article
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Fluvastatin Long-Term Extension Trial (FLUENT): summary of efficacy and safety.
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Academic Article
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Controversy surrounding the safety of cerivastatin.
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Academic Article
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Dysfunctional HDL: a novel important diagnostic and therapeutic target in cardiovascular disease?
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Academic Article
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Pharmacotherapy: Implications of high-dose statin link with incident diabetes.
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Academic Article
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Risk of hospitalized rhabdomyolysis associated with lipid-lowering drugs in a real-world clinical setting.
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Academic Article
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Cost effectiveness of treatment to National Cholesterol Education Panel (NCEP) targets with HMG-CoA reductase inhibitors. Trial design.
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Academic Article
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Addition of omega-3 carboxylic acids to statin therapy in patients with persistent hypertriglyceridemia.
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Academic Article
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Dyslipidaemia: PCSK9 antibodies: a dividend of the genomics revolution.
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Academic Article
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Combination therapy with statins: who benefits?
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Academic Article
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Genetics and causality of triglyceride-rich lipoproteins in atherosclerotic cardiovascular disease.
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Academic Article
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Effects of anacetrapib on plasma lipids in specific patient subgroups in the DEFINE (Determining the Efficacy and Tolerability of CETP INhibition with AnacEtrapib) trial.
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Academic Article
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A highly bioavailable omega-3 free fatty acid formulation improves the cardiovascular risk profile in high-risk, statin-treated patients with residual hypertriglyceridemia (the ESPRIT trial).
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Academic Article
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Comparison of the lipid-lowering effects of pitavastatin 4 mg versus pravastatin 40 mg in adults with primary hyperlipidemia or mixed (combined) dyslipidemia: a Phase IV, prospective, US, multicenter, randomized, double-blind, superiority trial.
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Academic Article
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Overcoming toxicity and side-effects of lipid-lowering therapies.
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Academic Article
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The efficacy of colesevelam HCl in the treatment of heterozygous familial hypercholesterolemia in pediatric and adult patients.
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Academic Article
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Effects of fenofibric acid on carotid intima-media thickness in patients with mixed dyslipidemia on atorvastatin therapy: randomized, placebo-controlled study (FIRST).
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Academic Article
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Statin intolerance - an attempt at a unified definition. Position paper from an International Lipid Expert Panel.
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Academic Article
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Beta-2 Agonism: A Potential Therapeutic Target for Dyslipidemia.
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Academic Article
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Effects of omega-3 carboxylic acids on lipoprotein particles and other cardiovascular risk markers in high-risk statin-treated patients with residual hypertriglyceridemia: a randomized, controlled, double-blind trial.
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Academic Article
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Changing characteristics of statin-related cIMT trials from 1988 to 2006.
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Academic Article
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The Risk of Hepatotoxicity, New Onset Diabetes and Rhabdomyolysis in the Era of High-Intensity Statin Therapy: Does Statin Type Matter?
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Academic Article
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Intensive statin therapy in India: Demonstrating efficacy and safety.
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Academic Article
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Omega-3 carboxylic acids monotherapy and combination with statins in the management of dyslipidemia.
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Academic Article
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Development and Content Validity of the Statin Experience Assessment Questionnaire (SEAQ)©.
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Academic Article
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AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF DYSLIPIDEMIA AND PREVENTION OF CARDIOVASCULAR DISEASE.
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Academic Article
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Assessment of pharmacokinetic interaction between omega-3 carboxylic acids and the statins rosuvastatin and simvastatin: Results of 2 phase I studies in healthy volunteers.
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Academic Article
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Assessment of omega-3 carboxylic acids in statin-treated patients with high levels of triglycerides and low levels of high-density lipoprotein cholesterol: Rationale and design of the STRENGTH trial.
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Academic Article
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Can We Cure Atherosclerosis?
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Academic Article
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Efficacy and Safety of Alirocumab in High-Risk Patients With Clinical Atherosclerotic Cardiovascular Disease and/or Heterozygous Familial Hypercholesterolemia (from 5 Placebo-Controlled ODYSSEY Trials).
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Academic Article
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Triglyceride-rich lipoprotein cholesterol (TRL-C): the ugly stepsister of LDL-C.
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Academic Article
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Associations between lower levels of low-density lipoprotein cholesterol and cardiovascular events in very high-risk patients: Pooled analysis of nine ODYSSEY trials of alirocumab versus control.
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Academic Article
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Comparing remnant lipoprotein cholesterol measurement methods to evaluate efficacy of ezetimibe/statin vs statin therapy.
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Academic Article
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The Battle of the HDL Subfractions.
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Academic Article
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Recent advances and emerging therapies in management of dyslipidemias.
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Academic Article
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Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk: The STRENGTH Randomized Clinical Trial.
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Academic Article
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How I treat statin-associated side effects in an outpatient setting.
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Academic Article
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Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Management of Dyslipidemia and Prevention of Cardiovascular Disease Algorithm - 2020 Executive Summary.
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Academic Article
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The clinical black, white, and gray lessons.
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Academic Article
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Lipid lowering effects of the CETP inhibitor obicetrapib in combination with high-intensity statins: a randomized phase 2 trial.
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Academic Article
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Obicetrapib plus ezetimibe as an adjunct to high-intensity statin therapy: A randomized phase 2 trial.
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Academic Article
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Obicetrapib: Reversing the Tide of CETP Inhibitor Disappointments.
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Academic Article
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Obicetrapib on top of maximally tolerated lipid-modifying therapies in participants with or at high risk for atherosclerotic cardiovascular disease: rationale and designs of BROADWAY and BROOKLYN.
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Academic Article
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Cholesteryl Ester Transfer Protein Inhibition Reduces Major Adverse Cardiovascular Events by Lowering Apolipoprotein B Levels.
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Academic Article
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A randomized controlled trial of add-on naproxen, simvastatin and their combination for the treatment of schizophrenia or schizoaffective disorder.
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