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Clark, Marcus Ramsay
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Clark, Marcus Ramsay
Receptors, Antigen, B-Cell
Receptors, Antigen, T-Cell
The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways.
Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha.
A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling.
Selection of B lymphocytes in the periphery is determined by the functional capacity of the B cell antigen receptor.
B cell antigen receptor signaling and internalization are mutually exclusive events.
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
Regulation of lymphocyte progenitor survival by the proapoptotic activities of Bim and Bid.
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.
Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor.
Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells.
Igalpha: B all that you can B.
The control and facilitation of MHC class II antigen processing by the BCR.
Ig alpha and Ig beta are required for efficient trafficking to late endosomes and to enhance antigen presentation.
The pre-B cell receptor in B cell development: recent advances, persistent questions and conserved mechanisms.
PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction.
Ig? ubiquitination activates PI3K signals required for endosomal sorting.
CXCR4 signaling directs Igk recombination and the molecular mechanisms of late B lymphopoiesis.
B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
Asymmetrical forward and reverse developmental trajectories determine molecular programs of B cell antigen receptor editing.
Receptors Antigen B Cell