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One or more keywords matched the following properties of Kron, Stephen J.
keywords Checkpoints, Cell Cycle
overview The Kron laboratory is a diverse and collaborative group of cell biologists, geneticists, biochemists, chemists and computer scientists. Our current basic research and technology efforts include 1) defining roles for chromatin dynamics and cell cycle regulation in DNA damage checkpoint response and cellular senescence, 2) dissecting cross-talk between metabolism and DNA damage response, 3) developing novel molecular assays to interrogate cell signaling in cancer, and 4) implementing novel mass spectrometry approaches to enable quantitative proteomics. We also pursue translational projects directed at 1) discovering inhibitors of cellular response to DNA double strand breaks as an approach to radiosensitization, 2) examining DNA damage and repair in tissues and tumors, and 3) exploiting DNA damage responses to induce anti-tumor immune responses.
One or more keywords matched the following items that are connected to Kron, Stephen J.
Item TypeName
Concept Cell Cycle
Concept Cell Cycle Proteins
Concept Cell Cycle Checkpoints
Concept G1 Phase Cell Cycle Checkpoints
Academic Article Budding yeast morphogenesis: signalling, cytoskeleton and cell cycle.
Academic Article Regulation of G2/M progression by the STE mitogen-activated protein kinase pathway in budding yeast filamentous growth.
Academic Article NuA4 subunit Yng2 function in intra-S-phase DNA damage response.
Academic Article Robust G1 checkpoint arrest in budding yeast: dependence on DNA damage signaling and repair.
Academic Article Cell cycle control of yeast filamentous growth.
Academic Article Depression of Saccharomyces cerevisiae invasive growth on non-glucose carbon sources requires the Snf1 kinase.
Academic Article Mutations in the yeast cyclin-dependent kinase Cdc28 reveal a role in the spindle assembly checkpoint.
Academic Article Enhanced cell polarity in mutants of the budding yeast cyclin-dependent kinase Cdc28p.
Academic Article Asynchronous cell cycle and asymmetric vacuolar inheritance in true hyphae of Candida albicans.
Academic Article Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.
Academic Article CDK Pho85 targets CDK inhibitor Sic1 to relieve yeast G1 checkpoint arrest after DNA damage.
Academic Article Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide.
Academic Article Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping.
Academic Article Control of the yeast cell cycle with a photocleavable alpha-factor analogue.
Academic Article Non-catalytic function for ATR in the checkpoint response.
Academic Article Symmetric cell division in pseudohyphae of the yeast Saccharomyces cerevisiae.
Academic Article Morphogenesis signaling components influence cell cycle regulation by cyclin dependent kinase.
Academic Article A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1.
Academic Article Regulation of cation transport in Saccharomyces cerevisiae by the salt tolerance gene HAL3.
Academic Article Yeast cell death during DNA damage arrest is independent of caspase or reactive oxygen species.
Academic Article Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling.
Academic Article CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression.
Academic Article DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast.
Academic Article The yin and yang of cyclin control by nutrients.
Academic Article Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors.
Academic Article The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair.
Academic Article Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex.
Academic Article Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence.
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  • Cell Cycle