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overview The Gilad lab focuses on studying genetic and regulatory differences between humans and our close evolutionary relatives. Our long term goal is to identify the genetic basis of human-specific traits, including genetic variation that underlies higher susceptibility to certain diseases and disorders in humans than in other primates.
One or more keywords matched the following items that are connected to Gilad, Yoav
Item TypeName
Concept Primates
Academic Article Sex-specific and lineage-specific alternative splicing in primates.
Academic Article Regulatory element copy number differences shape primate expression profiles.
Academic Article Comparative studies of gene expression and the evolution of gene regulation.
Academic Article Functional comparison of innate immune signaling pathways in primates.
Academic Article Gene expression differences among primates are associated with changes in a histone epigenetic modification.
Academic Article Comparative RNA sequencing reveals substantial genetic variation in endangered primates.
Academic Article Gene regulation in primates evolves under tissue-specific selection pressures.
Academic Article Epigenetic modifications are associated with inter-species gene expression variation in primates.
Academic Article Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes.
Academic Article Primate transcript and protein expression levels evolve under compensatory selection pressures.
Academic Article Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence.
Academic Article Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs.
Academic Article Reorganization of 3D genome structure may contribute to gene regulatory evolution in primates.
Academic Article Prime time for primate functional genomics.
Academic Article Evolutionary insights into primate skeletal gene regulation using a comparative cell culture model.
Grant Development of iPSCs for comparative genomics in primates
Grant The evolution of human specific regulatory pathways
Grant Natural Selection on Gene Regulation in Humans
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  • Primates