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Karczmar, Gregory

One or more keywords matched the following properties of Karczmar, Gregory

Property	Value
keywords	Breast cancer screening with MRI
overview	I have developed new approaches to functional and anatomic magnetic resonance imaging for over 30 years. I’ve applied these methods to improve detection and accurate diagnosis of cancer, and monitor cancer response to therapy. I am the Director of Magnetic Resonance Imaging Research at the University of Chicago, and Co-Director of the Advanced Imaging Program of the University of Chicago Comprehensive Cancer center. I’ve collaborated with our outstanding mammographic group and medical physics colleagues for many years to build internationally recognized research program in quantitative breast cancer MR imaging – which parallels and compliments a leading clinical program in breast cancer diagnosis and management. Similarly, I’ve collaborated with Dr. Oto and others to develop a leading translational research program focused on improving prostate cancer screening with MRI, and using MRI to guide therapye. With these collaborators, I’ve made pioneering contributions to MRI methods that improve prostate and breast cancer diagnosis and treatment. My research includes use of pre-clinical methods for breast and prostate cancer to improve understanding of cancer biology and guide the development of improved clinical methods.

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Value

keywords

Breast cancer screening with MRI

overview

I have developed new approaches to functional and anatomic magnetic resonance imaging for over 30 years. I’ve applied these methods to improve detection and accurate diagnosis of cancer, and monitor cancer response to therapy. I am the Director of Magnetic Resonance Imaging Research at the University of Chicago, and Co-Director of the Advanced Imaging Program of the University of Chicago Comprehensive Cancer center. I’ve collaborated with our outstanding mammographic group and medical physics colleagues for many years to build internationally recognized research program in quantitative breast cancer MR imaging – which parallels and compliments a leading clinical program in breast cancer diagnosis and management. Similarly, I’ve collaborated with Dr. Oto and others to develop a leading translational research program focused on improving prostate cancer screening with MRI, and using MRI to guide therapye. With these collaborators, I’ve made pioneering contributions to MRI methods that improve prostate and breast cancer diagnosis and treatment. My research includes use of pre-clinical methods for breast and prostate cancer to improve understanding of cancer biology and guide the development of improved clinical methods.

One or more keywords matched the following items that are connected to Karczmar, Gregory

Item Type	Name
Concept	Breast Diseases
Concept	Breast Neoplasms
Concept	Breast
Concept	Carcinoma, Ductal, Breast
Academic Article	Fast spectroscopic imaging of water and fat resonances to improve the quality of MR images.
Academic Article	Spectrally inhomogeneous effects of contrast agents in breast lesion detected by high spectral and spatial resolution MRI.
Academic Article	Breast MR imaging with high spectral and spatial resolutions: preliminary experience.
Academic Article	Reduction of spectral ghost artifacts in high-resolution echo-planar spectroscopic imaging of water and fat resonances.
Academic Article	The effect of varying spectral resolution on the quality of high spectral and spatial resolution magnetic resonance images of the breast.
Academic Article	Fourier components of inhomogeneously broadened water resonances in breast: a new source of MRI contrast.
Academic Article	High spectral and spatial resolution MRI of breast lesions: preliminary clinical experience.
Academic Article	Fat suppression with spectrally selective inversion vs. high spectral and spatial resolution MRI of breast lesions: qualitative and quantitative comparisons.
Academic Article	Differentiation between benign and malignant breast lesions detected by bilateral dynamic contrast-enhanced MRI: a sensitivity and specificity study.
Academic Article	DCEMRI of breast lesions: is kinetic analysis equally effective for both mass and nonmass-like enhancement?
Academic Article	Magnetic resonance imaging of the natural history of in situ mammary neoplasia in transgenic mice: a pilot study.
Academic Article	Relating dose of contrast media administered to uptake and washout of malignant lesions on DCEMRI of the breast.
Academic Article	Kinetic curves of malignant lesions are not consistent across MRI systems: need for improved standardization of breast dynamic contrast-enhanced MRI acquisition.
Academic Article	Echo-planar spectroscopic imaging (EPSI) of the water resonance structure in human breast using sensitivity encoding (SENSE).
Academic Article	Clinical implementation of a multislice high spectral and spatial resolution-based MRI sequence to achieve unilateral full-breast coverage.
Academic Article	Fourier component imaging of water resonance in the human breast provides markers for malignancy.
Academic Article	Characterizing early contrast uptake of ductal carcinoma in situ with high temporal resolution dynamic contrast-enhanced MRI of the breast: a pilot study.
Academic Article	Diagnosis of suspicious breast lesions using an empirical mathematical model for dynamic contrast-enhanced MRI.
Academic Article	Normal parenchymal enhancement patterns in women undergoing MR screening of the breast.
Academic Article	The diverse pathology and kinetics of mass, nonmass, and focus enhancement on MR imaging of the breast.
Academic Article	In vivo MRI of early stage mammary cancers and the normal mouse mammary gland.
Academic Article	Comparing post-operative human breast specimen radiograph and MRI in lesion margin and volume assessment.
Academic Article	Non-contrast enhanced MRI for evaluation of breast lesions: comparison of non-contrast enhanced high spectral and spatial resolution (HiSS) images versus contrast enhanced fat-suppressed images.
Academic Article	Measurement of differences in pO2 in response to perfluorocarbon/carbogen in FSa and NFSa murine fibrosarcomas with low-frequency electron paramagnetic resonance oximetry.
Academic Article	Pure ductal carcinoma in situ: kinetic and morphologic MR characteristics compared with mammographic appearance and nuclear grade.
Academic Article	Do we really need contrast agents?
Academic Article	Classification of breast lesions pre-contrast injection using water resonance lineshape analysis.
Academic Article	Mammary cancer initiation and progression studied with magnetic resonance imaging.
Academic Article	Potential of computer-aided diagnosis of high spectral and spatial resolution (HiSS) MRI in the classification of breast lesions.
Academic Article	Comparison of dynamic contrast-enhanced MRI parameters of breast lesions at 1.5 and 3.0?T: a pilot study.
Academic Article	Residual analysis of the water resonance signal in breast lesions imaged with high spectral and spatial resolution (HiSS) MRI: a pilot study.
Academic Article	Preliminary assessment of dispersion versus absorption analysis of high spectral and spatial resolution magnetic resonance images in the diagnosis of breast cancer.
Academic Article	Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis.
Academic Article	B1 and T1 mapping of the breast with a reference tissue method.
Academic Article	Ultrafast Bilateral DCE-MRI of the Breast with Conventional Fourier Sampling: Preliminary Evaluation of Semi-quantitative Analysis.
Academic Article	Kinetic Analysis of Benign and Malignant Breast Lesions With Ultrafast Dynamic Contrast-Enhanced MRI: Comparison With Standard Kinetic Assessment.
Academic Article	Breast density estimation from high spectral and spatial resolution MRI.
Academic Article	Fast bilateral breast coverage with high spectral and spatial resolution (HiSS) MRI at 3T.
Academic Article	Value of breast MRI for patients with a biopsy showing atypical ductal hyperplasia (ADH).
Academic Article	MRI ductography of contrast agent distribution and leakage in normal mouse mammary ducts and ducts with in situ cancer.
Academic Article	DCEMRI of breast lesions: Is kinetic analysis equally effective for both mass and nonmass-like enhancement?
Academic Article	MRI reveals increased tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer.
Academic Article	Ultrafast Dynamic Contrast-Enhanced Breast MRI: Kinetic Curve Assessment Using Empirical Mathematical Model Validated with Histological Microvessel Density.
Academic Article	Dynamic field-of-view imaging to increase temporal resolution in the early phase of contrast media uptake in breast DCE-MRI: A feasibility study.
Academic Article	Quantitative analysis of vascular properties derived from ultrafast DCE-MRI to discriminate malignant and benign breast tumors.
Academic Article	Fast Temporal Resolution Dynamic Contrast-Enhanced MRI: Histogram Analysis Versus Visual Analysis for Differentiating Benign and Malignant Breast Lesions.
Academic Article	Intensive Surveillance with Biannual Dynamic Contrast-Enhanced Magnetic Resonance Imaging Downstages Breast Cancer in BRCA1 Mutation Carriers.
Academic Article	Low-dose imaging technique (LITE) MRI: initial experience in breast imaging.
Academic Article	Patient-Specific Characterization of Breast Cancer Hemodynamics Using Image-Guided Computational Fluid Dynamics.
Academic Article	Discrimination of benign from malignant breast lesions in dense breasts with model-based analysis of regions-of-interest using directional diffusion-weighted images.
Academic Article	Magnetic resonance angiography reveals increased arterial blood supply and tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer.
Academic Article	Robustness of radiomic features of benign breast lesions and hormone receptor positive/HER2-negative cancers across DCE-MR magnet strengths.
Academic Article	Enhancement-constrained acceleration: A robust reconstruction framework in breast DCE-MRI.
Academic Article	Differences Between Ipsilateral and Contralateral Early Parenchymal Enhancement Kinetics Predict Response of Breast Cancer to Neoadjuvant Therapy.
Academic Article	Towards Patient-Specific Optimization of Neoadjuvant Treatment Protocols for Breast Cancer Based on Image-Guided Fluid Dynamics.
Academic Article	Safely reducing unnecessary benign breast biopsies by applying non-mass and DWI directional variance filters to ADC thresholding.
Academic Article	Standardization of Breast Dynamic Contrast-enhanced MRI Signal with Application to the Assessment of Background Parenchymal Enhancement Rate.
Concept	Breast Density
Concept	Triple Negative Breast Neoplasms
Grant	Dynamic Spatial and Spectral, Contrast Enhanced MRI of *
Grant	Quantitative MRI for Predicting Response of Breast Cancer to Neoadjuvant Therapy
Grant	Assessment of Breast Cancer Risk with High Spectral and Spatial Resolution MRI
Grant	High Spectral &Spatial Resolution MRI of Rodent Tumors
Grant	3T MRI Scanner for multidisciplinary imaging and image-guided therapy
Grant	Fast Spectroscopic MR Imaging of Breast Cancer
Grant	MRI of Early Non-invasive Rodent Mammary Cancers
Grant	High Spectral/Spatial Resolution Imaging Breast Cancer
Grant	Breast Cancer Screening with Quantitative Ultra-Fast DCEMRI and Clinical Risk Assessment
Academic Article	Pharmacokinetic Analysis of Enhancement-Constrained Acceleration (ECA) reconstruction-based high temporal resolution breast DCE-MRI.
Academic Article	Bilateral asymmetry of quantitative parenchymal kinetics at ultrafast DCE-MRI predict response to neoadjuvant chemotherapy in patients with HER2+ breast cancer.
Academic Article	External Evaluation of a Mammography-based Deep Learning Model for Predicting Breast Cancer in an Ethnically Diverse Population.
Grant	Chicago Alternative Prevention Study for BReast CAncer in Diverse Populations of High-Risk Women (CAPSBRACA)

Search Criteria

Breast