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Awad, Issam

One or more keywords matched the following items that are connected to Awad, Issam

Item Type	Name
Academic Article	Biallelic somatic and germ line CCM1 truncating mutations in a cerebral cavernous malformation lesion.
Academic Article	Mutational analysis of 206 families with cavernous malformations.
Academic Article	Spectrum of genotype and clinical manifestations in cerebral cavernous malformations.
Academic Article	Advanced magnetic resonance imaging of cerebral cavernous malformations: part II. Imaging of lesions in murine models.
Academic Article	Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.
Academic Article	A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
Academic Article	Cerebral cavernous malformations: somatic mutations in vascular endothelial cells.
Academic Article	Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease.
Academic Article	Different spectra of genomic deletions within the CCM genes between Italian and American CCM patient cohorts.
Academic Article	Cerebral cavernous malformations as a disease of vascular permeability: from bench to bedside with caution.
Academic Article	Intracranial cavernous angioma: a practical review of clinical and biological aspects.
Academic Article	Unfolding knowledge on cerebral cavernous malformations.
Academic Article	Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM pathogenesis.
Academic Article	The cerebral cavernous malformation disease causing gene KRIT1 participates in intestinal epithelial barrier maintenance and regulation.
Academic Article	Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations.
Academic Article	Phenotypic characterization of murine models of cerebral cavernous malformations.
Academic Article	Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice.
Academic Article	Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.
Academic Article	A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis.
Academic Article	A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
Academic Article	Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.
Academic Article	Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease.
Concept	KRIT1 Protein
Academic Article	Single-nucleus DNA sequencing reveals hidden somatic loss-of-heterozygosity in Cerebral Cavernous Malformations.

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KRIT1 Protein