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Biallelic somatic and germ line CCM1 truncating mutations in a cerebral cavernous malformation lesion.
Mutational analysis of 206 families with cavernous malformations.
Spectrum of genotype and clinical manifestations in cerebral cavernous malformations.
Advanced magnetic resonance imaging of cerebral cavernous malformations: part II. Imaging of lesions in murine models.
Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.
A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
Cerebral cavernous malformations: somatic mutations in vascular endothelial cells.
Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease.
Different spectra of genomic deletions within the CCM genes between Italian and American CCM patient cohorts.
Cerebral cavernous malformations as a disease of vascular permeability: from bench to bedside with caution.
Intracranial cavernous angioma: a practical review of clinical and biological aspects.
Unfolding knowledge on cerebral cavernous malformations.
Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM pathogenesis.
ß1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations.
Microtubule Associated Proteins