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NIH 3T3 Cells
P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype.
P311 binds to the latency associated protein and downregulates the expression of TGF-beta1 and TGF-beta2.
P311-induced myofibroblasts exhibit ameboid-like migration through RalA activation.
Effects of the SANT domain of tension-induced/inhibited proteins (TIPs), novel partners of the histone acetyltransferase p300, on p300 activity and TIP-6-induced adipogenesis.
Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor ß1-3 (TGF-ß1-3).