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Rhodes, Christopher
One or more keywords matched the following items that are connected to Rhodes, Christopher
Item TypeName
Concept Glucagon-Like Peptides
Concept Intercellular Signaling Peptides and Proteins
Concept Natriuretic Peptides
Concept Antimicrobial Cationic Peptides
Concept Intracellular Signaling Peptides and Proteins
Concept Peptides
Academic Article Preferential cleavage of des-31,32-proinsulin over intact proinsulin by the insulin secretory granule type II endopeptidase. Implication of a favored route for prohormone processing.
Academic Article A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth.
Academic Article Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
Academic Article Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells.
Academic Article Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells.
Academic Article Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport.
Academic Article Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B.
Academic Article Type 2 diabetes-a matter of beta-cell life and death?
Academic Article Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells.
Academic Article Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation.
Academic Article Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt?
Academic Article Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression.
Academic Article Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level.
Academic Article The inhibition of proinsulin-processing endopeptidase activities by active-site-directed peptides.
Academic Article Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance.
Academic Article The intracellular handling of insulin-related peptides in isolated pancreatic islets. Evidence for differential rates of degradation of insulin and C-peptide.
Academic Article Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
Academic Article IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells.
Academic Article Glucagon-like peptide-1 prevents beta cell glucolipotoxicity.
Academic Article Rab3A effector domain peptides induce insulin exocytosis via a specific interaction with a cytosolic protein doublet.
Academic Article Direct innervation and modulation of orexin neurons by lateral hypothalamic LepRb neurons.
Academic Article Ca(2+)-regulated serine protease associated with the nuclear scaffold.
Academic Article Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights.
Academic Article Intracoronary endothelin induces myocardial ischemia by small vessel constriction in the dog.
Academic Article Pulmonary hypertension: biomarkers.
Academic Article The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti.
Academic Article Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis.
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