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Fluorescence Resonance Energy Transfer
A physical model of potassium channel activation: from energy landscape to gating kinetics.
A hybrid approach to measuring electrical activity in genetically specified neurons.
Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer.
Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement.
The action potential: from voltage-gated conductances to molecular structures.
In vivo measurement of intramolecular distances using genetically encoded reporters.
Nano-positioning system for structural analysis of functional homomeric proteins in multiple conformations.
Ouabain binding site in a functioning Na+/K+ ATPase.
Probing a-3(10) transitions in a voltage-sensing S4 helix.
A structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway.
?1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel.
Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET.
Determination of the Stoichiometry between a- and ?1 Subunits of the BK Channel Using LRET.
LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b.
ISS ChronosBH Fluorescence Lifetime Spectrometer
Surface Plasmon-coupled Fluorescence Microscope to Study Ion Channel Dynamics
ELECTROPHYSIOLOGICAL STUDIES OF VOLTAGE GATED CHANNELS