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The University of Chicago

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Lin, Hening

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Item Type	Name
Concept	Hydrolysis
Grant	High-throughput assays for the development of SIRT5-specific inhibitors
Academic Article	A fluorogenic assay for screening Sirt6 modulators.
Academic Article	Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase.
Academic Article	HDAC8 Catalyzes the Hydrolysis of Long Chain Fatty Acyl Lysine.
Academic Article	Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine.
Academic Article	Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.
Academic Article	SIRT6 regulates TNF-a secretion through hydrolysis of long-chain fatty acyl lysine.

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Hydrolysis