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Fluorescence Resonance Energy Transfer
The ribosome uses cooperative conformational changes to maximize and regulate the efficiency of translation.
Conducting Multiple Imaging Modes with One Fluorescence Microscope.
A highly purified, fluorescently labeled in vitro translation system for single-molecule studies of protein synthesis.
Learning rates and states from biophysical time series: a Bayesian approach to model selection and single-molecule FRET data.
Coupling of ribosomal L1 stalk and tRNA dynamics during translation elongation.
Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis.
A frameshifting stimulatory stem loop destabilizes the hybrid state and impedes ribosomal translocation.
Graphical models for inferring single molecule dynamics.
Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation.
Watching DNA breath one molecule at a time.
Transfer RNA-mediated regulation of ribosome dynamics during protein synthesis.
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices.