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One or more keywords matched the following properties of Novembre, John
keywords Population Genetics
overview The Novembre research group uses computational tools to study genetic diversity in natural populations. Our goal is to develop widely used statistical methods for intelligently extracting information from large-scale genomic data with the aim to improve understanding of: (1) basic genomic biology, (2) the biology of heritable disease traits, (3) the genetic basis of evolutionary processes, and (4) the history and evolution of various species, especially humans. From a disciplinary perspective, most of the ideas we use are from theoretical population genetics, statistical genetics, and computational statistics. Much of our work is invigorated by addressing data from emerging genotyping and sequencing technologies applied to large or particularly interesting population samples.
One or more keywords matched the following items that are connected to Novembre, John
Item TypeName
Concept Genetics, Population
Academic Article Perspectives on human population structure at the cusp of the sequencing era.
Academic Article Genes mirror geography within Europe.
Academic Article Fast model-based estimation of ancestry in unrelated individuals.
Academic Article The geographic spread of the CCR5 Delta32 HIV-resistance allele.
Academic Article Principal component analysis under population genetic models of range expansion and admixture.
Academic Article Characterizing bias in population genetic inferences from low-coverage sequencing data.
Academic Article Novel statistical methods for integrating genetic and stable isotope data to infer individual-level migratory connectivity.
Academic Article forqs: forward-in-time simulation of recombination, quantitative traits and selection.
Academic Article Visualizing spatial population structure with estimated effective migration surfaces.
Academic Article Demographically-Based Evaluation of Genomic Regions under Selection in Domestic Dogs.
Academic Article Conflation of Short Identity-by-Descent Segments Bias Their Inferred Length Distribution.
Academic Article Recent advances in the study of fine-scale population structure in humans.
Academic Article A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans.
Academic Article Population- and individual-specific regulatory variation in Sardinia.
Academic Article Genomic history of the Sardinian population.
Academic Article A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau.
Academic Article The genetic prehistory of the Andean highlands 7000 years BP though European contact.
Academic Article Estimating recent migration and population-size surfaces.
Academic Article Exploring Population Structure with Admixture Models and Principal Component Analysis.
Academic Article Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia.
Academic Article A variant-centric perspective on geographic patterns of human allele frequency variation.
Academic Article Fast and flexible estimation of effective migration surfaces.
Academic Article Properties of 2-locus genealogies and linkage disequilibrium in temporally structured samples.
Grant Haplotype-based analysis methods for population genomics
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  • Genetics Population