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Novembre, John
One or more keywords matched the following properties of Novembre, John
PropertyValue
keywords Human Genetics
overview The Novembre research group uses computational tools to study genetic diversity in natural populations. Our goal is to develop widely used statistical methods for intelligently extracting information from large-scale genomic data with the aim to improve understanding of: (1) basic genomic biology, (2) the biology of heritable disease traits, (3) the genetic basis of evolutionary processes, and (4) the history and evolution of various species, especially humans. From a disciplinary perspective, most of the ideas we use are from theoretical population genetics, statistical genetics, and computational statistics. Much of our work is invigorated by addressing data from emerging genotyping and sequencing technologies applied to large or particularly interesting population samples.
One or more keywords matched the following items that are connected to Novembre, John
Item TypeName
Concept Humans
Concept Genome, Human
Concept Chromosomes, Human, X
Concept Chromosomes, Human, Y
Academic Article Spatial patterns of variation due to natural selection in humans.
Academic Article Recombination rates in admixed individuals identified by ancestry-based inference.
Academic Article Perspectives on human population structure at the cusp of the sequencing era.
Academic Article Genes mirror geography within Europe.
Academic Article Inferring genetic ancestry: opportunities, challenges, and implications.
Academic Article Fast model-based estimation of ancestry in unrelated individuals.
Academic Article The geographic spread of the CCR5 Delta32 HIV-resistance allele.
Academic Article An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people.
Academic Article Principal component analysis under population genetic models of range expansion and admixture.
Academic Article Maximum likelihood estimation of frequencies of known haplotypes from pooled sequence data.
Academic Article Characterizing bias in population genetic inferences from low-coverage sequencing data.
Academic Article forqs: forward-in-time simulation of recombination, quantitative traits and selection.
Academic Article Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European.
Academic Article Height-reducing variants and selection for short stature in Sardinia.
Academic Article Visualizing spatial population structure with estimated effective migration surfaces.
Academic Article Conflation of Short Identity-by-Descent Segments Bias Their Inferred Length Distribution.
Academic Article Visualizing the geography of genetic variants.
Academic Article Recent advances in the study of fine-scale population structure in humans.
Academic Article A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans.
Academic Article Population- and individual-specific regulatory variation in Sardinia.
Academic Article Overexpression of the Cytokine BAFF and Autoimmunity Risk.
Academic Article Genomic history of the Sardinian population.
Academic Article Using pseudoalignment and base quality to accurately quantify microbial community composition.
Academic Article Estimating Time to the Common Ancestor for a Beneficial Allele.
Academic Article A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau.
Academic Article Inference and visualization of DNA damage patterns using a grade of membership model.
Academic Article The genetic prehistory of the Andean highlands 7000 years BP though European contact.
Academic Article Correction: A longitudinal cline characterizes the genetic structure of human populations in the Tibetan plateau.
Academic Article The first horse herders and the impact of early Bronze Age steppe expansions into Asia.
Academic Article Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal.
Academic Article Estimating recent migration and population-size surfaces.
Academic Article Genetic Landscapes Reveal How Human Genetic Diversity Aligns with Geography.
Academic Article Exploring Population Structure with Admixture Models and Principal Component Analysis.
Academic Article Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia.
Academic Article A variant-centric perspective on geographic patterns of human allele frequency variation.
Academic Article Public attitudes toward genetic risk scoring in medicine and beyond.
Academic Article Parental relatedness through time revealed by runs of homozygosity in ancient DNA.
Academic Article Haplotype-based inference of the distribution of fitness effects.
Academic Article Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors.
Academic Article Properties of 2-locus genealogies and linkage disequilibrium in temporally structured samples.
Academic Article The background and legacy of Lewontin's apportionment of human genetic diversity.
Academic Article Addressing the challenges of polygenic scores in human genetic research.
Academic Article Modeling the spatiotemporal spread of beneficial alleles using ancient genomes.
Academic Article Population genetic models for the spatial spread of adaptive variants: A review in light of SARS-CoV-2 evolution.
Concept Human Migration
Grant Extending Tools for Visualization of Geographic Structure in Population Genomic Data
Grant Tools for Visualization of Geographic Structure in Population Genomic Data
Grant Population Genetic Consequences of Recent Explosive Population Growth in Humans
Grant Haplotype-based analysis methods for population genomics
Academic Article A rarefaction approach for measuring population differences in rare and common variation.
Academic Article Mexican Biobank advances population and medical genomics of diverse ancestries.
Search Criteria
  • Humans