 Pain Insensitivity, Congenital
"Pain Insensitivity, Congenital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome characterized by indifference to PAIN despite the ability to distinguish noxious from nonnoxious stimuli. Absent corneal reflexes and INTELLECTUAL DISABILITY may be associated. Familial forms with autosomal recessive and autosomal dominant patterns of inheritance have been described. (Adams et al., Principles of Neurology, 6th ed, p1343)
| Descriptor ID |
D000699
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| MeSH Number(s) |
C10.668.829.700 C16.320.775
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| Concept/Terms |
Pain Insensitivity, Congenital- Pain Insensitivity, Congenital
- Insensitivity, Congenital Pain
- Congenital Pain Insensitivity
- Congenital Analgesia
- Congenital Indifference to Pain
- Pain Indifference, Congenital
- Congenital Pain Indifference
- Congenital Pain Indifferences
- Analgesia, Congenital
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Below are MeSH descriptors whose meaning is more general than "Pain Insensitivity, Congenital".
Below are MeSH descriptors whose meaning is more specific than "Pain Insensitivity, Congenital".
This graph shows the total number of publications written about "Pain Insensitivity, Congenital" by people in this website by year, and whether "Pain Insensitivity, Congenital" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pain Insensitivity, Congenital" by people in Profiles.
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Moraes BC, Ribeiro-Filho HV, Rold?o AP, Toniolo EF, Carretero GPB, Sgro GG, Batista FAH, Berardi DE, Oliveira VRS, Tomasin R, Vieceli FM, Pramio DT, Cardoso AB, Figueira ACM, Farah SC, Devi LA, Dale CS, de Oliveira PSL, Schechtman D. Structural analysis of TrkA mutations in patients with congenital insensitivity to pain reveals PLC? as an analgesic drug target. Sci Signal. 2022 04 26; 15(731):eabm6046.
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Pavone L, Huttenlocher P, Siciliano L, Micali G, Rizzo R, Anastasi M, Maimone D, Woolmann R. Two brothers with a variant of hereditary sensory neuropathy. Neuropediatrics. 1992 Apr; 23(2):92-5.
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