The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance.

Descriptor ID	D009386
MeSH Number(s)	C04.700 C16.320.700
Concept/Terms	Neoplastic Syndromes, Hereditary Neoplastic Syndromes, Hereditary Hereditary Neoplastic Syndromes Hereditary Neoplastic Syndrome Neoplastic Syndrome, Hereditary Syndrome, Hereditary Neoplastic Syndromes, Hereditary Neoplastic Hereditary Cancer Syndromes Cancer Syndrome, Hereditary Hereditary Cancer Syndrome Syndrome, Hereditary Cancer Syndromes, Hereditary Cancer Cancer Syndromes, Hereditary

Below are MeSH descriptors whose meaning is more general than "Neoplastic Syndromes, Hereditary".

Below are MeSH descriptors whose meaning is related to "Neoplastic Syndromes, Hereditary".

Below are MeSH descriptors whose meaning is more specific than "Neoplastic Syndromes, Hereditary".