 Antigen-Presenting Cells
"Antigen-Presenting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.
| Descriptor ID |
D000938
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| MeSH Number(s) |
A11.066 A15.382.066
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| Concept/Terms |
Antigen-Presenting Cells- Antigen-Presenting Cells
- Antigen Presenting Cells
- Antigen-Presenting Cell
- Cell, Antigen-Presenting
- Cells, Antigen-Presenting
- Accessory Cells, Immunologic
- Immunologic Accessory Cells
- Cells, Immunologic Accessory
- Immunologic Accessory Cell
- Accessory Cell, Immunologic
- Cell, Immunologic Accessory
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Below are MeSH descriptors whose meaning is more general than "Antigen-Presenting Cells".
Below are MeSH descriptors whose meaning is more specific than "Antigen-Presenting Cells".
This graph shows the total number of publications written about "Antigen-Presenting Cells" by people in this website by year, and whether "Antigen-Presenting Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1986 | 0 | 1 | 1 | | 1988 | 1 | 0 | 1 | | 1989 | 2 | 2 | 4 | | 1990 | 1 | 1 | 2 | | 1991 | 1 | 3 | 4 | | 1992 | 1 | 0 | 1 | | 1993 | 3 | 3 | 6 | | 1994 | 1 | 3 | 4 | | 1995 | 1 | 1 | 2 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 1 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 0 | 4 | 4 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 3 | 4 | | 2002 | 1 | 3 | 4 | | 2003 | 0 | 4 | 4 | | 2004 | 2 | 3 | 5 | | 2005 | 0 | 2 | 2 | | 2006 | 2 | 0 | 2 | | 2007 | 1 | 3 | 4 | | 2008 | 0 | 2 | 2 | | 2009 | 1 | 2 | 3 | | 2010 | 1 | 3 | 4 | | 2011 | 2 | 1 | 3 | | 2012 | 3 | 2 | 5 | | 2013 | 1 | 2 | 3 | | 2014 | 1 | 5 | 6 | | 2015 | 2 | 2 | 4 | | 2016 | 2 | 7 | 9 | | 2017 | 1 | 0 | 1 | | 2019 | 0 | 2 | 2 | | 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Antigen-Presenting Cells" by people in Profiles.
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Chong AS. B cells as antigen-presenting cells in transplantation rejection and tolerance. Cell Immunol. 2020 03; 349:104061.
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Lei YM, Sepulveda M, Chen L, Wang Y, Pirozzolo I, Theriault B, Chong AS, Belkaid Y, Alegre ML. Skin-restricted commensal colonization accelerates skin graft rejection. JCI Insight. 2019 07 16; 5.
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Guram K, Kim SS, Wu V, Sanders PD, Patel S, Schoenberger SP, Cohen EEW, Chen SY, Sharabi AB. A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy. Front Immunol. 2019; 10:491.
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Curran EK, Godfrey J, Kline J. Mechanisms of Immune Tolerance in Leukemia and Lymphoma. Trends Immunol. 2017 07; 38(7):513-525.
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Sweis RF, Galsky MD. Emerging role of immunotherapy in urothelial carcinoma-Immunobiology/biomarkers. Urol Oncol. 2016 12; 34(12):556-565.
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Perera J, Zheng Z, Li S, Gudjonson H, Kalinina O, Benichou JIC, Block KE, Louzoun Y, Yin D, Chong AS, Dinner AR, Weigert M, Huang H. Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance. Cell Rep. 2016 10 04; 17(2):387-398.
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Corrales L, McWhirter SM, Dubensky TW, Gajewski TF. The host STING pathway at the interface of cancer and immunity. J Clin Invest. 2016 07 01; 126(7):2404-11.
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Lei YM, Chen L, Wang Y, Stefka AT, Molinero LL, Theriault B, Aquino-Michaels K, Sivan AS, Nagler CR, Gajewski TF, Chong AS, Bartman C, Alegre ML. The composition of the microbiota modulates allograft rejection. J Clin Invest. 2016 07 01; 126(7):2736-44.
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Curran E, Chen X, Corrales L, Kline DE, Dubensky TW, Duttagupta P, Kortylewski M, Kline J. STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia. Cell Rep. 2016 06 14; 15(11):2357-66.
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Miller ML, Chen J, Daniels MD, McKeague MG, Wang Y, Yin D, Vu V, Chong AS, Alegre ML. Adoptive Transfer of Tracer-Alloreactive CD4+ T Cell Receptor Transgenic T Cells Alters the Endogenous Immune Response to an Allograft. Am J Transplant. 2016 10; 16(10):2842-2853.
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