 Antigen-Presenting Cells
"Antigen-Presenting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.
| Descriptor ID |
D000938
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| MeSH Number(s) |
A11.066 A15.382.066
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| Concept/Terms |
Antigen-Presenting Cells- Antigen-Presenting Cells
- Antigen Presenting Cells
- Antigen-Presenting Cell
- Cell, Antigen-Presenting
- Cells, Antigen-Presenting
- Accessory Cells, Immunologic
- Immunologic Accessory Cells
- Cells, Immunologic Accessory
- Immunologic Accessory Cell
- Accessory Cell, Immunologic
- Cell, Immunologic Accessory
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Below are MeSH descriptors whose meaning is more general than "Antigen-Presenting Cells".
Below are MeSH descriptors whose meaning is more specific than "Antigen-Presenting Cells".
This graph shows the total number of publications written about "Antigen-Presenting Cells" by people in this website by year, and whether "Antigen-Presenting Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 0 | 1 | 1 | | 1988 | 1 | 0 | 1 | | 1989 | 2 | 2 | 4 | | 1990 | 1 | 1 | 2 | | 1991 | 1 | 3 | 4 | | 1992 | 1 | 0 | 1 | | 1993 | 3 | 3 | 6 | | 1994 | 1 | 3 | 4 | | 1995 | 1 | 1 | 2 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 1 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 0 | 4 | 4 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 3 | 4 | | 2002 | 1 | 3 | 4 | | 2003 | 0 | 4 | 4 | | 2004 | 2 | 3 | 5 | | 2005 | 0 | 2 | 2 | | 2006 | 2 | 0 | 2 | | 2007 | 1 | 3 | 4 | | 2008 | 0 | 2 | 2 | | 2009 | 1 | 2 | 3 | | 2010 | 1 | 4 | 5 | | 2011 | 2 | 1 | 3 | | 2012 | 3 | 3 | 6 | | 2013 | 1 | 4 | 5 | | 2014 | 1 | 5 | 6 | | 2015 | 2 | 2 | 4 | | 2016 | 2 | 8 | 10 | | 2017 | 1 | 0 | 1 | | 2019 | 0 | 2 | 2 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 5 | 5 |
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Below are the most recent publications written about "Antigen-Presenting Cells" by people in Profiles.
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Guo N, Ni K, Luo T, Lan G, Arina A, Xu Z, Mao J, Weichselbaum RR, Spiotto M, Lin W. Reprogramming of Neutrophils as Non-canonical Antigen Presenting Cells by Radiotherapy-Radiodynamic Therapy to Facilitate Immune-Mediated Tumor Regression. ACS Nano. 2021 11 23; 15(11):17515-17527.
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Maulloo CD, Cao S, Watkins EA, Raczy MM, Solanki AS, Nguyen M, Reda JW, Shim HN, Wilson DS, Swartz MA, Hubbell JA. Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance. Front Immunol. 2021; 12:714842.
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Kim SS, Sumner WA, Miyauchi S, Cohen EEW, Califano JA, Sharabi AB. Role of B Cells in Responses to Checkpoint Blockade Immunotherapy and Overall Survival of Cancer Patients. Clin Cancer Res. 2021 11 15; 27(22):6075-6082.
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Weiss AM, Ajit J, Albin TJ, Kapoor N, Maroju S, Berges A, Pill L, Fairman J, Esser-Kahn AP. Site-specific antigen-adjuvant conjugation using cell-free protein synthesis enhances antigen presentation and CD8+ T-cell response. Sci Rep. 2021 03 18; 11(1):6267.
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Yuba E, Budina E, Katsumata K, Ishihara A, Mansurov A, Alpar AT, Watkins EA, Hosseinchi P, Reda JW, Lauterbach AL, Nguyen M, Solanki A, Kageyama T, Swartz MA, Ishihara J, Hubbell JA. Suppression of Rheumatoid Arthritis by Enhanced Lymph Node Trafficking of Engineered Interleukin-10 in Murine Models. Arthritis Rheumatol. 2021 05; 73(5):769-778.
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Didonna A, Damotte V, Shams H, Matsunaga A, Caillier SJ, Dandekar R, Misra MK, Mofrad MRK, Oksenberg JR, Hollenbach JA. A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain. Immunology. 2021 02; 162(2):194-207.
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Chong AS. B cells as antigen-presenting cells in transplantation rejection and tolerance. Cell Immunol. 2020 03; 349:104061.
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Savage PA, Klawon DEJ, Miller CH. Regulatory T Cell Development. Annu Rev Immunol. 2020 04 26; 38:421-453.
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Lei YM, Sepulveda M, Chen L, Wang Y, Pirozzolo I, Theriault B, Chong AS, Belkaid Y, Alegre ML. Skin-restricted commensal colonization accelerates skin graft rejection. JCI Insight. 2019 07 16; 5.
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Guram K, Kim SS, Wu V, Sanders PD, Patel S, Schoenberger SP, Cohen EEW, Chen SY, Sharabi AB. A Threshold Model for T-Cell Activation in the Era of Checkpoint Blockade Immunotherapy. Front Immunol. 2019; 10:491.
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