"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
| Descriptor ID |
D007108
|
| MeSH Number(s) |
G12.535.425
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 2 | 4 |
| 1997 | 5 | 6 | 11 |
| 1998 | 0 | 2 | 2 |
| 1999 | 4 | 1 | 5 |
| 2000 | 6 | 1 | 7 |
| 2001 | 6 | 4 | 10 |
| 2002 | 3 | 1 | 4 |
| 2003 | 5 | 3 | 8 |
| 2004 | 3 | 3 | 6 |
| 2005 | 4 | 4 | 8 |
| 2006 | 11 | 4 | 15 |
| 2007 | 3 | 3 | 6 |
| 2008 | 3 | 3 | 6 |
| 2009 | 1 | 6 | 7 |
| 2010 | 4 | 4 | 8 |
| 2011 | 12 | 5 | 17 |
| 2012 | 8 | 4 | 12 |
| 2013 | 4 | 7 | 11 |
| 2014 | 7 | 7 | 14 |
| 2015 | 9 | 3 | 12 |
| 2016 | 7 | 3 | 10 |
| 2017 | 9 | 5 | 14 |
| 2018 | 1 | 5 | 6 |
| 2019 | 5 | 4 | 9 |
| 2020 | 3 | 3 | 6 |
| 2021 | 4 | 6 | 10 |
| 2022 | 3 | 10 | 13 |
| 2023 | 2 | 3 | 5 |
| 2024 | 2 | 0 | 2 |
| 2025 | 10 | 2 | 12 |
| 2026 | 3 | 2 | 5 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Integrated Single-Cell Profiling Reveals Dichotomous NK Cell Populations Associated with Immunosuppression in Solid Tumors. Cancer Immunol Res. 2026 Jun 02; 14(6):1008-1021.
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Tissue-specific tolerance mechanisms and lymph node co-drainage shape T cell immunity in the upper digestive system and pancreatic cancer progression. Cell Rep. 2026 May 26; 45(5):117324.
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Microbial Therapeutics for the Prevention and Treatment of Food Allergy. J Allergy Clin Immunol Pract. 2026 04; 14(4):780-785.
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Differential disease tolerance mediates sex-biased illness severity in sepsis. Proc Natl Acad Sci U S A. 2026 Mar 03; 123(9):e2522764123.
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Transcription factor Etv3 controls the tolerogenic function of dendritic cells. Science. 2026 Feb 12; 391(6786):eads1246.
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Neuropeptide adrenomedullin remodels stemness and macrophage dynamics in glioblastoma. Cell Rep. 2025 10 28; 44(10):116342.
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Thymic epithelial cells amplify epigenetic noise to promote immune tolerance. Nature. 2025 10; 646(8085):724-733.
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Hyporesponsive fetus-specific T cell responses in multiparous human pregnancy. Front Immunol. 2025; 16:1634430.
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Cell-intrinsic CD4 T cell tolerance: a new frontier in therapy? Trends Immunol. 2025 09; 46(9):624-634.
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Radiation-induced amphiregulin drives tumour metastasis. Nature. 2025 07; 643(8072):810-819.