"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
| Descriptor ID |
D007108
|
| MeSH Number(s) |
G12.535.425
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 2 | 4 |
| 1997 | 5 | 6 | 11 |
| 1998 | 0 | 2 | 2 |
| 1999 | 4 | 2 | 6 |
| 2000 | 6 | 1 | 7 |
| 2001 | 6 | 4 | 10 |
| 2002 | 3 | 1 | 4 |
| 2003 | 5 | 3 | 8 |
| 2004 | 3 | 3 | 6 |
| 2005 | 4 | 4 | 8 |
| 2006 | 10 | 4 | 14 |
| 2007 | 3 | 3 | 6 |
| 2008 | 3 | 3 | 6 |
| 2009 | 1 | 6 | 7 |
| 2010 | 5 | 4 | 9 |
| 2011 | 12 | 5 | 17 |
| 2012 | 8 | 4 | 12 |
| 2013 | 4 | 7 | 11 |
| 2014 | 7 | 7 | 14 |
| 2015 | 9 | 3 | 12 |
| 2016 | 7 | 3 | 10 |
| 2017 | 10 | 5 | 15 |
| 2018 | 1 | 5 | 6 |
| 2019 | 5 | 4 | 9 |
| 2020 | 3 | 3 | 6 |
| 2021 | 4 | 6 | 10 |
| 2022 | 3 | 10 | 13 |
| 2023 | 2 | 3 | 5 |
| 2024 | 2 | 0 | 2 |
| 2025 | 6 | 2 | 8 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Transcription factor Etv3 controls the tolerogenic function of dendritic cells. Science. 2026 Feb 12; 391(6786):eads1246.
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Thymic epithelial cells amplify epigenetic noise to promote immune tolerance. Nature. 2025 Oct; 646(8085):724-733.
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Cell-intrinsic CD4 T cell tolerance: a new frontier in therapy? Trends Immunol. 2025 Sep; 46(9):624-634.
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Radiation-induced amphiregulin drives tumour metastasis. Nature. 2025 Jul; 643(8072):810-819.
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A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection. Cell. 2025 Jun 12; 188(12):3135-3151.e22.
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Liver-targeted allergen immunotherapy rapidly and safely induces antigen-specific tolerance to treat allergic airway disease in mice. Sci Transl Med. 2025 Apr 16; 17(794):eadl0406.
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CAR Treg synergy with anti-CD154 promotes infectious tolerance and dictates allogeneic heart transplant acceptance. JCI Insight. 2025 Apr 08; 10(7).
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Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection. Science. 2025 Mar 21; 387(6740):eadk3248.
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ß-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus. Nat Immunol. 2025 Feb; 26(2):174-187.
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The role of intestinal bacteria in promoting tolerance to food. Curr Opin Immunol. 2024 Dec; 91:102492.