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Amiloride

"Amiloride" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)


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This graph shows the total number of publications written about "Amiloride" by people in this website by year, and whether "Amiloride" was a major or minor topic of these publications.
Bar chart showing 37 publications over 26 distinct years, with a maximum of 3 publications in 1983 and 1990 and 1991
To see the data from this visualization as text, click here.