Sodium-Hydrogen Exchangers
"Sodium-Hydrogen Exchangers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of plasma membrane exchange glycoprotein antiporters that transport sodium ions and protons across lipid bilayers. They have critical functions in intracellular pH regulation, cell volume regulation, and cellular response to many different hormones and mitogens.
| Descriptor ID |
D017923
|
| MeSH Number(s) |
D12.776.157.530.450.162.775 D12.776.157.530.937.703 D12.776.543.550.190.775 D12.776.543.585.450.162.775 D12.776.543.585.937.828
|
| Concept/Terms |
Sodium-Hydrogen Exchangers- Sodium-Hydrogen Exchangers
- Exchangers, Sodium-Hydrogen
- Sodium Hydrogen Exchangers
- Na(+)-H(+)-Antiporter
- Na(+)-H(+)-Exchangers
- Sodium-Proton Antiporters
- Antiporters, Sodium-Proton
- Sodium Proton Antiporters
- Solute Carrier 9 Proteins
- SLC9 Na(+)-H(+) Exchangers
- SLC9 Protein Family
- Protein Family, SLC9
- SLC9-NHE Protein Family
- Protein Family, SLC9-NHE
- SLC9 NHE Protein Family
- SLC9 Proteins
- Solute Carrier 9 Protein Family
- Sodium-Hydrogen Antiporter
- Antiporter, Sodium-Hydrogen
- Sodium Hydrogen Antiporter
- Na(+)-H(+)-Exchanger
- Sodium-Hydrogen Exchanger
- Exchanger, Sodium-Hydrogen
- Sodium Hydrogen Exchanger
- Sodium-Proton Antiporter
- Antiporter, Sodium-Proton
- Sodium Proton Antiporter
- Sodium-Hydrogen Antiporters
- Antiporters, Sodium-Hydrogen
- Sodium Hydrogen Antiporters
- Na(+)-H(+)-Antiporters
|
Below are MeSH descriptors whose meaning is more general than "Sodium-Hydrogen Exchangers".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Hydrogen Exchangers".
This graph shows the total number of publications written about "Sodium-Hydrogen Exchangers" by people in this website by year, and whether "Sodium-Hydrogen Exchangers" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 5 | 0 | 5 |
| 1997 | 3 | 0 | 3 |
| 1998 | 2 | 0 | 2 |
| 1999 | 4 | 0 | 4 |
| 2000 | 2 | 1 | 3 |
| 2001 | 2 | 0 | 2 |
| 2002 | 3 | 0 | 3 |
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 3 | 2 | 5 |
| 2009 | 3 | 0 | 3 |
| 2010 | 2 | 1 | 3 |
| 2013 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sodium-Hydrogen Exchangers" by people in Profiles.
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Tenapanor: A Phosphate Absorption Inhibitor for the Management of Hyperphosphatemia in Patients With Kidney Failure. J Ren Nutr. 2025 Jan; 35(1):25-34.
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Evidence for a role of PDZ domain-containing proteins to mediate hypophosphatemia in calcium stone formers. Nephrol Dial Transplant. 2018 05 01; 33(5):759-770.
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Human and mouse tissue-engineered small intestine both demonstrate digestive and absorptive function. Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15; 308(8):G664-77.
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Analysis of Ca2+ signaling motifs that regulate proton signaling through the Na+/H+ exchanger NHX-7 during a rhythmic behavior in Caenorhabditis elegans. J Biol Chem. 2013 Feb 22; 288(8):5886-95.
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Comparison of the pathology of interstitial plaque in human ICSF stone patients to NHERF-1 and THP-null mice. Urol Res. 2010 Dec; 38(6):439-52.
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D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process. Gastroenterology. 2011 Feb; 140(2):560-71.
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Preserved Na(+)/H(+) exchanger isoform 3 expression and localization, but decreased NHE3 function indicate regulatory sodium transport defect in ulcerative colitis. Inflamm Bowel Dis. 2010 Jul; 16(7):1149-61.
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Sip1, the Drosophila orthologue of EBP50/NHERF1, functions with the sterile 20 family kinase Slik to regulate Moesin activity. J Cell Sci. 2010 Apr 01; 123(Pt 7):1099-107.
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Cyclic AMP-mediated endocytosis of intestinal epithelial NHE3 requires binding to synaptotagmin 1. Am J Physiol Gastrointest Liver Physiol. 2010 Feb; 298(2):G203-11.
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Alpha2-adrenergic receptors attenuate secretagogue-induced endocytosis and promote exocytosis of intestinal NHE2 and NHE3. J Pharmacol Exp Ther. 2009 Sep; 330(3):818-25.