Acetyl-CoA C-Acetyltransferase
"Acetyl-CoA C-Acetyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of acetoacetyl-CoA from two molecules of ACETYL COA. Some enzymes called thiolase or thiolase-I have referred to this activity or to the activity of ACETYL-COA C-ACYLTRANSFERASE.
Descriptor ID |
D000101
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MeSH Number(s) |
D08.811.913.050.134.025
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Concept/Terms |
Acetyl-CoA C-Acetyltransferase- Acetyl-CoA C-Acetyltransferase
- Acetyl CoA C Acetyltransferase
- C-Acetyltransferase, Acetyl-CoA
- Acetyl Coenzyme A Acetyltransferase
- Acetoacetyl CoA Thiolase
- CoA Thiolase, Acetoacetyl
- Thiolase, Acetoacetyl CoA
- Acetyl-CoA Acetyltransferase
- Acetyl CoA Acetyltransferase
- Acetyltransferase, Acetyl-CoA
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Below are MeSH descriptors whose meaning is more general than "Acetyl-CoA C-Acetyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Acetyl-CoA C-Acetyltransferase".
This graph shows the total number of publications written about "Acetyl-CoA C-Acetyltransferase" by people in this website by year, and whether "Acetyl-CoA C-Acetyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 | 2014 | 2 | 0 | 2 | 2016 | 1 | 0 | 1 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Acetyl-CoA C-Acetyltransferase" by people in Profiles.
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Chen D, Xia S, Zhang R, Li Y, Famulare CA, Fan H, Wu R, Wang M, Zhu AC, Elf SE, Su R, Dong L, Arellano M, Blum WG, Mao H, Lonial S, Stock W, Odenike O, Le Beau M, Boggon TJ, He C, Chen J, Gao X, Levine RL, Chen J. Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells. Mol Cell. 2021 09 16; 81(18):3833-3847.e11.
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Fan J, Lin R, Xia S, Chen D, Elf SE, Liu S, Pan Y, Xu H, Qian Z, Wang M, Shan C, Zhou L, Lei QY, Li Y, Mao H, Lee BH, Sudderth J, DeBerardinis RJ, Zhang G, Owonikoko T, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Kang S, Doetsch PW, Lonial S, Boggon TJ, Curran WJ, Chen J. Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth. Mol Cell. 2016 12 01; 64(5):859-874.
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Shan C, Elf S, Ji Q, Kang HB, Zhou L, Hitosugi T, Jin L, Lin R, Zhang L, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J. Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth. Mol Cell. 2014 Aug 21; 55(4):552-65.
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Fan J, Shan C, Kang HB, Elf S, Xie J, Tucker M, Gu TL, Aguiar M, Lonning S, Chen H, Mohammadi M, Britton LM, Garcia BA, Aleckovic M, Kang Y, Kaluz S, Devi N, Van Meir EG, Hitosugi T, Seo JH, Lonial S, Gaddh M, Arellano M, Khoury HJ, Khuri FR, Boggon TJ, Kang S, Chen J. Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Mol Cell. 2014 Feb 20; 53(4):534-48.
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Yang LM, Lamppa G. Identification of a chloroplast coenzyme A-binding protein related to the peroxisomal thiolases. Plant Physiol. 1996 Dec; 112(4):1641-7.
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