Proto-Oncogene Proteins B-raf
"Proto-Oncogene Proteins B-raf" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.
| Descriptor ID |
D048493
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| MeSH Number(s) |
D08.811.913.696.620.682.700.559.842.374 D12.644.360.400.842.374 D12.776.476.400.842.437 D12.776.624.664.700.204.200
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| Concept/Terms |
Proto-Oncogene Proteins B-raf- Proto-Oncogene Proteins B-raf
- B-raf, Proto-Oncogene Proteins
- Proteins B-raf, Proto-Oncogene
- Proto Oncogene Proteins B raf
- BRAF Kinases
- B-raf Kinases
- B raf Kinases
- Proto-Oncogene Protein B-raf
- B-raf, Proto-Oncogene Protein
- Protein B-raf, Proto-Oncogene
- Proto Oncogene Protein B raf
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins B-raf".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins B-raf".
This graph shows the total number of publications written about "Proto-Oncogene Proteins B-raf" by people in this website by year, and whether "Proto-Oncogene Proteins B-raf" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 4 | 2 | 6 |
| 2011 | 5 | 7 | 12 |
| 2012 | 6 | 4 | 10 |
| 2013 | 7 | 3 | 10 |
| 2014 | 3 | 3 | 6 |
| 2015 | 4 | 0 | 4 |
| 2016 | 1 | 1 | 2 |
| 2017 | 5 | 5 | 10 |
| 2018 | 5 | 4 | 9 |
| 2019 | 4 | 3 | 7 |
| 2020 | 4 | 6 | 10 |
| 2021 | 1 | 2 | 3 |
| 2022 | 1 | 4 | 5 |
| 2023 | 0 | 3 | 3 |
| 2024 | 2 | 2 | 4 |
| 2025 | 2 | 2 | 4 |
| 2026 | 2 | 1 | 3 |
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Below are the most recent publications written about "Proto-Oncogene Proteins B-raf" by people in Profiles.
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Prognostic and therapeutic implications of BRAF mutations in acute myeloid leukemia. Leukemia. 2026 Aug; 40(8):1688-1697.
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Real-world treatment and outcomes in hairy cell leukemia: a multicenter retrospective cohort including BRAF inhibitor therapy. Leuk Lymphoma. 2026 Aug; 67(10):2064-2072.
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Targeting Melanoma-Associated Fibroblasts to Overcome Cancer Stem Cell-Driven Drug Resistance. J Am Coll Surg. 2026 Apr 01; 242(4):761-771.
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First-line immunotherapy with or without chemotherapy versus BRAF plus MEK inhibitors in BRAFV600E-mutated metastatic non-small-cell lung cancer (FRONT-BRAF): a multicentre, retrospective cohort study. Lancet Oncol. 2025 Oct; 26(10):1357-1369.
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Revisionist history uncovers a simplified molecular-based classification of differentiated thyroid cancer. J Pathol. 2025 10; 267(2):130-141.
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Renal Tumorigenesis via RAS/RAF/MAPK Pathway Alterations Beyond Papillary Renal Neoplasm With Reverse Polarity. Am J Surg Pathol. 2025 Dec 01; 49(12):1266-1278.
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Prevalence and Clinical Impact of BRAF p.V600E Mutation in Papillary Thyroid Carcinoma. Endocr Pathol. 2025 Apr 16; 36(1):13.
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Exploring markers of immunoresponsiveness in papillary thyroid carcinoma and future treatment strategies. J Immunother Cancer. 2024 Jul 29; 12(7).
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Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma. Clin Transl Med. 2024 07; 14(7):e1773.
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Regorafenib in Patients With Solid Tumors With BRAF Alterations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study. JCO Precis Oncol. 2024 04; 8:e2300527.