 Anti-Inflammatory Agents, Non-Steroidal
"Anti-Inflammatory Agents, Non-Steroidal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or TYPE C PHOSPHOLIPASES or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)
| Descriptor ID |
D000894
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| MeSH Number(s) |
D27.505.696.663.850.014.040.500 D27.505.954.158.030 D27.505.954.329.030
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| Concept/Terms |
Anti-Inflammatory Agents, Non-Steroidal- Anti-Inflammatory Agents, Non-Steroidal
- Anti Inflammatory Agents, Non Steroidal
- Anti Inflammatory Agents, Nonsteroidal
- NSAIDs
- Antiinflammatory Agents, Non Steroidal
- Antiinflammatory Agents, Nonsteroidal
- Agents, Nonsteroidal Antiinflammatory
- Nonsteroidal Antiinflammatory Agents
- Non-Steroidal Anti-Inflammatory Agents
- Agents, Non-Steroidal Anti-Inflammatory
- Non Steroidal Anti Inflammatory Agents
- Nonsteroidal Anti-Inflammatory Agents
- Agents, Nonsteroidal Anti-Inflammatory
- Anti-Inflammatory Agents, Nonsteroidal
- Nonsteroidal Anti Inflammatory Agents
Anti-Rheumatic Agents, Non-Steroidal- Anti-Rheumatic Agents, Non-Steroidal
- Agents, Non-Steroidal Anti-Rheumatic
- Anti Rheumatic Agents, Non Steroidal
- Non-Steroidal Anti-Rheumatic Agents
- Antirheumatic Agents, Non-Steroidal
- Agents, Non-Steroidal Antirheumatic
- Antirheumatic Agents, Non Steroidal
- Non-Steroidal Antirheumatic Agents
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Below are MeSH descriptors whose meaning is more general than "Anti-Inflammatory Agents, Non-Steroidal".
Below are MeSH descriptors whose meaning is more specific than "Anti-Inflammatory Agents, Non-Steroidal".
This graph shows the total number of publications written about "Anti-Inflammatory Agents, Non-Steroidal" by people in this website by year, and whether "Anti-Inflammatory Agents, Non-Steroidal" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 1 | 0 | 1 | | 1989 | 2 | 0 | 2 | | 1990 | 1 | 0 | 1 | | 1992 | 0 | 1 | 1 | | 1994 | 0 | 2 | 2 | | 1995 | 3 | 0 | 3 | | 1996 | 2 | 1 | 3 | | 1997 | 1 | 0 | 1 | | 1998 | 4 | 0 | 4 | | 1999 | 5 | 3 | 8 | | 2000 | 4 | 4 | 8 | | 2001 | 3 | 5 | 8 | | 2002 | 2 | 4 | 6 | | 2003 | 8 | 4 | 12 | | 2004 | 4 | 5 | 9 | | 2005 | 10 | 1 | 11 | | 2006 | 2 | 7 | 9 | | 2007 | 6 | 1 | 7 | | 2008 | 8 | 3 | 11 | | 2009 | 3 | 1 | 4 | | 2010 | 3 | 1 | 4 | | 2011 | 4 | 1 | 5 | | 2012 | 10 | 3 | 13 | | 2013 | 9 | 2 | 11 | | 2014 | 7 | 4 | 11 | | 2015 | 3 | 3 | 6 | | 2016 | 5 | 3 | 8 | | 2017 | 3 | 3 | 6 | | 2018 | 3 | 2 | 5 | | 2019 | 4 | 6 | 10 | | 2020 | 3 | 6 | 9 | | 2021 | 2 | 1 | 3 | | 2022 | 0 | 4 | 4 |
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Below are the most recent publications written about "Anti-Inflammatory Agents, Non-Steroidal" by people in Profiles.
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Perea-Gil I, Seeger T, Bruyneel AAN, Termglinchan V, Monte E, Lim EW, Vadgama N, Furihata T, Gavidia AA, Arthur Ataam J, Bharucha N, Martinez-Amador N, Ameen M, Nair P, Serrano R, Kaur B, Feyen DAM, Diecke S, Snyder MP, Metallo CM, Mercola M, Karakikes I. Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy. Eur Heart J. 2022 09 21; 43(36):3477-3489.
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Kurlander JE, Barnes GD, Fisher A, Gonzalez JJ, Helminski D, Saini SD, Sengupta N, Yang YX, Scheiman J, Laine L. Association of Antisecretory Drugs with Upper Gastrointestinal Bleeding in Patients Using Oral Anticoagulants: A Systematic Review and Meta-Analysis. Am J Med. 2022 10; 135(10):1231-1243.e8.
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Parisien M, Lima LV, Dagostino C, El-Hachem N, Drury GL, Grant AV, Huising J, Verma V, Meloto CB, Silva JR, Dutra GGS, Markova T, Dang H, Tessier PA, Slade GD, Nackley AG, Ghasemlou N, Mogil JS, Allegri M, Diatchenko L. Acute inflammatory response via neutrophil activation protects against the development of chronic pain. Sci Transl Med. 2022 05 11; 14(644):eabj9954.
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Schrepf A, Hellman KM, Bohnert AM, Williams DA, Tu FF. Generalized sensory sensitivity is associated with comorbid pain symptoms: a replication study in women with dysmenorrhea. Pain. 2023 01 01; 164(1):142-148.
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Momesso GAC, Grossi-Oliveira GA, Silva WPP, Akira R, Chiba F, Polo TOB, de Lima Neto TJ, Rios BR, Bassi APF, Sumida DH, Han M, Miloro M, Faverani LP. A triple-blind randomized clinical trial of different associations between dexamethasone and non-steroids anti-inflammatories for preemptive action in third molar extractions. Sci Rep. 2021 12 27; 11(1):24445.
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Hamdeh S, Micic D, Hanauer S. Review article: drug-induced small bowel injury. Aliment Pharmacol Ther. 2021 12; 54(11-12):1370-1388.
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Shaffer SR, Huang E, Patel S, Rubin DT. Cost-Effectiveness of 5-Aminosalicylate Therapy in Combination With Biologics or Tofacitinib in the Treatment of Ulcerative Colitis. Am J Gastroenterol. 2021 01 01; 116(1):125-133.
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Pergola PE, Devalaraja M, Fishbane S, Chonchol M, Mathur VS, Smith MT, Lo L, Herzog K, Kakkar R, Davidson MH. Ziltivekimab for Treatment of Anemia of Inflammation in Patients on Hemodialysis: Results from a Phase 1/2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. J Am Soc Nephrol. 2021 01; 32(1):211-222.
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Oladosu FA, Tu FF, Garrison EF, Dillane KE, Roth GE, Hellman KM. Low Serum Naproxen Concentrations Are Associated with Minimal Pain Relief: A Preliminary Study in Women with Dysmenorrhea. Pain Med. 2020 11 01; 21(11):3102-3108.
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Moledina DG, Belliveau O, Yamamoto Y, Arora T, Carey KA, Churpek M, Martin M, Partridge CM, Mansour SG, Parikh CR, Koyner JL, Wilson FP. Variation in Best Practice Measures in Patients With Severe Hospital-Acquired Acute Kidney Injury: A Multicenter Study. Am J Kidney Dis. 2021 04; 77(4):547-549.
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