"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Descriptor ID |
D003424
|
| MeSH Number(s) |
C06.405.205.731.500 C06.405.469.432.500
|
| Concept/Terms |
Crohn Disease- Crohn Disease
- Crohn's Enteritis
- Regional Enteritis
- Crohn's Disease
- Crohns Disease
- Inflammatory Bowel Disease 1
Ileitis, Terminal- Ileitis, Terminal
- Terminal Ileitis
- Ileitis, Regional
- Regional Ileitides
- Regional Ileitis
|
Below are MeSH descriptors whose meaning is more general than "Crohn Disease".
Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".
This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 |
| 1996 | 4 | 1 | 5 |
| 1997 | 4 | 0 | 4 |
| 1998 | 6 | 1 | 7 |
| 1999 | 8 | 2 | 10 |
| 2000 | 15 | 1 | 16 |
| 2001 | 13 | 1 | 14 |
| 2002 | 17 | 2 | 19 |
| 2003 | 12 | 2 | 14 |
| 2004 | 23 | 0 | 23 |
| 2005 | 18 | 0 | 18 |
| 2006 | 13 | 4 | 17 |
| 2007 | 23 | 4 | 27 |
| 2008 | 11 | 3 | 14 |
| 2009 | 11 | 2 | 13 |
| 2010 | 12 | 1 | 13 |
| 2011 | 15 | 4 | 19 |
| 2012 | 14 | 3 | 17 |
| 2013 | 22 | 3 | 25 |
| 2014 | 16 | 0 | 16 |
| 2015 | 8 | 4 | 12 |
| 2016 | 20 | 3 | 23 |
| 2017 | 15 | 3 | 18 |
| 2018 | 22 | 1 | 23 |
| 2019 | 13 | 4 | 17 |
| 2020 | 22 | 3 | 25 |
| 2021 | 23 | 1 | 24 |
| 2022 | 29 | 0 | 29 |
| 2023 | 29 | 0 | 29 |
| 2024 | 15 | 7 | 22 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Crohn Disease" by people in Profiles.
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Mirikizumab Sustained Impact on Fatigue in Patients with Moderately to Severely Active Crohn's Disease in the Phase 2 AMAG Study. Inflamm Bowel Dis. 2025 02 06; 31(2):432-441.
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Efficacy and safety of filgotinib as induction and maintenance therapy for Crohn's disease (DIVERSITY): a phase 3, double-blind, randomised, placebo-controlled trial. Lancet Gastroenterol Hepatol. 2025 Feb; 10(2):138-153.
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Efficacy and Safety of GLP-1 Agonists on Metabolic Parameters in Non-diabetic Patients with Inflammatory Bowel Disease. Dig Dis Sci. 2024 Dec; 69(12):4437-4445.
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The Disease Severity Index for Inflammatory Bowel Disease Is a Valid Instrument that Predicts Complicated Disease. Inflamm Bowel Dis. 2024 11 04; 30(11):2064-2075.
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Single-center Experience With Upadacitinib for Adolescents With Refractory Inflammatory Bowel Disease. Inflamm Bowel Dis. 2024 11 04; 30(11):2057-2063.
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Dose escalation of biologics in biologic-naive patients with Crohn's disease: Outcomes from the ODESSA-CD study. J Manag Care Spec Pharm. 2024 Nov; 30(11):1276-1287.
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Noninvasive, microbiome-based diagnosis of inflammatory bowel disease. Nat Med. 2024 Dec; 30(12):3555-3567.
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Real-World Persistence of Successive Biologics in Patients With Inflammatory Bowel Disease: Findings From ROTARY. Inflamm Bowel Dis. 2024 10 03; 30(10):1776-1787.
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Evaluation of adverse clinical outcomes in patients with inflammatory bowel disease receiving different sequences of first- and second-line biologic treatments: findings from ROTARY. BMC Gastroenterol. 2024 Sep 17; 24(1):314.
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Early Intestinal Ultrasound Response to Biologic Therapy Predicts Endoscopic Remission in Children with Ileal Crohn's Disease: Results from the Prospective Super Sonic Study. J Crohns Colitis. 2024 Aug 06; 18(7):1002-1011.