"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Descriptor ID |
D003424
|
| MeSH Number(s) |
C06.405.205.731.500 C06.405.469.432.500
|
| Concept/Terms |
Crohn Disease- Crohn Disease
- Crohn's Enteritis
- Regional Enteritis
- Crohn's Disease
- Crohns Disease
- Inflammatory Bowel Disease 1
Ileitis, Terminal- Ileitis, Terminal
- Terminal Ileitis
- Ileitis, Regional
- Regional Ileitides
- Regional Ileitis
|
Below are MeSH descriptors whose meaning is more general than "Crohn Disease".
Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".
This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 |
| 1996 | 4 | 1 | 5 |
| 1997 | 4 | 0 | 4 |
| 1998 | 6 | 1 | 7 |
| 1999 | 8 | 2 | 10 |
| 2000 | 15 | 1 | 16 |
| 2001 | 13 | 1 | 14 |
| 2002 | 17 | 2 | 19 |
| 2003 | 12 | 2 | 14 |
| 2004 | 23 | 0 | 23 |
| 2005 | 18 | 0 | 18 |
| 2006 | 13 | 4 | 17 |
| 2007 | 23 | 4 | 27 |
| 2008 | 12 | 3 | 15 |
| 2009 | 11 | 2 | 13 |
| 2010 | 12 | 1 | 13 |
| 2011 | 15 | 4 | 19 |
| 2012 | 14 | 3 | 17 |
| 2013 | 22 | 3 | 25 |
| 2014 | 16 | 0 | 16 |
| 2015 | 8 | 4 | 12 |
| 2016 | 20 | 3 | 23 |
| 2017 | 15 | 3 | 18 |
| 2018 | 22 | 1 | 23 |
| 2019 | 13 | 4 | 17 |
| 2020 | 22 | 3 | 25 |
| 2021 | 23 | 1 | 24 |
| 2022 | 29 | 0 | 29 |
| 2023 | 29 | 0 | 29 |
| 2024 | 16 | 7 | 23 |
| 2025 | 6 | 0 | 6 |
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Below are the most recent publications written about "Crohn Disease" by people in Profiles.
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Subcutaneous infliximab (CT-P13 SC) as maintenance therapy for Crohn's disease and ulcerative colitis: 2-year results from open-label extensions of two randomized controlled trials (LIBERTY). J Crohns Colitis. 2025 Jun 04; 19(6).
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Deucravacitinib in patients with inflammatory bowel disease: 12-week efficacy and safety results from 3 randomized phase 2 studies in Crohn's disease and ulcerative colitis. J Crohns Colitis. 2025 Jun 04; 19(6).
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Genetic Mutations and Small Bowel Ulcerating Disease: Role in Diagnosis? Curr Gastroenterol Rep. 2025 May 21; 27(1):33.
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Association of bile acid diarrhea with symptoms and disease activity in Crohn's disease: post-hoc clinical trial analysis of serum 7a-hydroxy-4cholestern-3-one, C4, in patients with active Crohn's disease. J Crohns Colitis. 2025 May 08; 19(5).
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Mirikizumab Sustained Impact on Fatigue in Patients with Moderately to Severely Active Crohn's Disease in the Phase 2 AMAG Study. Inflamm Bowel Dis. 2025 Feb 06; 31(2):432-441.
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Genetic polymorphisms impacting clinical pharmacology of drugs used to treat inflammatory bowel disease: a precursor to multi-omics approach to precision medicine. Expert Rev Clin Immunol. 2025 Apr; 21(4):461-472.
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Efficacy and safety of filgotinib as induction and maintenance therapy for Crohn's disease (DIVERSITY): a phase 3, double-blind, randomised, placebo-controlled trial. Lancet Gastroenterol Hepatol. 2025 02; 10(2):138-153.
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Efficacy and Safety of GLP-1 Agonists on Metabolic Parameters in Non-diabetic Patients with Inflammatory Bowel Disease. Dig Dis Sci. 2024 Dec; 69(12):4437-4445.
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The Disease Severity Index for Inflammatory Bowel Disease Is a Valid Instrument that Predicts Complicated Disease. Inflamm Bowel Dis. 2024 11 04; 30(11):2064-2075.
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Single-center Experience With Upadacitinib for Adolescents With Refractory Inflammatory Bowel Disease. Inflamm Bowel Dis. 2024 11 04; 30(11):2057-2063.