"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Descriptor ID |
D003424
|
| MeSH Number(s) |
C06.405.205.731.500 C06.405.469.432.500
|
| Concept/Terms |
Crohn Disease- Crohn Disease
- Crohn's Enteritis
- Regional Enteritis
- Crohn's Disease
- Crohns Disease
- Inflammatory Bowel Disease 1
Ileitis, Terminal- Ileitis, Terminal
- Terminal Ileitis
- Ileitis, Regional
- Regional Ileitides
- Regional Ileitis
|
Below are MeSH descriptors whose meaning is more general than "Crohn Disease".
Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".
This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 1 | 5 |
| 1997 | 4 | 0 | 4 |
| 1998 | 6 | 1 | 7 |
| 1999 | 8 | 2 | 10 |
| 2000 | 15 | 1 | 16 |
| 2001 | 13 | 1 | 14 |
| 2002 | 17 | 2 | 19 |
| 2003 | 12 | 2 | 14 |
| 2004 | 23 | 0 | 23 |
| 2005 | 18 | 0 | 18 |
| 2006 | 13 | 4 | 17 |
| 2007 | 23 | 4 | 27 |
| 2008 | 12 | 3 | 15 |
| 2009 | 11 | 2 | 13 |
| 2010 | 12 | 2 | 14 |
| 2011 | 15 | 5 | 20 |
| 2012 | 14 | 3 | 17 |
| 2013 | 22 | 3 | 25 |
| 2014 | 16 | 0 | 16 |
| 2015 | 8 | 4 | 12 |
| 2016 | 20 | 3 | 23 |
| 2017 | 15 | 3 | 18 |
| 2018 | 22 | 1 | 23 |
| 2019 | 13 | 4 | 17 |
| 2020 | 22 | 3 | 25 |
| 2021 | 23 | 1 | 24 |
| 2022 | 30 | 0 | 30 |
| 2023 | 28 | 0 | 28 |
| 2024 | 17 | 7 | 24 |
| 2025 | 25 | 2 | 27 |
| 2026 | 19 | 0 | 19 |
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Below are the most recent publications written about "Crohn Disease" by people in Profiles.
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Five-year efficacy and safety of guselkumab for moderately to severely active Crohn's disease: Results from the phase 2 GALAXI 1 trial. Inflamm Bowel Dis. 2026 Sep 01; 32(9):1669-1682.
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Ultrasound criteria for transmural healing and response in Crohn's disease: a systematic review of definitions and thresholds. Inflamm Bowel Dis. 2026 Sep 01; 32(9):1707-1721.
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Corticosteroid-sparing effects of risankizumab versus ustekinumab in patients with moderately to severely active Crohn's disease: post hoc results from the phase 3b SEQUENCE trial. J Crohns Colitis. 2026 Jul 07; 20(7).
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Recovery of response and long-term outcomes following loss of response and dose escalation of subcutaneous infliximab: a post hoc analysis of the LIBERTY-CD & LIBERTY-UC trials. Inflamm Bowel Dis. 2026 Jul 01; 32(7):1235-1247.
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End-to-Side Ileocolonic Anastomosis After Ileocecectomy for Crohn's Disease Is a Safe Option With Low Recurrence. Dis Colon Rectum. 2026 Sep 01; 69(9):2283-2290.
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Combining Guselkumab with Upadacitinib Is Safe and Effective in the Treatment of Medically Complex Inflammatory Bowel Disease. Dig Dis Sci. 2026 Oct; 71(10):4831-4841.
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Intestinal ultrasound to detect postoperative recurrence in patients with Crohn's disease: an international, multidisciplinary, RAND/UCLA appropriateness method study. Lancet Gastroenterol Hepatol. 2026 Jul; 11(7):602-615.
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Spatial transcriptomics atlas of inflammatory bowel disease to guide implementation in research consortiums and clinical trials. Nat Commun. 2026 Apr 28; 17(1).
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Pre-Crohn's Disease Stool From Discordant Siblings Promotes the Development of Colitis in Germ-Free Mice. Gastroenterology. 2026 Sep; 171(3):489-503.
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Intestinal Ultrasound for Monitoring Postoperative Crohn's Disease: A Review and Visual Atlas. Inflamm Bowel Dis. 2026 Apr 01; 32(4):755-764.