"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Descriptor ID |
D003424
|
| MeSH Number(s) |
C06.405.205.731.500 C06.405.469.432.500
|
| Concept/Terms |
Crohn Disease- Crohn Disease
- Crohn's Enteritis
- Regional Enteritis
- Crohn's Disease
- Crohns Disease
- Inflammatory Bowel Disease 1
Ileitis, Terminal- Ileitis, Terminal
- Terminal Ileitis
- Ileitis, Regional
- Regional Ileitides
- Regional Ileitis
|
Below are MeSH descriptors whose meaning is more general than "Crohn Disease".
Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".
This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 1 | 5 |
| 1997 | 4 | 0 | 4 |
| 1998 | 6 | 1 | 7 |
| 1999 | 8 | 2 | 10 |
| 2000 | 15 | 1 | 16 |
| 2001 | 13 | 1 | 14 |
| 2002 | 17 | 2 | 19 |
| 2003 | 12 | 2 | 14 |
| 2004 | 23 | 0 | 23 |
| 2005 | 18 | 0 | 18 |
| 2006 | 13 | 4 | 17 |
| 2007 | 23 | 4 | 27 |
| 2008 | 12 | 3 | 15 |
| 2009 | 11 | 2 | 13 |
| 2010 | 12 | 2 | 14 |
| 2011 | 15 | 5 | 20 |
| 2012 | 14 | 3 | 17 |
| 2013 | 22 | 3 | 25 |
| 2014 | 16 | 0 | 16 |
| 2015 | 8 | 4 | 12 |
| 2016 | 20 | 3 | 23 |
| 2017 | 15 | 3 | 18 |
| 2018 | 22 | 1 | 23 |
| 2019 | 13 | 4 | 17 |
| 2020 | 22 | 3 | 25 |
| 2021 | 23 | 1 | 24 |
| 2022 | 29 | 0 | 29 |
| 2023 | 29 | 0 | 29 |
| 2024 | 17 | 7 | 24 |
| 2025 | 13 | 1 | 14 |
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Below are the most recent publications written about "Crohn Disease" by people in Profiles.
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Comparing Outcomes With Subcutaneous Infliximab (CT-P13 SC) by Baseline Immunosuppressant Use: A Post Hoc Analysis of the LIBERTY-CD and LIBERTY-UC Studies. Inflamm Bowel Dis. 2025 Oct 01; 31(10):2714-2724.
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Real-world Experience of Upadacitinib Reinduction and High-dose Maintenance Therapy in Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2026 Mar; 24(3):763-771.
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Sonographic Transmural Induction Outcomes Across Advanced Therapies in Crohn's Disease. Dig Dis Sci. 2025 Nov; 70(11):3912-3921.
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The position of anti-tumor necrosis factor agents for the treatment of adult patients with Crohn's disease. Expert Rev Gastroenterol Hepatol. 2025 Jul; 19(7):725-743.
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Histopathologic Evaluation and Single-cell Spatial Transcriptomics of the Colon Reveal Cellular and Molecular Abnormalities Linked to J-Pouch Failure in Patients With Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol. 2025; 19(10):101563.
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Subcutaneous infliximab (CT-P13 SC) as maintenance therapy for Crohn's disease and ulcerative colitis: 2-year results from open-label extensions of two randomized controlled trials (LIBERTY). J Crohns Colitis. 2025 Jun 04; 19(6).
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Deucravacitinib in patients with inflammatory bowel disease: 12-week efficacy and safety results from 3 randomized phase 2 studies in Crohn's disease and ulcerative colitis. J Crohns Colitis. 2025 Jun 04; 19(6).
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Genetic Mutations and Small Bowel Ulcerating Disease: Role in Diagnosis? Curr Gastroenterol Rep. 2025 May 21; 27(1):33.
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Association of bile acid diarrhea with symptoms and disease activity in Crohn's disease: post-hoc clinical trial analysis of serum 7a-hydroxy-4cholestern-3-one, C4, in patients with active Crohn's disease. J Crohns Colitis. 2025 May 08; 19(5).
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Defining normal bowel wall thickness in children with inflammatory bowel disease in deep remission: A multicenter study on behalf of the pediatric committee of the International Bowel Ultrasound Group (IBUS). J Pediatr Gastroenterol Nutr. 2025 Jul; 81(1):53-61.