"Arginase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ureahydrolase that catalyzes the hydrolysis of arginine or canavanine to yield L-ornithine (ORNITHINE) and urea. Deficiency of this enzyme causes HYPERARGININEMIA. EC 3.5.3.1.
| Descriptor ID |
D001119
|
| MeSH Number(s) |
D08.811.277.913.292
|
| Concept/Terms |
Arginase- Arginase
- Liver Immunoregulatory Protein
- Immunoregulatory Protein, Liver
- Protein, Liver Immunoregulatory
- Liver-Derived Inhibitory Protein
- Inhibitory Protein, Liver-Derived
- Liver Derived Inhibitory Protein
- Protein, Liver-Derived Inhibitory
- Hepatic Proliferation Inhibitor
- Inhibitor, Hepatic Proliferation
- Proliferation Inhibitor, Hepatic
|
Below are MeSH descriptors whose meaning is more general than "Arginase".
Below are MeSH descriptors whose meaning is more specific than "Arginase".
This graph shows the total number of publications written about "Arginase" by people in this website by year, and whether "Arginase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 2001 | 3 | 0 | 3 |
| 2006 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Arginase" by people in Profiles.
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Arginase Therapy Combines Effectively with Immune Checkpoint Blockade or Agonist Anti-OX40 Immunotherapy to Control Tumor Growth. Cancer Immunol Res. 2021 04; 9(4):415-429.
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Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism. J Biol Chem. 2016 09 09; 291(37):19517-31.
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Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis. J Clin Invest. 2015 Dec; 125(12):4699-713.
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All-trans retinoic acid induces arginase-1 and inducible nitric oxide synthase-producing dendritic cells with T cell inhibitory function. J Immunol. 2014 Jun 01; 192(11):5098-108.
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Mesenchymal stem cells improve medullary inflammation and fibrosis after revascularization of swine atherosclerotic renal artery stenosis. PLoS One. 2013; 8(7):e67474.
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Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation. J Sex Med. 2013 Jun; 10(6):1502-15.
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Arginase-1: a new immunohistochemical marker of hepatocytes and hepatocellular neoplasms. Am J Surg Pathol. 2010 Aug; 34(8):1147-54.
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Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19455-60.
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Arginine/arginase NO NO NO. Arterioscler Thromb Vasc Biol. 2006 Feb; 26(2):237-9.
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A useful ELISA system for human liver-type arginase, and its utility in diagnosis of liver diseases. Clin Biochem. 2001 Sep; 34(6):455-61.