"Antifibrinolytic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.
| Descriptor ID |
D000933
|
| MeSH Number(s) |
D27.505.519.421.500 D27.505.954.502.270.463.091
|
| Concept/Terms |
Plasmin Inhibitors- Plasmin Inhibitors
- Inhibitors, Plasmin
- Antiplasmins
- Plasmin Inhibitor
- Inhibitor, Plasmin
|
Below are MeSH descriptors whose meaning is more general than "Antifibrinolytic Agents".
Below are MeSH descriptors whose meaning is more specific than "Antifibrinolytic Agents".
This graph shows the total number of publications written about "Antifibrinolytic Agents" by people in this website by year, and whether "Antifibrinolytic Agents" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 4 | 1 | 5 |
| 2021 | 1 | 1 | 2 |
| 2022 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Antifibrinolytic Agents" by people in Profiles.
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Topical Hemostatic Agents in Burn Surgery: A Systematic Review. J Burn Care Res. 2023 03 02; 44(2):262-273.
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The effects of timing of prehospital tranexamic acid on outcomes after traumatic brain injury: Subanalysis of a randomized controlled trial. J Trauma Acute Care Surg. 2023 01 01; 94(1):86-92.
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Tranexamic acid is not inferior to placebo with respect to adverse events in suspected traumatic brain injury patients not in shock with a normal head computed tomography scan: A retrospective study of a randomized trial. J Trauma Acute Care Surg. 2022 07 01; 93(1):98-105.
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Life-Threatening Bleeding in Children: A Prospective Observational Study. Crit Care Med. 2021 11 01; 49(11):1943-1954.
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Viscoelastic Testing in Traumatic Brain Injury: Key Research Insights. Transfus Med Rev. 2021 10; 35(4):108-112.
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Tranexamic acid administration in the field does not affect admission thromboelastography after traumatic brain injury. J Trauma Acute Care Surg. 2020 11; 89(5):900-907.
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Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury. JAMA. 2020 09 08; 324(10):961-974.
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Early Tranexamic Acid Administration After Traumatic Brain Injury Is Associated With Reduced Syndecan-1 and Angiopoietin-2 in Patients With Traumatic Intracranial Hemorrhage. J Head Trauma Rehabil. 2020 Sep/Oct; 35(5):317-323.
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Tranexamic acid use for postpartum hemorrhage: A survey of Illinois birthing hospitals. J Clin Anesth. 2020 Dec; 67:109970.
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Blood-based biomarkers for prediction of intracranial hemorrhage and outcome in patients with moderate or severe traumatic brain injury. J Trauma Acute Care Surg. 2020 07; 89(1):80-86.