"Antifibrinolytic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.
| Descriptor ID |
D000933
|
| MeSH Number(s) |
D27.505.519.421.500 D27.505.954.502.270.463.091
|
| Concept/Terms |
Plasmin Inhibitors- Plasmin Inhibitors
- Inhibitors, Plasmin
- Antiplasmins
- Plasmin Inhibitor
- Inhibitor, Plasmin
|
Below are MeSH descriptors whose meaning is more general than "Antifibrinolytic Agents".
Below are MeSH descriptors whose meaning is more specific than "Antifibrinolytic Agents".
This graph shows the total number of publications written about "Antifibrinolytic Agents" by people in this website by year, and whether "Antifibrinolytic Agents" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 4 | 1 | 5 |
| 2021 | 1 | 1 | 2 |
| 2022 | 2 | 0 | 2 |
| 2023 | 5 | 0 | 5 |
| 2024 | 4 | 2 | 6 |
| 2025 | 4 | 0 | 4 |
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Below are the most recent publications written about "Antifibrinolytic Agents" by people in Profiles.
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Prehospital Tranexamic Acid and First 24-Hour Blood Product Transfusion in Patients with Isolated Traumatic Brain Injury. J Am Coll Surg. 2025 Jul 01; 241(1):7-15.
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Association between coagulation biomarkers, intracranial hemorrhage types, and tranexamic acid treatments in early traumatic brain injury. J Trauma Acute Care Surg. 2025 Sep 01; 99(3):468-476.
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Age matters: A Secondary Analysis of Endothelial Biomarkers in the Prehospital Tranexamic Acid for Traumatic Brain Injury Trial. J Trauma Acute Care Surg. 2025 Oct 01; 99(4):541-550.
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Association between prehospital tranexamic acid and cerebral edema in patients with moderate or severe traumatic brain injury. J Trauma Acute Care Surg. 2025 May 01; 98(5):794-797.
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Intravenous Versus Intraosseous Use of Tranexamic Acid in Patients With Traumatic Brain Injury. J Surg Res. 2024 Oct; 302:798-804.
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Evaluating and Updating the IMPACT Model to Predict Outcomes in Two Contemporary North American Traumatic Brain Injury Cohorts. J Neurotrauma. 2025 Sep; 42(17-18):1585-1600.
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The Association Between Tranexamic Acid and Seizures in Moderate or Severe Traumatic Brain Injury. J Surg Res. 2024 Sep; 301:359-364.
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Predicting Progression of Intracranial Hemorrhage in the Prehospital TXA for TBI Trial. J Neurotrauma. 2024 10; 41(19-20):2349-2361.
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The effects of prehospital TXA on mortality and neurologic outcomes in patients with traumatic intracranial hemorrhage: A subgroup analysis from the prehospital TXA for TBI trial. J Trauma Acute Care Surg. 2024 Oct 01; 97(4):572-580.
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Prehospital tranexamic acid is associated with a survival benefit without an increase in complications: Results of two harmonized randomized clinical trials. J Trauma Acute Care Surg. 2024 Nov 01; 97(5):697-702.