"Chloroquine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
| Descriptor ID |
D002738
|
| MeSH Number(s) |
D03.633.100.810.050.180
|
| Concept/Terms |
Chloroquine Sulfate- Chloroquine Sulfate
- Sulfate, Chloroquine
- Chloroquine Sulphate
- Sulphate, Chloroquine
|
Below are MeSH descriptors whose meaning is more general than "Chloroquine".
Below are MeSH descriptors whose meaning is more specific than "Chloroquine".
This graph shows the total number of publications written about "Chloroquine" by people in this website by year, and whether "Chloroquine" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chloroquine" by people in Profiles.
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Chloroquine- and Hydroxychloroquine-Induced Cardiomyopathy: A Case Report and Brief Literature Review. Am J Clin Pathol. 2021 05 18; 155(6):793-801.
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Structure and drug resistance of the Plasmodium falciparum transporter PfCRT. Nature. 2019 12; 576(7786):315-320.
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NF-?B Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance. J Biol Chem. 2017 02 24; 292(8):3379-3388.
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Anti-malarial chemoprophylaxis following evacuation from Afghanistan. J R Army Med Corps. 2012 Mar; 158(1):38-40; discussion 40.
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Akt and autophagy cooperate to promote survival of drug-resistant glioma. Sci Signal. 2010 Nov 09; 3(147):ra81.
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Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine. J Biol Chem. 2009 Sep 25; 284(39):26816-30.
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Plasmodium falciparum gametocytaemia with chloroquine chemotherapy in persistent malaria in an endemic area of India. Indian J Med Res. 2009 Mar; 129(3):299-304.
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Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes. Cardiovasc Res. 1998 Jun; 38(3):711-8.
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A trial of Fansidar plus chloroquine or Fansidar alone for the treatment of uncomplicated malaria in Gambian children. Trans R Soc Trop Med Hyg. 1998 Jan-Feb; 92(1):73-6.
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Contractile activity modulates actin synthesis and turnover in cultured neonatal rat heart cells. Circ Res. 1993 Jul; 73(1):172-83.