"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
| Descriptor ID |
D001343
|
| MeSH Number(s) |
G04.146.399 G04.417.350.091
|
| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Macro-autophagy
- Macro autophagy
- Macro-autophagies
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
- Macroautophagy
- Macroautophagies
- Autophagocytosis
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
- Autophagic Programmed Cell Death
|
Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 7 | 0 | 7 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 6 | 1 | 7 |
| 2011 | 3 | 1 | 4 |
| 2012 | 6 | 1 | 7 |
| 2013 | 6 | 1 | 7 |
| 2014 | 3 | 7 | 10 |
| 2015 | 9 | 4 | 13 |
| 2016 | 6 | 1 | 7 |
| 2017 | 7 | 7 | 14 |
| 2018 | 4 | 2 | 6 |
| 2019 | 5 | 1 | 6 |
| 2020 | 7 | 2 | 9 |
| 2021 | 6 | 5 | 11 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 2 | 2 |
| 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Autophagy" by people in Profiles.
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Gene-based burden tests of rare germline variants identify six cancer susceptibility genes. Nat Genet. 2024 Nov; 56(11):2422-2433.
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Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's disease. Life Sci Alliance. 2024 Nov; 7(11).
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Reduction of spermine synthase enhances autophagy to suppress Tau accumulation. Cell Death Dis. 2024 May 13; 15(5):333.
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Copper enhances aggregational toxicity of mutant huntingtin in a Drosophila model of Huntington's Disease. Biochim Biophys Acta Mol Basis Dis. 2024 Jan; 1870(1):166928.
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Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland. JCI Insight. 2023 06 22; 8(12).
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Genome of Paspalum vaginatum and the role of trehalose mediated autophagy in increasing maize biomass. Nat Commun. 2022 12 13; 13(1):7731.
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Inside the ß Cell: Molecular Stress Response Pathways in Diabetes Pathogenesis. Endocrinology. 2022 11 14; 164(1).
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Docosahexaenoic Acid Suppresses Oxidative Stress-Induced Autophagy and Cell Death via the AMPK-Dependent Signaling Pathway in Immortalized Fischer Rat Schwann Cells 1. Int J Mol Sci. 2022 Apr 15; 23(8).
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In search of autophagy biomarkers in breast cancer: Receptor status and drug agnostic transcriptional changes during autophagy flux in cell lines. PLoS One. 2022; 17(1):e0262134.
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Early DNA damage detection and cellular autophagy as drivers of stress-adaptive H2S production: A paradox resolved. Cell Chem Biol. 2021 12 16; 28(12):1665-1668.