"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
| Descriptor ID |
D001343
|
| MeSH Number(s) |
G04.146.399 G04.417.350.091
|
| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Macro-autophagy
- Macro autophagy
- Macro-autophagies
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
- Macroautophagy
- Macroautophagies
- Autophagocytosis
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
- Autophagic Programmed Cell Death
|
Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 7 | 0 | 7 |
| 2008 | 2 | 1 | 3 |
| 2009 | 2 | 2 | 4 |
| 2010 | 7 | 1 | 8 |
| 2011 | 3 | 2 | 5 |
| 2012 | 7 | 1 | 8 |
| 2013 | 6 | 1 | 7 |
| 2014 | 3 | 7 | 10 |
| 2015 | 9 | 4 | 13 |
| 2016 | 6 | 3 | 9 |
| 2017 | 7 | 8 | 15 |
| 2018 | 4 | 2 | 6 |
| 2019 | 6 | 1 | 7 |
| 2020 | 7 | 1 | 8 |
| 2021 | 6 | 5 | 11 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 2 | 2 |
| 2024 | 3 | 1 | 4 |
| 2025 | 1 | 5 | 6 |
To return to the timeline,
click here.
Below are the most recent publications written about "Autophagy" by people in Profiles.
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Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy. Nat Metab. 2025 Dec; 7(12):2589-2611.
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Regulatory Roles of IGF2R in Insulin Secretion and Adaptive ß-Cell Proliferation. Diabetes. 2025 Dec 01; 74(12):2351-2364.
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YTHDF2 regulates self non-coding RNA metabolism to control inflammation and tumorigenesis. Nat Commun. 2025 Nov 12; 16(1):9946.
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ABCC6 Transporter Contributed to Cisplatin Resistance on Bladder Cancer. Int J Med Sci. 2025; 22(15):3895-3905.
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DGAT1 Inhibition Enhances Olaparib-Induced Lipotoxic Apoptosis in Metastatic Castration-Resistant Prostate Cancer. FASEB J. 2025 Aug 15; 39(15):e70925.
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Bone marrow niches orchestrate stem-cell hierarchy and immune tolerance. Nature. 2025 02; 638(8049):206-215.
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Gene-based burden tests of rare germline variants identify six cancer susceptibility genes. Nat Genet. 2024 Nov; 56(11):2422-2433.
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Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's disease. Life Sci Alliance. 2024 11; 7(11).
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VAMP2 controls murine epidermal differentiation and carcinogenesis by regulation of nucleophagy. Dev Cell. 2024 08 05; 59(15):2005-2016.e4.
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Reduction of spermine synthase enhances autophagy to suppress Tau accumulation. Cell Death Dis. 2024 05 13; 15(5):333.