 Central Nervous System Depressants
"Central Nervous System Depressants" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).
| Descriptor ID |
D002492
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| MeSH Number(s) |
D27.505.696.277 D27.505.954.427.210
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Central Nervous System Depressants".
Below are MeSH descriptors whose meaning is more specific than "Central Nervous System Depressants".
This graph shows the total number of publications written about "Central Nervous System Depressants" by people in this website by year, and whether "Central Nervous System Depressants" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 | | 1998 | 1 | 1 | 2 | | 2000 | 4 | 1 | 5 | | 2001 | 3 | 0 | 3 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 0 | 2 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 1 | 3 | | 2010 | 1 | 1 | 2 | | 2011 | 1 | 1 | 2 | | 2012 | 2 | 2 | 4 | | 2013 | 3 | 1 | 4 | | 2014 | 2 | 0 | 2 | | 2015 | 3 | 1 | 4 | | 2016 | 2 | 1 | 3 | | 2017 | 2 | 0 | 2 |
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Below are the most recent publications written about "Central Nervous System Depressants" by people in Profiles.
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Gorka SM, Phan KL, Childs E. Acute calming effects of alcohol are associated with disruption of the salience network. Addict Biol. 2018 05; 23(3):921-930.
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Berman ME, Fanning JR, Guillot CR, Marsic A, Bullock J, Nadorff MR, McCloskey MS. Effect of alcohol dose on deliberate self-harm in men and women. J Consult Clin Psychol. 2017 Sep; 85(9):854-861.
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Barbier E, Johnstone AL, Khomtchouk BB, Tapocik JD, Pitcairn C, Rehman F, Augier E, Borich A, Schank JR, Rienas CA, Van Booven DJ, Sun H, Nätt D, Wahlestedt C, Heilig M. Dependence-induced increase of alcohol self-administration and compulsive drinking mediated by the histone methyltransferase PRDM2. Mol Psychiatry. 2017 Dec; 22(12):1746-1758.
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Abburi C, Wolfman SL, Metz RA, Kamber R, McGehee DS, McDaid J. Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum. eNeuro. 2016 Jul-Aug; 3(4).
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McDaid J, Abburi C, Wolfman SL, Gallagher K, McGehee DS. Ethanol-Induced Motor Impairment Mediated by Inhibition of a7 Nicotinic Receptors. J Neurosci. 2016 07 20; 36(29):7768-78.
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Patton MH, Roberts BM, Lovinger DM, Mathur BN. Ethanol Disinhibits Dorsolateral Striatal Medium Spiny Neurons Through Activation of A Presynaptic Delta Opioid Receptor. Neuropsychopharmacology. 2016 06; 41(7):1831-40.
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Talani G, Lovinger DM. Interactions between ethanol and the endocannabinoid system at GABAergic synapses on basolateral amygdala principal neurons. Alcohol. 2015 Dec; 49(8):781-94.
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Siciliano CA, Calipari ES, Cuzon Carlson VC, Helms CM, Lovinger DM, Grant KA, Jones SR. Voluntary ethanol intake predicts ?-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques. J Neurosci. 2015 Apr 15; 35(15):5959-68.
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N'Gouemo P, Akinfiresoye LR, Allard JS, Lovinger DM. Alcohol Withdrawal-Induced Seizure Susceptibility is Associated with an Upregulation of CaV1.3 Channels in the Rat Inferior Colliculus. Int J Neuropsychopharmacol. 2015 Jan 02; 18(7):pyu123.
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Hausknecht K, Haj-Dahmane S, Shen YL, Vezina P, Dlugos C, Shen RY. Excitatory synaptic function and plasticity is persistently altered in ventral tegmental area dopamine neurons after prenatal ethanol exposure. Neuropsychopharmacology. 2015 Mar; 40(4):893-905.
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